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Deciphering the Role of Cancer Stem Cells in Breast Cancer Brain Colonization Using a Novel Patient-Derived Model.

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Title: Deciphering the Role of Cancer Stem Cells in Breast Cancer Brain Colonization Using a Novel Patient-Derived Model.
Authors: Faletti S; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy., Richichi C; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy., Osti D; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy., Ceccacci E; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy., Bertalot G; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy.; Centre for Medical Sciences - CISMed, University of Trento, Trento, Italy.; Department of Anatomy and Pathological Histology, APSS, Santa Chiara Hospital, Trento, Italy., Cerutti C; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy., Giardina G; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy., Marinaro A; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy., Costanza B; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy., Gambino V; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy., Zaccheroni E; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy., Tosoni D; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy.; Department of Oncology and Haemato-Oncology, University of Milan, Milan, Italy., Filippone MG; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy., Del Corvo M; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy., Zhan Y; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy., Gravina T; Department of Translational Medicine, Center for Translational Research on Autoimmune and Allergic Disease (CAAD), University of Piemonte Orientale, Novara, Italy., Corà D; Department of Translational Medicine, Center for Translational Research on Autoimmune and Allergic Disease (CAAD), University of Piemonte Orientale, Novara, Italy., Patanè M; Neuropathology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Pollo B; Neuropathology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Giovanna Jodice M; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy.; Department of Oncology and Haemato-Oncology, University of Milan, Milan, Italy., Pece S; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy.; Department of Oncology and Haemato-Oncology, University of Milan, Milan, Italy., Weksler BB; Department of Medicine, Weill Medical College of Cornell University, New York, United States., Romero IA; Department of Biological Sciences, The Open University, Milton Keynes, United Kingdom., Couraud PO; Institut Cochin, Centre National de la Recherche Scientifique UMR 8104, Institut National de la Santé et de la Recherche Médicale (INSERM) U567, Université René Descartes, Paris, France., Munzone E; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy., Del Bene M; Department of Neurosurgery, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.; Department of Pharmacological and Biomolecular Sciences, Università Degli Studi Di Milano, Milan, Italy., DiMeco F; Department of Oncology and Haemato-Oncology, University of Milan, Milan, Italy.; Department of Neurosurgery, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy., Pelicci G; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy.; Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy.
Source: Advanced healthcare materials [Adv Healthc Mater] 2026 May; Vol. 15 (19), pp. e05789. Date of Electronic Publication: 2026 Mar 27.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101581613 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2192-2659 (Electronic) Linking ISSN: 21922640 NLM ISO Abbreviation: Adv Healthc Mater Subsets: MEDLINE
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  Data: Deciphering the Role of Cancer Stem Cells in Breast Cancer Brain Colonization Using a Novel Patient-Derived Model.
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  Data: <searchLink fieldCode="AU" term="%22Faletti+S%22">Faletti S</searchLink>; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Richichi+C%22">Richichi C</searchLink>; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Osti+D%22">Osti D</searchLink>; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ceccacci+E%22">Ceccacci E</searchLink>; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bertalot+G%22">Bertalot G</searchLink>; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy.; Centre for Medical Sciences - CISMed, University of Trento, Trento, Italy.; Department of Anatomy and Pathological Histology, APSS, Santa Chiara Hospital, Trento, Italy.<br /><searchLink fieldCode="AU" term="%22Cerutti+C%22">Cerutti C</searchLink>; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Giardina+G%22">Giardina G</searchLink>; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Marinaro+A%22">Marinaro A</searchLink>; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Costanza+B%22">Costanza B</searchLink>; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Gambino+V%22">Gambino V</searchLink>; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Zaccheroni+E%22">Zaccheroni E</searchLink>; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Tosoni+D%22">Tosoni D</searchLink>; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy.; Department of Oncology and Haemato-Oncology, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Filippone+MG%22">Filippone MG</searchLink>; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Del+Corvo+M%22">Del Corvo M</searchLink>; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Zhan+Y%22">Zhan Y</searchLink>; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Gravina+T%22">Gravina T</searchLink>; Department of Translational Medicine, Center for Translational Research on Autoimmune and Allergic Disease (CAAD), University of Piemonte Orientale, Novara, Italy.<br /><searchLink fieldCode="AU" term="%22Corà+D%22">Corà D</searchLink>; Department of Translational Medicine, Center for Translational Research on Autoimmune and Allergic Disease (CAAD), University of Piemonte Orientale, Novara, Italy.<br /><searchLink fieldCode="AU" term="%22Patanè+M%22">Patanè M</searchLink>; Neuropathology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Pollo+B%22">Pollo B</searchLink>; Neuropathology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Giovanna+Jodice+M%22">Giovanna Jodice M</searchLink>; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy.; Department of Oncology and Haemato-Oncology, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Pece+S%22">Pece S</searchLink>; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy.; Department of Oncology and Haemato-Oncology, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Weksler+BB%22">Weksler BB</searchLink>; Department of Medicine, Weill Medical College of Cornell University, New York, United States.<br /><searchLink fieldCode="AU" term="%22Romero+IA%22">Romero IA</searchLink>; Department of Biological Sciences, The Open University, Milton Keynes, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Couraud+PO%22">Couraud PO</searchLink>; Institut Cochin, Centre National de la Recherche Scientifique UMR 8104, Institut National de la Santé et de la Recherche Médicale (INSERM) U567, Université René Descartes, Paris, France.<br /><searchLink fieldCode="AU" term="%22Munzone+E%22">Munzone E</searchLink>; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Del+Bene+M%22">Del Bene M</searchLink>; Department of Neurosurgery, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.; Department of Pharmacological and Biomolecular Sciences, Università Degli Studi Di Milano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22DiMeco+F%22">DiMeco F</searchLink>; Department of Oncology and Haemato-Oncology, University of Milan, Milan, Italy.; Department of Neurosurgery, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Pelicci+G%22">Pelicci G</searchLink>; Department of Experimental Oncology, IRCCS, European Institute of Oncology (IEO), Milan, Italy.; Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy.
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  Data: <searchLink fieldCode="JN" term="%22101581613%22">Advanced healthcare materials</searchLink> [Adv Healthc Mater] 2026 May; Vol. 15 (19), pp. e05789. <i>Date of Electronic Publication: </i>2026 Mar 27.
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