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Exposed phosphatidylserine is an inhibitory molecule in T cell exhaustion.

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Title: Exposed phosphatidylserine is an inhibitory molecule in T cell exhaustion.
Authors: Medina CB; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA., Sobierajska E; Department of Urology, Emory University School of Medicine, Atlanta, GA, USA.; Winship Cancer Institute of Emory University, Atlanta, GA, USA., Gong M; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA., McManus DT; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA., Thapa M; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA., Lee J; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA., Im SJ; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA., Toombs JE; Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, TX, USA., Mitchell JM; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA., Wang Y; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA., Carlisle JW; Winship Cancer Institute of Emory University, Atlanta, GA, USA., Freeman GJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Master VA; Department of Urology, Emory University School of Medicine, Atlanta, GA, USA.; Winship Cancer Institute of Emory University, Atlanta, GA, USA., Ramalingam SS; Winship Cancer Institute of Emory University, Atlanta, GA, USA., Kissick HT; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.; Department of Urology, Emory University School of Medicine, Atlanta, GA, USA.; Winship Cancer Institute of Emory University, Atlanta, GA, USA., Li S; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.; Department of Immunology, University of Connecticut, Farmington, CT, USA., Brekken RA; Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, TX, USA., Ahmed R; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA. rahmed@emory.edu.; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA. rahmed@emory.edu.
Source: Nature [Nature] 2026 May; Vol. 653 (8115), pp. 879-887. Date of Electronic Publication: 2026 Mar 25.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Medina+CB%22">Medina CB</searchLink>; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Sobierajska+E%22">Sobierajska E</searchLink>; Department of Urology, Emory University School of Medicine, Atlanta, GA, USA.; Winship Cancer Institute of Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Gong+M%22">Gong M</searchLink>; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.<br /><searchLink fieldCode="AU" term="%22McManus+DT%22">McManus DT</searchLink>; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Thapa+M%22">Thapa M</searchLink>; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Im+SJ%22">Im SJ</searchLink>; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Toombs+JE%22">Toombs JE</searchLink>; Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Mitchell+JM%22">Mitchell JM</searchLink>; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.<br /><searchLink fieldCode="AU" term="%22Carlisle+JW%22">Carlisle JW</searchLink>; Winship Cancer Institute of Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Freeman+GJ%22">Freeman GJ</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Master+VA%22">Master VA</searchLink>; Department of Urology, Emory University School of Medicine, Atlanta, GA, USA.; Winship Cancer Institute of Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Ramalingam+SS%22">Ramalingam SS</searchLink>; Winship Cancer Institute of Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Kissick+HT%22">Kissick HT</searchLink>; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA.; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.; Department of Urology, Emory University School of Medicine, Atlanta, GA, USA.; Winship Cancer Institute of Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.; Department of Immunology, University of Connecticut, Farmington, CT, USA.<br /><searchLink fieldCode="AU" term="%22Brekken+RA%22">Brekken RA</searchLink>; Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Ahmed+R%22">Ahmed R</searchLink>; Emory Vaccine Center, Emory University School of Medicine, Atlanta, GA, USA. rahmed@emory.edu.; Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA. rahmed@emory.edu.
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  Data: <searchLink fieldCode="JN" term="%220410462%22">Nature</searchLink> [Nature] 2026 May; Vol. 653 (8115), pp. 879-887. <i>Date of Electronic Publication: </i>2026 Mar 25.
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