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Transcriptome analysis of the prefrontal cortex identifies inflammatory genes associated with cognitive impairment in a model of multiple sclerosis.

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Title: Transcriptome analysis of the prefrontal cortex identifies inflammatory genes associated with cognitive impairment in a model of multiple sclerosis.
Authors: Zupo L; Section of Human Anatomy, Department of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy., Adinolfi A; Section of Human Anatomy, Department of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy., Pieraccioli M; Section of Human Anatomy, Department of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.; Gemelli Science and Technology Park (GSTeP)-Organoids Research Core Facility, Fondazione Policlinico Agostino Gemelli IRCCS, Rome, Italy., Guerra M; Section of Human Anatomy, Department of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy., Corvino V; Section of Human Anatomy, Department of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy., Ria F; Section of General Pathology, Department of Translational Medicine and Surgery, Università Cattolica del Sacro Cuore, Rome, Italy., Ceci V; Institute of Translational Pharmacology, National Research Council, Rome, Italy.; Laboratory of Resolution of Neuroinflammation, IRCCS Fondazione Santa Lucia, Rome, Italy., Chiurchiù V; Institute of Translational Pharmacology, National Research Council, Rome, Italy.; Laboratory of Resolution of Neuroinflammation, IRCCS Fondazione Santa Lucia, Rome, Italy., Gaetani L; Section of Neurology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy., Sperandei S; Section of Neurology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy., Di Filippo M; Section of Neurology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy., Di Sante G; Department of Medicine and Surgery, Section of Human, Clinical and Forensic Anatomy, University of Perugia, Perugia, Italy., Geloso MC; Section of Human Anatomy, Department of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy. mariaconcetta.geloso@unicatt.it.; Gemelli Science and Technology Park (GSTeP)-Organoids Research Core Facility, Fondazione Policlinico Agostino Gemelli IRCCS, Rome, Italy. mariaconcetta.geloso@unicatt.it., Sette C; Section of Human Anatomy, Department of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy. claudio.sette@unicatt.it.; Gemelli Science and Technology Park (GSTeP)-Organoids Research Core Facility, Fondazione Policlinico Agostino Gemelli IRCCS, Rome, Italy. claudio.sette@unicatt.it.
Source: Cell death discovery [Cell Death Discov] 2026 Mar 25; Vol. 12 (1). Date of Electronic Publication: 2026 Mar 25.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Transcriptome analysis of the prefrontal cortex identifies inflammatory genes associated with cognitive impairment in a model of multiple sclerosis.
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  Data: <searchLink fieldCode="AU" term="%22Zupo+L%22">Zupo L</searchLink>; Section of Human Anatomy, Department of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Adinolfi+A%22">Adinolfi A</searchLink>; Section of Human Anatomy, Department of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Pieraccioli+M%22">Pieraccioli M</searchLink>; Section of Human Anatomy, Department of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.; Gemelli Science and Technology Park (GSTeP)-Organoids Research Core Facility, Fondazione Policlinico Agostino Gemelli IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Guerra+M%22">Guerra M</searchLink>; Section of Human Anatomy, Department of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Corvino+V%22">Corvino V</searchLink>; Section of Human Anatomy, Department of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Ria+F%22">Ria F</searchLink>; Section of General Pathology, Department of Translational Medicine and Surgery, Università Cattolica del Sacro Cuore, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Ceci+V%22">Ceci V</searchLink>; Institute of Translational Pharmacology, National Research Council, Rome, Italy.; Laboratory of Resolution of Neuroinflammation, IRCCS Fondazione Santa Lucia, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Chiurchiù+V%22">Chiurchiù V</searchLink>; Institute of Translational Pharmacology, National Research Council, Rome, Italy.; Laboratory of Resolution of Neuroinflammation, IRCCS Fondazione Santa Lucia, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Gaetani+L%22">Gaetani L</searchLink>; Section of Neurology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22Sperandei+S%22">Sperandei S</searchLink>; Section of Neurology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Filippo+M%22">Di Filippo M</searchLink>; Section of Neurology, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Sante+G%22">Di Sante G</searchLink>; Department of Medicine and Surgery, Section of Human, Clinical and Forensic Anatomy, University of Perugia, Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22Geloso+MC%22">Geloso MC</searchLink>; Section of Human Anatomy, Department of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy. mariaconcetta.geloso@unicatt.it.; Gemelli Science and Technology Park (GSTeP)-Organoids Research Core Facility, Fondazione Policlinico Agostino Gemelli IRCCS, Rome, Italy. mariaconcetta.geloso@unicatt.it.<br /><searchLink fieldCode="AU" term="%22Sette+C%22">Sette C</searchLink>; Section of Human Anatomy, Department of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy. claudio.sette@unicatt.it.; Gemelli Science and Technology Park (GSTeP)-Organoids Research Core Facility, Fondazione Policlinico Agostino Gemelli IRCCS, Rome, Italy. claudio.sette@unicatt.it.
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  Data: <searchLink fieldCode="JN" term="%22101665035%22">Cell death discovery</searchLink> [Cell Death Discov] 2026 Mar 25; Vol. 12 (1). <i>Date of Electronic Publication: </i>2026 Mar 25.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101665035 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2058-7716 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220587716%22">20587716 </searchLink><i>NLM ISO Abbreviation: </i>Cell Death Discov <i>Subsets: </i>PubMed not MEDLINE
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