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N,N-dimethyltryptamine elicits antidepressant and anxiolytic effects in helpless mice: a comparative study with S-ketamine.

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Title: N,N-dimethyltryptamine elicits antidepressant and anxiolytic effects in helpless mice: a comparative study with S-ketamine.
Authors: de Sousa-Silva AN; Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho, s/n Campus Universitário, Lagoa Nova, Natal, RN, 59078-900, Brazil., Moura CA; Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho, s/n Campus Universitário, Lagoa Nova, Natal, RN, 59078-900, Brazil., de Oliveira Torres CI; Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho, s/n Campus Universitário, Lagoa Nova, Natal, RN, 59078-900, Brazil., Marques VB; Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho, s/n Campus Universitário, Lagoa Nova, Natal, RN, 59078-900, Brazil., do Nascimento Silva JM; Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho, s/n Campus Universitário, Lagoa Nova, Natal, RN, 59078-900, Brazil., Lobão-Soares B; Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho, s/n Campus Universitário, Lagoa Nova, Natal, RN, 59078-900, Brazil., Ruschi Silva S; Brain Institute, Federal University of Rio Grande do Norte, Natal, RN, Brazil., Galvão-Coelho NL; Department of Physiology and Behavior and Postgraduate Program in Psychobiology, Federal University of Rio Grande do Norte, Natal, Brazil., Palhano-Fontes F; Brain Institute, Federal University of Rio Grande do Norte, Natal, RN, Brazil., Araújo DB; Brain Institute, Federal University of Rio Grande do Norte, Natal, RN, Brazil., da Silva ED Jr; Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho, s/n Campus Universitário, Lagoa Nova, Natal, RN, 59078-900, Brazil., Gavioli EC; Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho, s/n Campus Universitário, Lagoa Nova, Natal, RN, 59078-900, Brazil. Electronic address: elaine.gavioli@ufrn.br.
Source: Neuropharmacology [Neuropharmacology] 2026 Jul 01; Vol. 292, pp. 110947. Date of Electronic Publication: 2026 Mar 23.
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: Pergamon Press Country of Publication: England NLM ID: 0236217 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7064 (Electronic) Linking ISSN: 00283908 NLM ISO Abbreviation: Neuropharmacology Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: N,N-dimethyltryptamine elicits antidepressant and anxiolytic effects in helpless mice: a comparative study with S-ketamine.
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  Data: <searchLink fieldCode="AU" term="%22de+Sousa-Silva+AN%22">de Sousa-Silva AN</searchLink>; Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho, s/n Campus Universitário, Lagoa Nova, Natal, RN, 59078-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Moura+CA%22">Moura CA</searchLink>; Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho, s/n Campus Universitário, Lagoa Nova, Natal, RN, 59078-900, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Oliveira+Torres+CI%22">de Oliveira Torres CI</searchLink>; Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho, s/n Campus Universitário, Lagoa Nova, Natal, RN, 59078-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Marques+VB%22">Marques VB</searchLink>; Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho, s/n Campus Universitário, Lagoa Nova, Natal, RN, 59078-900, Brazil.<br /><searchLink fieldCode="AU" term="%22do+Nascimento+Silva+JM%22">do Nascimento Silva JM</searchLink>; Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho, s/n Campus Universitário, Lagoa Nova, Natal, RN, 59078-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Lobão-Soares+B%22">Lobão-Soares B</searchLink>; Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho, s/n Campus Universitário, Lagoa Nova, Natal, RN, 59078-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Ruschi+Silva+S%22">Ruschi Silva S</searchLink>; Brain Institute, Federal University of Rio Grande do Norte, Natal, RN, Brazil.<br /><searchLink fieldCode="AU" term="%22Galvão-Coelho+NL%22">Galvão-Coelho NL</searchLink>; Department of Physiology and Behavior and Postgraduate Program in Psychobiology, Federal University of Rio Grande do Norte, Natal, Brazil.<br /><searchLink fieldCode="AU" term="%22Palhano-Fontes+F%22">Palhano-Fontes F</searchLink>; Brain Institute, Federal University of Rio Grande do Norte, Natal, RN, Brazil.<br /><searchLink fieldCode="AU" term="%22Araújo+DB%22">Araújo DB</searchLink>; Brain Institute, Federal University of Rio Grande do Norte, Natal, RN, Brazil.<br /><searchLink fieldCode="AU" term="%22da+Silva+ED+Jr%22">da Silva ED Jr</searchLink>; Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho, s/n Campus Universitário, Lagoa Nova, Natal, RN, 59078-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Gavioli+EC%22">Gavioli EC</searchLink>; Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, Av. Senador Salgado Filho, s/n Campus Universitário, Lagoa Nova, Natal, RN, 59078-900, Brazil. Electronic address: elaine.gavioli@ufrn.br.
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  Data: <searchLink fieldCode="JN" term="%220236217%22">Neuropharmacology</searchLink> [Neuropharmacology] 2026 Jul 01; Vol. 292, pp. 110947. <i>Date of Electronic Publication: </i>2026 Mar 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Pergamon+Press%22">Pergamon Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0236217 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-7064 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200283908%22">00283908 </searchLink><i>NLM ISO Abbreviation: </i>Neuropharmacology <i>Subsets: </i>MEDLINE
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              Text: 2026 Jul 01
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