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Muscle atrophy after ACL reconstruction involves molecular mechanisms beyond unloading.

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Title: Muscle atrophy after ACL reconstruction involves molecular mechanisms beyond unloading.
Authors: Keeble AR; Center for Muscle Biology, University of Kentucky, Lexington, Kentucky, United States.; Department of Athletic Training and Clinical Nutrition, College of Health Sciences, University of Kentucky, Lexington, Kentucky, United States., Gonzalez-Velez S; Center for Muscle Biology, University of Kentucky, Lexington, Kentucky, United States.; Department of Athletic Training and Clinical Nutrition, College of Health Sciences, University of Kentucky, Lexington, Kentucky, United States.; Department of Physiology, College of Medicine, University of Kentucky, Lexington, Kentucky, United States., Thomas NT; Center for Muscle Biology, University of Kentucky, Lexington, Kentucky, United States.; Department of Physiology, College of Medicine, University of Kentucky, Lexington, Kentucky, United States., Owen AM; Center for Muscle Biology, University of Kentucky, Lexington, Kentucky, United States.; Department of Physical Therapy, College of Health Sciences, University of Kentucky, Lexington, Kentucky, United States., Stone AV; Department of Orthopaedic Surgery and Sports Medicine, College of Medicine, University of Kentucky, Lexington, Kentucky, United States., Johnson DL; Department of Orthopaedic Surgery and Sports Medicine, College of Medicine, University of Kentucky, Lexington, Kentucky, United States., Candia J; Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland, United States., Ferrucci L; Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland, United States., Narici M; Department of Biomedical Sciences, University of Padua, Padua, Italy.; CIR-MYO Myology Center, University of Padua, Padua, Italy., Dupont-Versteegden EE; Center for Muscle Biology, University of Kentucky, Lexington, Kentucky, United States.; Department of Physical Therapy, College of Health Sciences, University of Kentucky, Lexington, Kentucky, United States., Noehren B; Center for Muscle Biology, University of Kentucky, Lexington, Kentucky, United States.; Department of Physical Therapy, College of Health Sciences, University of Kentucky, Lexington, Kentucky, United States.; Department of Orthopaedic Surgery and Sports Medicine, College of Medicine, University of Kentucky, Lexington, Kentucky, United States., Franchi MV; Department of Biomedical Sciences, University of Padua, Padua, Italy.; CIR-MYO Myology Center, University of Padua, Padua, Italy., Fry CS; Center for Muscle Biology, University of Kentucky, Lexington, Kentucky, United States.; Department of Athletic Training and Clinical Nutrition, College of Health Sciences, University of Kentucky, Lexington, Kentucky, United States.
Source: Journal of applied physiology (Bethesda, Md. : 1985) [J Appl Physiol (1985)] 2026 Apr 01; Vol. 140 (4), pp. 1123-1130. Date of Electronic Publication: 2026 Mar 26.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 8502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1601 (Electronic) Linking ISSN: 01617567 NLM ISO Abbreviation: J Appl Physiol (1985) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Keeble+AR%22">Keeble AR</searchLink>; Center for Muscle Biology, University of Kentucky, Lexington, Kentucky, United States.; Department of Athletic Training and Clinical Nutrition, College of Health Sciences, University of Kentucky, Lexington, Kentucky, United States.<br /><searchLink fieldCode="AU" term="%22Gonzalez-Velez+S%22">Gonzalez-Velez S</searchLink>; Center for Muscle Biology, University of Kentucky, Lexington, Kentucky, United States.; Department of Athletic Training and Clinical Nutrition, College of Health Sciences, University of Kentucky, Lexington, Kentucky, United States.; Department of Physiology, College of Medicine, University of Kentucky, Lexington, Kentucky, United States.<br /><searchLink fieldCode="AU" term="%22Thomas+NT%22">Thomas NT</searchLink>; Center for Muscle Biology, University of Kentucky, Lexington, Kentucky, United States.; Department of Physiology, College of Medicine, University of Kentucky, Lexington, Kentucky, United States.<br /><searchLink fieldCode="AU" term="%22Owen+AM%22">Owen AM</searchLink>; Center for Muscle Biology, University of Kentucky, Lexington, Kentucky, United States.; Department of Physical Therapy, College of Health Sciences, University of Kentucky, Lexington, Kentucky, United States.<br /><searchLink fieldCode="AU" term="%22Stone+AV%22">Stone AV</searchLink>; Department of Orthopaedic Surgery and Sports Medicine, College of Medicine, University of Kentucky, Lexington, Kentucky, United States.<br /><searchLink fieldCode="AU" term="%22Johnson+DL%22">Johnson DL</searchLink>; Department of Orthopaedic Surgery and Sports Medicine, College of Medicine, University of Kentucky, Lexington, Kentucky, United States.<br /><searchLink fieldCode="AU" term="%22Candia+J%22">Candia J</searchLink>; Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland, United States.<br /><searchLink fieldCode="AU" term="%22Ferrucci+L%22">Ferrucci L</searchLink>; Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland, United States.<br /><searchLink fieldCode="AU" term="%22Narici+M%22">Narici M</searchLink>; Department of Biomedical Sciences, University of Padua, Padua, Italy.; CIR-MYO Myology Center, University of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Dupont-Versteegden+EE%22">Dupont-Versteegden EE</searchLink>; Center for Muscle Biology, University of Kentucky, Lexington, Kentucky, United States.; Department of Physical Therapy, College of Health Sciences, University of Kentucky, Lexington, Kentucky, United States.<br /><searchLink fieldCode="AU" term="%22Noehren+B%22">Noehren B</searchLink>; Center for Muscle Biology, University of Kentucky, Lexington, Kentucky, United States.; Department of Physical Therapy, College of Health Sciences, University of Kentucky, Lexington, Kentucky, United States.; Department of Orthopaedic Surgery and Sports Medicine, College of Medicine, University of Kentucky, Lexington, Kentucky, United States.<br /><searchLink fieldCode="AU" term="%22Franchi+MV%22">Franchi MV</searchLink>; Department of Biomedical Sciences, University of Padua, Padua, Italy.; CIR-MYO Myology Center, University of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Fry+CS%22">Fry CS</searchLink>; Center for Muscle Biology, University of Kentucky, Lexington, Kentucky, United States.; Department of Athletic Training and Clinical Nutrition, College of Health Sciences, University of Kentucky, Lexington, Kentucky, United States.
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