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A novel agarose-free, standardized generation and versatile ECM characterization of decellularized scaffolds from normal and fibrotic human lung tissue.

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Title: A novel agarose-free, standardized generation and versatile ECM characterization of decellularized scaffolds from normal and fibrotic human lung tissue.
Authors: Preuß EB; Institute of Pathology, Lung Research Group, Hannover Medical School, Hannover, Germany.; Biomedical Research in Endstage and Obstructive Lung Disease Hanover (BREATH), German Center for Lung Research (DZL), Hannover, Germany., Schröder LJ; Institute of Pathology, Lung Research Group, Hannover Medical School, Hannover, Germany.; Biomedical Research in Endstage and Obstructive Lung Disease Hanover (BREATH), German Center for Lung Research (DZL), Hannover, Germany., Hähner C; Institute of Pathology, Lung Research Group, Hannover Medical School, Hannover, Germany., von Bandemer JA; Institute of Pathology, Lung Research Group, Hannover Medical School, Hannover, Germany., Werlein C; Institute of Pathology, Lung Research Group, Hannover Medical School, Hannover, Germany., Schwarz EKJ; Institute of Pathology, Lung Research Group, Hannover Medical School, Hannover, Germany.; Biomedical Research in Endstage and Obstructive Lung Disease Hanover (BREATH), German Center for Lung Research (DZL), Hannover, Germany., Schubert S; Institute of Pathology, Lung Research Group, Hannover Medical School, Hannover, Germany., Schlüter H; Boehringer Ingelheim, Biberach an der Riß, Germany., Thomas MJ; Boehringer Ingelheim, Biberach an der Riß, Germany., Jonigk DD; Biomedical Research in Endstage and Obstructive Lung Disease Hanover (BREATH), German Center for Lung Research (DZL), Hannover, Germany.; Institute of Pathology, RWTH Aachen University/UKA, Aachen, Germany., Kamp JC; Biomedical Research in Endstage and Obstructive Lung Disease Hanover (BREATH), German Center for Lung Research (DZL), Hannover, Germany.; Department of Respiratory Medicine and Infectious Diseases, Hannover Medical School, Hannover, Germany., Kühnel MP; Biomedical Research in Endstage and Obstructive Lung Disease Hanover (BREATH), German Center for Lung Research (DZL), Hannover, Germany.; Institute of Pathology, RWTH Aachen University/UKA, Aachen, Germany.
Source: Frontiers in bioengineering and biotechnology [Front Bioeng Biotechnol] 2026 Mar 10; Vol. 14, pp. 1772891. Date of Electronic Publication: 2026 Mar 10 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101632513 Publication Model: eCollection Cited Medium: Print ISSN: 2296-4185 (Print) Linking ISSN: 22964185 NLM ISO Abbreviation: Front Bioeng Biotechnol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Preuß+EB%22">Preuß EB</searchLink>; Institute of Pathology, Lung Research Group, Hannover Medical School, Hannover, Germany.; Biomedical Research in Endstage and Obstructive Lung Disease Hanover (BREATH), German Center for Lung Research (DZL), Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Schröder+LJ%22">Schröder LJ</searchLink>; Institute of Pathology, Lung Research Group, Hannover Medical School, Hannover, Germany.; Biomedical Research in Endstage and Obstructive Lung Disease Hanover (BREATH), German Center for Lung Research (DZL), Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Hähner+C%22">Hähner C</searchLink>; Institute of Pathology, Lung Research Group, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22von+Bandemer+JA%22">von Bandemer JA</searchLink>; Institute of Pathology, Lung Research Group, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Werlein+C%22">Werlein C</searchLink>; Institute of Pathology, Lung Research Group, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Schwarz+EKJ%22">Schwarz EKJ</searchLink>; Institute of Pathology, Lung Research Group, Hannover Medical School, Hannover, Germany.; Biomedical Research in Endstage and Obstructive Lung Disease Hanover (BREATH), German Center for Lung Research (DZL), Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Schubert+S%22">Schubert S</searchLink>; Institute of Pathology, Lung Research Group, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Schlüter+H%22">Schlüter H</searchLink>; Boehringer Ingelheim, Biberach an der Riß, Germany.<br /><searchLink fieldCode="AU" term="%22Thomas+MJ%22">Thomas MJ</searchLink>; Boehringer Ingelheim, Biberach an der Riß, Germany.<br /><searchLink fieldCode="AU" term="%22Jonigk+DD%22">Jonigk DD</searchLink>; Biomedical Research in Endstage and Obstructive Lung Disease Hanover (BREATH), German Center for Lung Research (DZL), Hannover, Germany.; Institute of Pathology, RWTH Aachen University/UKA, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Kamp+JC%22">Kamp JC</searchLink>; Biomedical Research in Endstage and Obstructive Lung Disease Hanover (BREATH), German Center for Lung Research (DZL), Hannover, Germany.; Department of Respiratory Medicine and Infectious Diseases, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Kühnel+MP%22">Kühnel MP</searchLink>; Biomedical Research in Endstage and Obstructive Lung Disease Hanover (BREATH), German Center for Lung Research (DZL), Hannover, Germany.; Institute of Pathology, RWTH Aachen University/UKA, Aachen, Germany.
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              Text: 2026 Mar 10
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