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Machine learning-based combination of the central vein sign, cortical lesions and paramagnetic rim lesions: a web-based tool for the diagnosis of multiple sclerosis.

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Title: Machine learning-based combination of the central vein sign, cortical lesions and paramagnetic rim lesions: a web-based tool for the diagnosis of multiple sclerosis.
Authors: Wynen M; ICTEAM Institute, Université Catholique de Louvain, 1348 Louvain-la-Neuve, Belgium.; Neuroinflammation Imaging Lab (NIL), Université Catholique de Louvain, 1200 Brussels, Belgium., Vanden Bulcke C; ICTEAM Institute, Université Catholique de Louvain, 1348 Louvain-la-Neuve, Belgium.; Neuroinflammation Imaging Lab (NIL), Université Catholique de Louvain, 1200 Brussels, Belgium.; Department of Neurology, Cliniques Universitaires Saint-Luc (CUSL), Université Catholique de Louvain, 1200 Brussels, Belgium., Borrelli S; Neuroinflammation Imaging Lab (NIL), Université Catholique de Louvain, 1200 Brussels, Belgium.; Department of Neurology, Hôpital Erasme, Hôpital Universitaire de Bruxelles, Université Libre de Bruxelles, 1070 Brussels, Belgium., Gordaliza PM; CIBM Center for Biomedical Imaging, CH-1015 Lausanne, Switzerland.; Radiology Department, Lausanne University Hospital (CHUV) and University of Lausanne, CH-1011 Lausanne, Switzerland., Stölting A; Neuroinflammation Imaging Lab (NIL), Université Catholique de Louvain, 1200 Brussels, Belgium., Guisset F; Neuroinflammation Imaging Lab (NIL), Université Catholique de Louvain, 1200 Brussels, Belgium., Cordier C; ICTEAM Institute, Université Catholique de Louvain, 1348 Louvain-la-Neuve, Belgium., Martire MS; Neurology Unit, IRCCS San Raffaele Hospital, 20132 Milan, Italy., Tamanti A; Department of Neurosciences and Biomedicine and Movement, The Multiple Sclerosis Center of University Hospital of Verona, 37129 Verona, Italy., Macq B; ICTEAM Institute, Université Catholique de Louvain, 1348 Louvain-la-Neuve, Belgium., Sati P; Department of Neurology, Cedars-Sinai Medical Center, 90048 Los Angeles, CA, USA., Filippi M; Neurology Unit, IRCCS San Raffaele Hospital, 20132 Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.; Neuroimaging Research Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy., Calabrese M; Department of Neurosciences and Biomedicine and Movement, The Multiple Sclerosis Center of University Hospital of Verona, 37129 Verona, Italy., Absinta M; Experimental Neuropathology Lab, IRCCS Humanitas Research Institute, 20132 Milan, Italy.; Department of Biomedical Sciences, Humanitas University, 20072 Milan, Italy., Reich DS; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH), 20892 Bethesda, MD, USA., Bach Cuadra M; CIBM Center for Biomedical Imaging, CH-1015 Lausanne, Switzerland.; Radiology Department, Lausanne University Hospital (CHUV) and University of Lausanne, CH-1011 Lausanne, Switzerland., Maggi P; Neuroinflammation Imaging Lab (NIL), Université Catholique de Louvain, 1200 Brussels, Belgium.; Department of Neurology, Cliniques Universitaires Saint-Luc (CUSL), Université Catholique de Louvain, 1200 Brussels, Belgium.
Source: Brain communications [Brain Commun] 2026 Mar 11; Vol. 8 (2), pp. fcag079. Date of Electronic Publication: 2026 Mar 11 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101755125 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-1297 (Electronic) Linking ISSN: 26321297 NLM ISO Abbreviation: Brain Commun Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Machine learning-based combination of the central vein sign, cortical lesions and paramagnetic rim lesions: a web-based tool for the diagnosis of multiple sclerosis.
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  Data: <searchLink fieldCode="AU" term="%22Wynen+M%22">Wynen M</searchLink>; ICTEAM Institute, Université Catholique de Louvain, 1348 Louvain-la-Neuve, Belgium.; Neuroinflammation Imaging Lab (NIL), Université Catholique de Louvain, 1200 Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Vanden+Bulcke+C%22">Vanden Bulcke C</searchLink>; ICTEAM Institute, Université Catholique de Louvain, 1348 Louvain-la-Neuve, Belgium.; Neuroinflammation Imaging Lab (NIL), Université Catholique de Louvain, 1200 Brussels, Belgium.; Department of Neurology, Cliniques Universitaires Saint-Luc (CUSL), Université Catholique de Louvain, 1200 Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Borrelli+S%22">Borrelli S</searchLink>; Neuroinflammation Imaging Lab (NIL), Université Catholique de Louvain, 1200 Brussels, Belgium.; Department of Neurology, Hôpital Erasme, Hôpital Universitaire de Bruxelles, Université Libre de Bruxelles, 1070 Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Gordaliza+PM%22">Gordaliza PM</searchLink>; CIBM Center for Biomedical Imaging, CH-1015 Lausanne, Switzerland.; Radiology Department, Lausanne University Hospital (CHUV) and University of Lausanne, CH-1011 Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Stölting+A%22">Stölting A</searchLink>; Neuroinflammation Imaging Lab (NIL), Université Catholique de Louvain, 1200 Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Guisset+F%22">Guisset F</searchLink>; Neuroinflammation Imaging Lab (NIL), Université Catholique de Louvain, 1200 Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Cordier+C%22">Cordier C</searchLink>; ICTEAM Institute, Université Catholique de Louvain, 1348 Louvain-la-Neuve, Belgium.<br /><searchLink fieldCode="AU" term="%22Martire+MS%22">Martire MS</searchLink>; Neurology Unit, IRCCS San Raffaele Hospital, 20132 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Tamanti+A%22">Tamanti A</searchLink>; Department of Neurosciences and Biomedicine and Movement, The Multiple Sclerosis Center of University Hospital of Verona, 37129 Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Macq+B%22">Macq B</searchLink>; ICTEAM Institute, Université Catholique de Louvain, 1348 Louvain-la-Neuve, Belgium.<br /><searchLink fieldCode="AU" term="%22Sati+P%22">Sati P</searchLink>; Department of Neurology, Cedars-Sinai Medical Center, 90048 Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Filippi+M%22">Filippi M</searchLink>; Neurology Unit, IRCCS San Raffaele Hospital, 20132 Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.; Neuroimaging Research Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Calabrese+M%22">Calabrese M</searchLink>; Department of Neurosciences and Biomedicine and Movement, The Multiple Sclerosis Center of University Hospital of Verona, 37129 Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Absinta+M%22">Absinta M</searchLink>; Experimental Neuropathology Lab, IRCCS Humanitas Research Institute, 20132 Milan, Italy.; Department of Biomedical Sciences, Humanitas University, 20072 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Reich+DS%22">Reich DS</searchLink>; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH), 20892 Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Bach+Cuadra+M%22">Bach Cuadra M</searchLink>; CIBM Center for Biomedical Imaging, CH-1015 Lausanne, Switzerland.; Radiology Department, Lausanne University Hospital (CHUV) and University of Lausanne, CH-1011 Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Maggi+P%22">Maggi P</searchLink>; Neuroinflammation Imaging Lab (NIL), Université Catholique de Louvain, 1200 Brussels, Belgium.; Department of Neurology, Cliniques Universitaires Saint-Luc (CUSL), Université Catholique de Louvain, 1200 Brussels, Belgium.
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  Data: <searchLink fieldCode="JN" term="%22101755125%22">Brain communications</searchLink> [Brain Commun] 2026 Mar 11; Vol. 8 (2), pp. fcag079. <i>Date of Electronic Publication: </i>2026 Mar 11 (<i>Print Publication: </i>2026).
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