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A Surfactant Cocktail Overcomes Air-Water Interface Artifacts in Single-Particle CryoEM.

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Title: A Surfactant Cocktail Overcomes Air-Water Interface Artifacts in Single-Particle CryoEM.
Authors: Enos SE; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093., Cook BD; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093., Rahmani H; Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, CA 92037., Narehood SM; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093., Li Y; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093., Kuschnerus IC; University of California, San Diego Cryo-EM Facility, University of California, San Diego, La Jolla, CA 92093., Redford TH; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093., Dukakis P; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093., Ji D; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093., Bachochin MJ; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093., Grotjahn DA; Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, CA 92037., Herzik MA Jr; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Mar 18. Date of Electronic Publication: 2026 Mar 18.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Enos+SE%22">Enos SE</searchLink>; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093.<br /><searchLink fieldCode="AU" term="%22Cook+BD%22">Cook BD</searchLink>; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093.<br /><searchLink fieldCode="AU" term="%22Rahmani+H%22">Rahmani H</searchLink>; Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, CA 92037.<br /><searchLink fieldCode="AU" term="%22Narehood+SM%22">Narehood SM</searchLink>; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093.<br /><searchLink fieldCode="AU" term="%22Kuschnerus+IC%22">Kuschnerus IC</searchLink>; University of California, San Diego Cryo-EM Facility, University of California, San Diego, La Jolla, CA 92093.<br /><searchLink fieldCode="AU" term="%22Redford+TH%22">Redford TH</searchLink>; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093.<br /><searchLink fieldCode="AU" term="%22Dukakis+P%22">Dukakis P</searchLink>; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093.<br /><searchLink fieldCode="AU" term="%22Ji+D%22">Ji D</searchLink>; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093.<br /><searchLink fieldCode="AU" term="%22Bachochin+MJ%22">Bachochin MJ</searchLink>; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093.<br /><searchLink fieldCode="AU" term="%22Grotjahn+DA%22">Grotjahn DA</searchLink>; Department of Integrative Structural and Computational Biology, Scripps Research, La Jolla, CA 92037.<br /><searchLink fieldCode="AU" term="%22Herzik+MA+Jr%22">Herzik MA Jr</searchLink>; Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093.
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2026 Mar 18. <i>Date of Electronic Publication: </i>2026 Mar 18.
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