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Identifying Plasma Proteins Associated with Risk of Solid Cancers: A 25-Year Prospective Analysis of 4,712 Circulating Proteins in the ARIC Study.

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Title: Identifying Plasma Proteins Associated with Risk of Solid Cancers: A 25-Year Prospective Analysis of 4,712 Circulating Proteins in the ARIC Study.
Authors: Wang Z; Department of Genome Sciences, University of Virginia, Charlottesville, Virginia, United States of America.; UVA Comprehensive Cancer Center, Charlottesville, Virginia, United States of America., Burk VA; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America., Huang Z; Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom., Zahed H; International Agency for Research on Cancer, Lyon, France., Muller DC; Cancer Epidemiology and Prevention Research Unit, School of Public Health, Imperial College London, London, United Kingdom., Yarmolinsky J; Cancer Epidemiology and Prevention Research Unit, School of Public Health, Imperial College London, London, United Kingdom., Lee MA; International Agency for Research on Cancer, Lyon, France., Joshu CE; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America., Lin ZC; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America., Prizment A; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA., Butler KR; University of Mississippi Medical Center, Jackson, Mississippi., Couper DJ; Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States., Smith-Byrne K; Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom., Kolijn PM; Division of Environmental Epidemiology and Veterinary Public Health, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.; Julius Global Health, the Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, The Netherlands.; Department of Immunology, Erasmus MC, Rotterdam, the Netherlands., Vermeulen RCH; Division of Environmental Epidemiology and Veterinary Public Health, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.; Julius Global Health, the Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, The Netherlands., Riboli E; Cancer Epidemiology and Prevention Research Unit, School of Public Health, Imperial College London, London, United Kingdom., Gunter MJ; International Agency for Research on Cancer, Lyon, France.; Cancer Epidemiology and Prevention Research Unit, School of Public Health, Imperial College London, London, United Kingdom., Coresh J; Department of Population Health, New York University Grossman School of Medicine, New York, NY, United States.; Department of Medicine, New York University Grossman School of Medicine, New York, NY, United States., Chatterjee N; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.; Department of Oncology, Johns Hopkins University School of Medicine, and the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America., Platz EA; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.; Department of Oncology, Johns Hopkins University School of Medicine, and the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America.
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2026 Mar 18. Date of Electronic Publication: 2026 Mar 18.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Department of Genome Sciences, University of Virginia, Charlottesville, Virginia, United States of America.; UVA Comprehensive Cancer Center, Charlottesville, Virginia, United States of America.<br /><searchLink fieldCode="AU" term="%22Burk+VA%22">Burk VA</searchLink>; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Huang+Z%22">Huang Z</searchLink>; Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Zahed+H%22">Zahed H</searchLink>; International Agency for Research on Cancer, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Muller+DC%22">Muller DC</searchLink>; Cancer Epidemiology and Prevention Research Unit, School of Public Health, Imperial College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Yarmolinsky+J%22">Yarmolinsky J</searchLink>; Cancer Epidemiology and Prevention Research Unit, School of Public Health, Imperial College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Lee+MA%22">Lee MA</searchLink>; International Agency for Research on Cancer, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Joshu+CE%22">Joshu CE</searchLink>; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Lin+ZC%22">Lin ZC</searchLink>; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Prizment+A%22">Prizment A</searchLink>; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Butler+KR%22">Butler KR</searchLink>; University of Mississippi Medical Center, Jackson, Mississippi.<br /><searchLink fieldCode="AU" term="%22Couper+DJ%22">Couper DJ</searchLink>; Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.<br /><searchLink fieldCode="AU" term="%22Smith-Byrne+K%22">Smith-Byrne K</searchLink>; Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kolijn+PM%22">Kolijn PM</searchLink>; Division of Environmental Epidemiology and Veterinary Public Health, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.; Julius Global Health, the Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, The Netherlands.; Department of Immunology, Erasmus MC, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Vermeulen+RCH%22">Vermeulen RCH</searchLink>; Division of Environmental Epidemiology and Veterinary Public Health, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.; Julius Global Health, the Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Riboli+E%22">Riboli E</searchLink>; Cancer Epidemiology and Prevention Research Unit, School of Public Health, Imperial College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gunter+MJ%22">Gunter MJ</searchLink>; International Agency for Research on Cancer, Lyon, France.; Cancer Epidemiology and Prevention Research Unit, School of Public Health, Imperial College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Coresh+J%22">Coresh J</searchLink>; Department of Population Health, New York University Grossman School of Medicine, New York, NY, United States.; Department of Medicine, New York University Grossman School of Medicine, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Chatterjee+N%22">Chatterjee N</searchLink>; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.; Department of Oncology, Johns Hopkins University School of Medicine, and the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Platz+EA%22">Platz EA</searchLink>; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.; Department of Oncology, Johns Hopkins University School of Medicine, and the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America.
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