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The role of large immune complexes in anti-drug antibody development: a case study of anti-SARS-CoV-2 antibody therapeutics and co-administered mRNA vaccine.

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Title: The role of large immune complexes in anti-drug antibody development: a case study of anti-SARS-CoV-2 antibody therapeutics and co-administered mRNA vaccine.
Authors: Irvin SC; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, United States., Wang Z; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, United States., Ganguly S; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, United States., Choudhary D; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, United States., Kanagaraj M; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, United States., Liu N; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, United States., Isa F; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, United States., He ZW; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, United States., Yan H; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, United States., Casullo VM; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, United States., Turner KC; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, United States., Davis JD; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, United States., Rosconi MP; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, United States., Torri A; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, United States., Partridge MA; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, United States.
Source: Frontiers in immunology [Front Immunol] 2026 Mar 10; Vol. 17, pp. 1769163. Date of Electronic Publication: 2026 Mar 10 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Mar 10; Vol. 17, pp. 1769163. <i>Date of Electronic Publication: </i>2026 Mar 10 (<i>Print Publication: </i>2026).
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