An epigenetic bifunctional that toggles between transactivation and repression.

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Title: An epigenetic bifunctional that toggles between transactivation and repression.
Authors: Sadagopan A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Carson M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Zamurs EJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Srikonda S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Weiss CN; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute.; Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA., Bond MJ; Department of Pediatric Oncology, Dana-Farber Cancer Institute.; Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA., Sodhi A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Donovan KA; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA., Ryan JK; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Fischer ES; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA., Stegmaier K; Department of Pediatric Oncology, Dana-Farber Cancer Institute.; Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Viswanathan SR; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ebert BL; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Gibson WJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Mar 20. Date of Electronic Publication: 2026 Mar 20.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: An epigenetic bifunctional that toggles between transactivation and repression.
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  Data: <searchLink fieldCode="AU" term="%22Sadagopan+A%22">Sadagopan A</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Carson+M%22">Carson M</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Zamurs+EJ%22">Zamurs EJ</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Srikonda+S%22">Srikonda S</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Weiss+CN%22">Weiss CN</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute.; Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bond+MJ%22">Bond MJ</searchLink>; Department of Pediatric Oncology, Dana-Farber Cancer Institute.; Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sodhi+A%22">Sodhi A</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Donovan+KA%22">Donovan KA</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ryan+JK%22">Ryan JK</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Fischer+ES%22">Fischer ES</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Stegmaier+K%22">Stegmaier K</searchLink>; Department of Pediatric Oncology, Dana-Farber Cancer Institute.; Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Viswanathan+SR%22">Viswanathan SR</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ebert+BL%22">Ebert BL</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Gibson+WJ%22">Gibson WJ</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
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        Value: 10.64898/2026.03.17.712509
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              Text: 2026 Mar 20
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