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Highly Active Cu14 Cluster Precisely Activates Autophagy Inhibitor to Amplify Cuproptosis Immunotherapy.

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Title: Highly Active Cu14 Cluster Precisely Activates Autophagy Inhibitor to Amplify Cuproptosis Immunotherapy.
Authors: Zang QX; State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Henan International Joint Laboratory of Tumor Theranostic Cluster Materials, College of Chemistry, Zhengzhou University, Zhengzhou, Henan, P. R. China.; Tianjian Laboratory of Advanced Biomedical Sciences, Institute of Advanced Biomedical Sciences, Zhengzhou University, Zhengzhou, Henan, P. R. China., Chen WT; State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Henan International Joint Laboratory of Tumor Theranostic Cluster Materials, College of Chemistry, Zhengzhou University, Zhengzhou, Henan, P. R. China.; Tianjian Laboratory of Advanced Biomedical Sciences, Institute of Advanced Biomedical Sciences, Zhengzhou University, Zhengzhou, Henan, P. R. China., Shen YY; State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Henan International Joint Laboratory of Tumor Theranostic Cluster Materials, College of Chemistry, Zhengzhou University, Zhengzhou, Henan, P. R. China.; Tianjian Laboratory of Advanced Biomedical Sciences, Institute of Advanced Biomedical Sciences, Zhengzhou University, Zhengzhou, Henan, P. R. China., Wang ZY; State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Henan International Joint Laboratory of Tumor Theranostic Cluster Materials, College of Chemistry, Zhengzhou University, Zhengzhou, Henan, P. R. China.; Tianjian Laboratory of Advanced Biomedical Sciences, Institute of Advanced Biomedical Sciences, Zhengzhou University, Zhengzhou, Henan, P. R. China., Li K; State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Henan International Joint Laboratory of Tumor Theranostic Cluster Materials, College of Chemistry, Zhengzhou University, Zhengzhou, Henan, P. R. China.; Tianjian Laboratory of Advanced Biomedical Sciences, Institute of Advanced Biomedical Sciences, Zhengzhou University, Zhengzhou, Henan, P. R. China., Zhao X; State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Henan International Joint Laboratory of Tumor Theranostic Cluster Materials, College of Chemistry, Zhengzhou University, Zhengzhou, Henan, P. R. China.; Tianjian Laboratory of Advanced Biomedical Sciences, Institute of Advanced Biomedical Sciences, Zhengzhou University, Zhengzhou, Henan, P. R. China., Sang Y; State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Henan International Joint Laboratory of Tumor Theranostic Cluster Materials, College of Chemistry, Zhengzhou University, Zhengzhou, Henan, P. R. China.; Tianjian Laboratory of Advanced Biomedical Sciences, Institute of Advanced Biomedical Sciences, Zhengzhou University, Zhengzhou, Henan, P. R. China., Chen X; Shandong Provincial Key Laboratory of Precision Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, P. R. China., Zang SQ; State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Henan International Joint Laboratory of Tumor Theranostic Cluster Materials, College of Chemistry, Zhengzhou University, Zhengzhou, Henan, P. R. China.; Tianjian Laboratory of Advanced Biomedical Sciences, Institute of Advanced Biomedical Sciences, Zhengzhou University, Zhengzhou, Henan, P. R. China.
Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2026 Jun; Vol. 13 (33), pp. e17021. Date of Electronic Publication: 2026 Mar 26.
Publication Type: Journal Article
Journal Info: Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844 (Electronic) Linking ISSN: 21983844 NLM ISO Abbreviation: Adv Sci (Weinh) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Highly Active Cu<subscript>14</subscript> Cluster Precisely Activates Autophagy Inhibitor to Amplify Cuproptosis Immunotherapy.
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  Data: <searchLink fieldCode="AU" term="%22Zang+QX%22">Zang QX</searchLink>; State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Henan International Joint Laboratory of Tumor Theranostic Cluster Materials, College of Chemistry, Zhengzhou University, Zhengzhou, Henan, P. R. China.; Tianjian Laboratory of Advanced Biomedical Sciences, Institute of Advanced Biomedical Sciences, Zhengzhou University, Zhengzhou, Henan, P. R. China.<br /><searchLink fieldCode="AU" term="%22Chen+WT%22">Chen WT</searchLink>; State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Henan International Joint Laboratory of Tumor Theranostic Cluster Materials, College of Chemistry, Zhengzhou University, Zhengzhou, Henan, P. R. China.; Tianjian Laboratory of Advanced Biomedical Sciences, Institute of Advanced Biomedical Sciences, Zhengzhou University, Zhengzhou, Henan, P. R. China.<br /><searchLink fieldCode="AU" term="%22Shen+YY%22">Shen YY</searchLink>; State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Henan International Joint Laboratory of Tumor Theranostic Cluster Materials, College of Chemistry, Zhengzhou University, Zhengzhou, Henan, P. R. China.; Tianjian Laboratory of Advanced Biomedical Sciences, Institute of Advanced Biomedical Sciences, Zhengzhou University, Zhengzhou, Henan, P. R. China.<br /><searchLink fieldCode="AU" term="%22Wang+ZY%22">Wang ZY</searchLink>; State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Henan International Joint Laboratory of Tumor Theranostic Cluster Materials, College of Chemistry, Zhengzhou University, Zhengzhou, Henan, P. R. China.; Tianjian Laboratory of Advanced Biomedical Sciences, Institute of Advanced Biomedical Sciences, Zhengzhou University, Zhengzhou, Henan, P. R. China.<br /><searchLink fieldCode="AU" term="%22Li+K%22">Li K</searchLink>; State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Henan International Joint Laboratory of Tumor Theranostic Cluster Materials, College of Chemistry, Zhengzhou University, Zhengzhou, Henan, P. R. China.; Tianjian Laboratory of Advanced Biomedical Sciences, Institute of Advanced Biomedical Sciences, Zhengzhou University, Zhengzhou, Henan, P. R. China.<br /><searchLink fieldCode="AU" term="%22Zhao+X%22">Zhao X</searchLink>; State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Henan International Joint Laboratory of Tumor Theranostic Cluster Materials, College of Chemistry, Zhengzhou University, Zhengzhou, Henan, P. R. China.; Tianjian Laboratory of Advanced Biomedical Sciences, Institute of Advanced Biomedical Sciences, Zhengzhou University, Zhengzhou, Henan, P. R. China.<br /><searchLink fieldCode="AU" term="%22Sang+Y%22">Sang Y</searchLink>; State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Henan International Joint Laboratory of Tumor Theranostic Cluster Materials, College of Chemistry, Zhengzhou University, Zhengzhou, Henan, P. R. China.; Tianjian Laboratory of Advanced Biomedical Sciences, Institute of Advanced Biomedical Sciences, Zhengzhou University, Zhengzhou, Henan, P. R. China.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; Shandong Provincial Key Laboratory of Precision Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, P. R. China.<br /><searchLink fieldCode="AU" term="%22Zang+SQ%22">Zang SQ</searchLink>; State Key Laboratory of Metabolic Dysregulation & Prevention and Treatment of Esophageal Cancer, Henan International Joint Laboratory of Tumor Theranostic Cluster Materials, College of Chemistry, Zhengzhou University, Zhengzhou, Henan, P. R. China.; Tianjian Laboratory of Advanced Biomedical Sciences, Institute of Advanced Biomedical Sciences, Zhengzhou University, Zhengzhou, Henan, P. R. China.
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  Data: <searchLink fieldCode="JN" term="%22101664569%22">Advanced science (Weinheim, Baden-Wurttemberg, Germany)</searchLink> [Adv Sci (Weinh)] 2026 Jun; Vol. 13 (33), pp. e17021. <i>Date of Electronic Publication: </i>2026 Mar 26.
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        Value: 10.1002/advs.202517021
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        Text: English
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        StartPage: e17021
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      – TitleFull: Highly Active Cu14 Cluster Precisely Activates Autophagy Inhibitor to Amplify Cuproptosis Immunotherapy.
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            NameFull: Zang QX
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              M: 06
              Text: 2026 Jun
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              Y: 2026
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