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Immune cell profiling reveals expanded stem cell-like memory T cells in anti-GAD65-associated neurological syndromes.

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Title: Immune cell profiling reveals expanded stem cell-like memory T cells in anti-GAD65-associated neurological syndromes.
Authors: Barman S; Department of Neurology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf 40225, Germany., Räuber S; Department of Neurology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf 40225, Germany., Eisenhut K; Institute of Clinical Neuroimmunology, University Hospital, Ludwig-Maximilians-Universität München, Munich 81377, Germany.; Biomedical Center, Faculty of Medicine, Ludwig-Maximilians-Universität München, Martinsried 82152, Germany., Esser D; Institute of Clinical Chemistry, University Hospital Schleswig-Holstein, Kiel 24105/Lübeck 23538, Germany., van Duijn M; Department of Neurology, Erasmus MC University Medical Center, Rotterdam 3015 GD, the Netherlands., Scharf M; Institute for Experimental Immunology, affiliated to Euroimmun Medizinische Labordiagnostika Aktiengesellschaft, Lübeck 23560, Germany., Herrera-Rivero M; Institute of Epidemiology and Social Medicine, University of Münster, Münster 48149, Germany., Disse P; Department of Neurology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf 40225, Germany., Preuth LM; Department of Neurology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf 40225, Germany., Gulyaeva V; Department of Neurology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf 40225, Germany., Schwan I; Department of Neurology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf 40225, Germany., Vom Stein E; Department of Neurology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf 40225, Germany., Jonas M; Department of Neurology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf 40225, Germany., Pul D; Department of Neurology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf 40225, Germany., Heming M; Department of Neurology, University Hospital Münster, Münster 48149, Germany., Müller-Miny L; Department of Neurology, University Hospital Münster, Münster 48149, Germany., Paunovic M; Department of Neurology, Erasmus MC University Medical Center, Rotterdam 3015 GD, the Netherlands., Strippel C; Department of Neurology, University Hospital Münster, Münster 48149, Germany., Haholu E; Institute of Clinical Neuroimmunology, University Hospital, Ludwig-Maximilians-Universität München, Munich 81377, Germany.; Biomedical Center, Faculty of Medicine, Ludwig-Maximilians-Universität München, Martinsried 82152, Germany.; Graduate School of Systemic Neurosciences, Ludwig-Maximilians-Universität München, Planegg 82152, Germany., Bartosch J; Institute of Clinical Neuroimmunology, University Hospital, Ludwig-Maximilians-Universität München, Munich 81377, Germany.; Biomedical Center, Faculty of Medicine, Ludwig-Maximilians-Universität München, Martinsried 82152, Germany.; Graduate School of Systemic Neurosciences, Ludwig-Maximilians-Universität München, Planegg 82152, Germany., Kaufmann E; Department of Neurology, University Hospital, Ludwig-Maximilians-Universität München, Munich 81377, Germany., Dargvainiene J; Institute of Clinical Chemistry, University Hospital Schleswig-Holstein, Kiel 24105/Lübeck 23538, Germany., Kahl S; Department of Endocrinology and Diabetology, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University, Düsseldorf 40225, Germany.; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Institute for Diabetes Research at Heinrich-Heine-University, Düsseldorf 40225, Germany.; German Center for Diabetes Research, München-Neuherberg 85764, Germany., Ringelstein M; Department of Neurology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf 40225, Germany.; Department of Neurology, Center for Neurology and Neuropsychiatry, Landschaftsverband Rheinland-Klinikum, Heinrich Heine University, Düsseldorf 40629, Germany., Bindels E; Department of Hematology, Erasmus MC University Medical Center, Rotterdam 3015 GD, the Netherlands., Wiendl H; Department of Neurology, University Hospital Münster, Münster 48149, Germany., Stoecklein NH; Department of General, Visceral and Pediatric Surgery, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf 40225, Germany., Fischer J; Institute for Transplantation Diagnostics and Cell Therapeutics, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf 40225, Germany., Goebels N; Department of Neurology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf 40225, Germany., Komorowski L; Institute for Experimental Immunology, affiliated to Euroimmun Medizinische Labordiagnostika Aktiengesellschaft, Lübeck 23560, Germany., Roden M; Department of Endocrinology and Diabetology, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University, Düsseldorf 40225, Germany.; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Institute for Diabetes Research at Heinrich-Heine-University, Düsseldorf 40225, Germany.; German Center for Diabetes Research, München-Neuherberg 85764, Germany., Rossi A; Genome Engineering and Model Development Lab, Institut für umweltmedizinische Forschung-Leibniz Research Institute for Environmental Medicine, Düsseldorf 40225, Germany., Stoll M; Department of Genetic Epidemiology, Institute of Human Genetics, University of Münster, Münster 48149, Germany., Becker AJ; Institute of Cellular Neurosciences II, University Hospital Bonn, Bonn 53127, Germany., Hamed M; Clinic for Neurosurgery, University Hospital of Bonn, Bonn 53127, Germany., Bien CG; Department of Epileptology, Bethel Epilepsy Center, Medical School Ostwestfalen-Lippe, Bielefeld University, Bielefeld 33617, Germany., Höftberger R; Division of Neuropathology and Neurochemistry, Department of Neurology and Comprehensive Center for Clinical Neurosciences and Mental Health, Medical University of Vienna, Vienna 1090, Austria., Bauer J; Department of Neuroimmunology, Centre for Brain Research, Medical University of Vienna, Vienna 1090, Austria., Meuth SG; Department of Neurology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf 40225, Germany., Titulaer MJ; Department of Neurology, Erasmus MC University Medical Center, Rotterdam 3015 GD, the Netherlands., Leypoldt F; Institute of Clinical Chemistry, University Hospital Schleswig-Holstein, Kiel 24105/Lübeck 23538, Germany.; Department of Neurology, University Hospital Schleswig-Holstein, Kiel 24105, Germany., Meyer zu Hörste G; Department of Neurology, University Hospital Münster, Münster 48149, Germany., Thaler F; Institute of Clinical Neuroimmunology, University Hospital, Ludwig-Maximilians-Universität München, Munich 81377, Germany.; Biomedical Center, Faculty of Medicine, Ludwig-Maximilians-Universität München, Martinsried 82152, Germany., Melzer N; Department of Neurology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf 40225, Germany.
Corporate Authors: in cooperation with the Erasmus Medical Center-AIE Study Group, German Network for Research on Autoimmune Encephalitis
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 Mar 31; Vol. 123 (13), pp. e2514753123. Date of Electronic Publication: 2026 Mar 25.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
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  Data: Immune cell profiling reveals expanded stem cell-like memory T cells in anti-GAD65-associated neurological syndromes.
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              Value: 1091-6490
          Numbering:
            – Type: volume
              Value: 123
            – Type: issue
              Value: 13
          Titles:
            – TitleFull: Proceedings of the National Academy of Sciences of the United States of America
              Type: main
ResultId 1