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Multiomic and Longitudinal Dissection of Immune Dynamics Associated with Parkinsonism after Ciltacabtagene Autoleucel Therapy.

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Title: Multiomic and Longitudinal Dissection of Immune Dynamics Associated with Parkinsonism after Ciltacabtagene Autoleucel Therapy.
Authors: Kadel SK; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany.; Helmholtz-Institute for RNA-based Infection Research, Helmholtz Centre for Infection Research (HZI), Würzburg, Germany., Scheller L; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany.; Interdisciplinary Center for Clinical Research (IZKF), University Hospital of Würzburg, Würzburg, Germany.; Department of Internal Medicine II, Chair of Cellular Immunotherapy, University Hospital of Würzburg, Würzburg, Germany., Leipold AM; Helmholtz-Institute for RNA-based Infection Research, Helmholtz Centre for Infection Research (HZI), Würzburg, Germany.; Institute of Molecular Infection Biology (IMIB), University of Würzburg, Würzburg, Germany., Krammer T; Helmholtz-Institute for RNA-based Infection Research, Helmholtz Centre for Infection Research (HZI), Würzburg, Germany., Raskó T; Department of Internal Medicine II, Chair of Cellular Immunotherapy, University Hospital of Würzburg, Würzburg, Germany., Alb M; Department of Internal Medicine II, Chair of Cellular Immunotherapy, University Hospital of Würzburg, Würzburg, Germany., Weis P; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany., Leberzammer M; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany., Schmitt F; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany., Stetter C; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany., Tamamushi Y; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany., Köck A; Helmholtz-Institute for RNA-based Infection Research, Helmholtz Centre for Infection Research (HZI), Würzburg, Germany., Köberle P; Department of Neurology, University Hospital of Würzburg, Würzburg, Germany., Reich M; Department of Neurology, University Hospital of Würzburg, Würzburg, Germany., Musacchio T; Department of Neurology, University Hospital of Würzburg, Würzburg, Germany., Doppler K; Department of Neurology, University Hospital of Würzburg, Würzburg, Germany., Sommer C; Department of Neurology, University Hospital of Würzburg, Würzburg, Germany., Cebulla N; Department of Neurology, University Hospital of Würzburg, Würzburg, Germany., McFleder R; Department of Neurology, University Hospital of Würzburg, Würzburg, Germany., Ip CW; Department of Neurology, University Hospital of Würzburg, Würzburg, Germany., Volkmann J; Department of Neurology, University Hospital of Würzburg, Würzburg, Germany., Kallius M; Department of Nuclear Medicine, University Hospital of Würzburg, Würzburg, Germany., Serfling SE; Department of Nuclear Medicine, University Hospital of Würzburg, Würzburg, Germany., Hartrampf PE; Department of Nuclear Medicine, University Hospital of Würzburg, Würzburg, Germany., Buck AK; Department of Nuclear Medicine, University Hospital of Würzburg, Würzburg, Germany., Pande A; Berlin Institute for Medical Systems Biology (BIMSB), Berlin, Germany., Löffler D; Fraunhofer Institute for Cell Therapy and Immunology , Leipzig, Germany.; Fraunhofer Cluster of Excellence Immune-Mediated Diseases (CIMD), Leipzig, Germany., Gernert M; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany., Duell J; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany., Topp MS; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany., Mersi J; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany., Waldschmidt J; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany., Einsele H; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany., Hudecek M; Department of Internal Medicine II, Chair of Cellular Immunotherapy, University Hospital of Würzburg, Würzburg, Germany., Saliba AE; Helmholtz-Institute for RNA-based Infection Research, Helmholtz Centre for Infection Research (HZI), Würzburg, Germany.; Institute of Molecular Infection Biology (IMIB), University of Würzburg, Würzburg, Germany.; Cluster for Nucleic Acid Sciences and Technologies - NUCLEATE, Würzburg, Germany., Rasche L; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany., Kortüm KM; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany.
Source: Blood cancer discovery [Blood Cancer Discov] 2026 Jul 01; Vol. 7 (4), pp. 544-557.
Publication Type: Journal Article; Case Reports
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101764786 Publication Model: Print Cited Medium: Internet ISSN: 2643-3249 (Electronic) Linking ISSN: 26433230 NLM ISO Abbreviation: Blood Cancer Discov Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Kadel+SK%22">Kadel SK</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany.; Helmholtz-Institute for RNA-based Infection Research, Helmholtz Centre for Infection Research (HZI), Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Scheller+L%22">Scheller L</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany.; Interdisciplinary Center for Clinical Research (IZKF), University Hospital of Würzburg, Würzburg, Germany.; Department of Internal Medicine II, Chair of Cellular Immunotherapy, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Leipold+AM%22">Leipold AM</searchLink>; Helmholtz-Institute for RNA-based Infection Research, Helmholtz Centre for Infection Research (HZI), Würzburg, Germany.; Institute of Molecular Infection Biology (IMIB), University of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Krammer+T%22">Krammer T</searchLink>; Helmholtz-Institute for RNA-based Infection Research, Helmholtz Centre for Infection Research (HZI), Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Raskó+T%22">Raskó T</searchLink>; Department of Internal Medicine II, Chair of Cellular Immunotherapy, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Alb+M%22">Alb M</searchLink>; Department of Internal Medicine II, Chair of Cellular Immunotherapy, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Weis+P%22">Weis P</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Leberzammer+M%22">Leberzammer M</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schmitt+F%22">Schmitt F</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Stetter+C%22">Stetter C</searchLink>; 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Department of Neurology, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Cebulla+N%22">Cebulla N</searchLink>; Department of Neurology, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22McFleder+R%22">McFleder R</searchLink>; Department of Neurology, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Ip+CW%22">Ip CW</searchLink>; Department of Neurology, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Volkmann+J%22">Volkmann J</searchLink>; Department of Neurology, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Kallius+M%22">Kallius M</searchLink>; Department of Nuclear Medicine, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Serfling+SE%22">Serfling SE</searchLink>; Department of Nuclear Medicine, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Hartrampf+PE%22">Hartrampf PE</searchLink>; Department of Nuclear Medicine, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Buck+AK%22">Buck AK</searchLink>; Department of Nuclear Medicine, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Pande+A%22">Pande A</searchLink>; Berlin Institute for Medical Systems Biology (BIMSB), Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Löffler+D%22">Löffler D</searchLink>; Fraunhofer Institute for Cell Therapy and Immunology , Leipzig, Germany.; Fraunhofer Cluster of Excellence Immune-Mediated Diseases (CIMD), Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Gernert+M%22">Gernert M</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Duell+J%22">Duell J</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Topp+MS%22">Topp MS</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Mersi+J%22">Mersi J</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Waldschmidt+J%22">Waldschmidt J</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Einsele+H%22">Einsele H</searchLink>; Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Hudecek+M%22">Hudecek M</searchLink>; Department of Internal Medicine II, Chair of Cellular Immunotherapy, University Hospital of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Saliba+AE%22">Saliba AE</searchLink>; Helmholtz-Institute for RNA-based Infection Research, Helmholtz Centre for Infection Research (HZI), Würzburg, Germany.; Institute of Molecular Infection Biology (IMIB), University of Würzburg, Würzburg, Germany.; 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