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Diverse high-fat diets drive multi-omic reprogramming that persists after dietary reversal.

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Title: Diverse high-fat diets drive multi-omic reprogramming that persists after dietary reversal.
Authors: Van Camp AG; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Park J; Department of Systems and Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., Ozcelik E; Department of Systems and Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., Eskiocak O; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA; Graduate Program in Genetics, Stony Brook University, Stony Brook, NY, USA., Ozler KA; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Papciak K; Cell Biology Program, Sloan Kettering Institute, New York, NY, USA., Subhash S; Department of Biosciences and Bioengineering, Indian Institute of Technology Jammu, Jammu, India., Alwaseem H; Rockefeller University, New York, NY 10065, USA., Ergin I; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Chung C; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Shah V; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Yueh B; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Alici A; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Fein MR; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Durmaz C; Department of Physiology and Biophysics and the WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, NY, USA., Mozsary C; Department of Physiology and Biophysics and the WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, NY, USA., Kilic E; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Damle N; Department of Physiology and Biophysics and the WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, NY, USA., Najjar D; Department of Physiology and Biophysics and the WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, NY, USA., Nelson TM; Department of Systems and Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., Ryon KA; Department of Physiology and Biophysics and the WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, NY, USA., Butler DJ; Department of Physiology and Biophysics and the WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, NY, USA., Patel CJ; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Thaiss CA; Department of Pathology, Stanford University, Stanford, CA, USA., Birsoy K; Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY, USA., Mason CE; Department of Physiology and Biophysics and the WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, NY, USA., Meydan C; Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Tierney BT; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.; The Two Frontiers Project, Fort Collins, CO, USA., Beyaz S; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Apr 23. Date of Electronic Publication: 2026 Apr 23.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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PubType: Academic Journal
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  Data: Diverse high-fat diets drive multi-omic reprogramming that persists after dietary reversal.
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  Data: <searchLink fieldCode="AU" term="%22Van+Camp+AG%22">Van Camp AG</searchLink>; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Park+J%22">Park J</searchLink>; Department of Systems and Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ozcelik+E%22">Ozcelik E</searchLink>; Department of Systems and Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Eskiocak+O%22">Eskiocak O</searchLink>; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA; Graduate Program in Genetics, Stony Brook University, Stony Brook, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ozler+KA%22">Ozler KA</searchLink>; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.<br /><searchLink fieldCode="AU" term="%22Papciak+K%22">Papciak K</searchLink>; Cell Biology Program, Sloan Kettering Institute, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Subhash+S%22">Subhash S</searchLink>; Department of Biosciences and Bioengineering, Indian Institute of Technology Jammu, Jammu, India.<br /><searchLink fieldCode="AU" term="%22Alwaseem+H%22">Alwaseem H</searchLink>; Rockefeller University, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Ergin+I%22">Ergin I</searchLink>; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.<br /><searchLink fieldCode="AU" term="%22Chung+C%22">Chung C</searchLink>; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.<br /><searchLink fieldCode="AU" term="%22Shah+V%22">Shah V</searchLink>; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.<br /><searchLink fieldCode="AU" term="%22Yueh+B%22">Yueh B</searchLink>; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.<br /><searchLink fieldCode="AU" term="%22Alici+A%22">Alici A</searchLink>; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.<br /><searchLink fieldCode="AU" term="%22Fein+MR%22">Fein MR</searchLink>; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.<br /><searchLink fieldCode="AU" term="%22Durmaz+C%22">Durmaz C</searchLink>; Department of Physiology and Biophysics and the WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, NY, USA.<br /><searchLink fieldCode="AU" term="%22Mozsary+C%22">Mozsary C</searchLink>; Department of Physiology and Biophysics and the WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, NY, USA.<br /><searchLink fieldCode="AU" term="%22Kilic+E%22">Kilic E</searchLink>; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.<br /><searchLink fieldCode="AU" term="%22Damle+N%22">Damle N</searchLink>; Department of Physiology and Biophysics and the WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, NY, USA.<br /><searchLink fieldCode="AU" term="%22Najjar+D%22">Najjar D</searchLink>; Department of Physiology and Biophysics and the WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, NY, USA.<br /><searchLink fieldCode="AU" term="%22Nelson+TM%22">Nelson TM</searchLink>; Department of Systems and Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ryon+KA%22">Ryon KA</searchLink>; Department of Physiology and Biophysics and the WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, NY, USA.<br /><searchLink fieldCode="AU" term="%22Butler+DJ%22">Butler DJ</searchLink>; Department of Physiology and Biophysics and the WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, NY, USA.<br /><searchLink fieldCode="AU" term="%22Patel+CJ%22">Patel CJ</searchLink>; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Thaiss+CA%22">Thaiss CA</searchLink>; Department of Pathology, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Birsoy+K%22">Birsoy K</searchLink>; Laboratory of Metabolic Regulation and Genetics, The Rockefeller University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Mason+CE%22">Mason CE</searchLink>; Department of Physiology and Biophysics and the WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, NY, USA.<br /><searchLink fieldCode="AU" term="%22Meydan+C%22">Meydan C</searchLink>; Department of Medicine, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Tierney+BT%22">Tierney BT</searchLink>; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.; The Two Frontiers Project, Fort Collins, CO, USA.<br /><searchLink fieldCode="AU" term="%22Beyaz+S%22">Beyaz S</searchLink>; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
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