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A CRISPR-Cas9 screen Reveals STEEP1 as a Key Host Dependency Factor for Epstein-Barr Virus Latent Membrane Protein 1 Trafficking and Signaling.

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Title: A CRISPR-Cas9 screen Reveals STEEP1 as a Key Host Dependency Factor for Epstein-Barr Virus Latent Membrane Protein 1 Trafficking and Signaling.
Authors: Li SF; Division of Infectious Diseases, Department of Medicine, Mass General Brigham Hospital, Boston, Massachusetts.; Center for Integrated Solutions for Infectious Diseases, Broad Institute, Cambridge, Massachusetts.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts., Sun Y; Division of Infectious Diseases, Department of Medicine, Mass General Brigham Hospital, Boston, Massachusetts.; Center for Integrated Solutions for Infectious Diseases, Broad Institute, Cambridge, Massachusetts.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts., Liao Y; Division of Infectious Diseases, Department of Medicine, Mass General Brigham Hospital, Boston, Massachusetts.; Center for Integrated Solutions for Infectious Diseases, Broad Institute, Cambridge, Massachusetts.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts., Zhong L; Division of Infectious Diseases, Department of Medicine, Mass General Brigham Hospital, Boston, Massachusetts.; Center for Integrated Solutions for Infectious Diseases, Broad Institute, Cambridge, Massachusetts.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts., Burton EM; Division of Infectious Diseases, Department of Medicine, Mass General Brigham Hospital, Boston, Massachusetts.; Center for Integrated Solutions for Infectious Diseases, Broad Institute, Cambridge, Massachusetts.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts., Mitra B; Division of Infectious Diseases, Department of Medicine, Mass General Brigham Hospital, Boston, Massachusetts.; Center for Integrated Solutions for Infectious Diseases, Broad Institute, Cambridge, Massachusetts.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts., Gewurz BE; Division of Infectious Diseases, Department of Medicine, Mass General Brigham Hospital, Boston, Massachusetts.; Center for Integrated Solutions for Infectious Diseases, Broad Institute, Cambridge, Massachusetts.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Mar 20. Date of Electronic Publication: 2026 Mar 20.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: A CRISPR-Cas9 screen Reveals STEEP1 as a Key Host Dependency Factor for Epstein-Barr Virus Latent Membrane Protein 1 Trafficking and Signaling.
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  Data: <searchLink fieldCode="AU" term="%22Li+SF%22">Li SF</searchLink>; Division of Infectious Diseases, Department of Medicine, Mass General Brigham Hospital, Boston, Massachusetts.; Center for Integrated Solutions for Infectious Diseases, Broad Institute, Cambridge, Massachusetts.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Sun+Y%22">Sun Y</searchLink>; Division of Infectious Diseases, Department of Medicine, Mass General Brigham Hospital, Boston, Massachusetts.; Center for Integrated Solutions for Infectious Diseases, Broad Institute, Cambridge, Massachusetts.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Liao+Y%22">Liao Y</searchLink>; Division of Infectious Diseases, Department of Medicine, Mass General Brigham Hospital, Boston, Massachusetts.; Center for Integrated Solutions for Infectious Diseases, Broad Institute, Cambridge, Massachusetts.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Zhong+L%22">Zhong L</searchLink>; Division of Infectious Diseases, Department of Medicine, Mass General Brigham Hospital, Boston, Massachusetts.; Center for Integrated Solutions for Infectious Diseases, Broad Institute, Cambridge, Massachusetts.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Burton+EM%22">Burton EM</searchLink>; Division of Infectious Diseases, Department of Medicine, Mass General Brigham Hospital, Boston, Massachusetts.; Center for Integrated Solutions for Infectious Diseases, Broad Institute, Cambridge, Massachusetts.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Mitra+B%22">Mitra B</searchLink>; Division of Infectious Diseases, Department of Medicine, Mass General Brigham Hospital, Boston, Massachusetts.; Center for Integrated Solutions for Infectious Diseases, Broad Institute, Cambridge, Massachusetts.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Gewurz+BE%22">Gewurz BE</searchLink>; Division of Infectious Diseases, Department of Medicine, Mass General Brigham Hospital, Boston, Massachusetts.; Center for Integrated Solutions for Infectious Diseases, Broad Institute, Cambridge, Massachusetts.; Department of Microbiology, Harvard Medical School, Boston, Massachusetts.
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        Value: 10.64898/2026.03.19.712937
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              Text: 2026 Mar 20
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