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Efficacy and safety of intraoperative hyperthermic intraperitoneal chemotherapy for locally advanced colorectal cancer (HIPECT4): final analysis of randomized clinical trial.

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Title: Efficacy and safety of intraoperative hyperthermic intraperitoneal chemotherapy for locally advanced colorectal cancer (HIPECT4): final analysis of randomized clinical trial.
Authors: Arjona-Sánchez A; Unit of Oncologic and Pancreatic Surgery, University Hospital Reina Sofía, Córdoba, Spain.; Maimónides Biomedical Research Institute of Córdoba (IMIBIC)/Reina Sofia University Hospital/University of Córdoba, Cordoba, Spain., Gutiérrez-Calvo A; Unit of Peritoneal Oncologic Surgery, Surgery Department, Hospital Príncipe de Asturias, Alcalá de Henares, Madrid, Spain., Segura-Sampedro JJ; General & Digestive Surgery Service, Hospital Universitario Son Espases, Palma de Mallorca, Spain.; School of Medicine, Universidad CEU San Pablo, 28003 Madrid, Spain.; General & Digestive Surgery Service, Hospital Universitario La Paz, Madrid, Spain., Morales R; Unit of Oncologic and Pancreatic Surgery, Hospital Son Spaces, Palma de Mallorca, Spain., Pérez-Viejo E; Unit of Oncologic Surgery, Hospital University Fuenlabrada, Madrid, Spain., Concepción-Martín V; Unit of Peritoneal Oncologic Surgery and Colorectal Surgery, Hospital University Nuestra Señora de la Candelaria, Tenerife, Spain., Sánchez-García S; Unit of Surgery, Hospital University Ciudad Real, Ciudad Real, Spain., García-Fadrique A; Department of Surgery, Instituto Valenciano de Oncología, Valencia, Spain., Prieto-Nieto I; Unit of Oncologic Surgery, University Hospital La Paz, Madrid, Spain., Bijelic L; Unit of Surgery, Consorci Sanitari Integral, Hospital de Sant Joan Despí Moises Broggi, Barcelona, Spain., Torres-Melero J; Unit of Surgery, Hospital de Torrecárdenas, Almería, Spain., Ramirez-Faraco M; Unit of Oncologic Surgery, University General Hospital Reina Sofia, Murcia, Spain., Prada-Villaverde A; Unit of Surgery, Hospital University Infanta Cristina, Badajoz, Spain., Carrasco-Campos J; Unit of Surgery, Hospital Regional University of Malaga, Malaga, Spain., Artiles-Armas M; Department of General and Digestive Surgery, University Hospital Gran Canaria Dr. Negrín, Las Palmas de Gran Canaria, Canary Islands, Spain., Villarejo-Campos P; Unit of Oncologic Surgery, Hospital Fundación Jimenez Diaz, Madrid, Spain., Ortega-Pérez G; Unit of Surgery, MD Anderson Cancer Center, Madrid, Spain., Boldo-Roda E; Unit of Surgery, Hospital Provincial Castellón, Castellón, Spain., Sánchez-Hidalgo JM; Unit of Oncologic and Pancreatic Surgery, University Hospital Reina Sofía, Córdoba, Spain.; Maimónides Biomedical Research Institute of Córdoba (IMIBIC)/Reina Sofia University Hospital/University of Córdoba, Cordoba, Spain., Casado-Adam A; Unit of Oncologic and Pancreatic Surgery, University Hospital Reina Sofía, Córdoba, Spain.; Maimónides Biomedical Research Institute of Córdoba (IMIBIC)/Reina Sofia University Hospital/University of Córdoba, Cordoba, Spain., Rodríguez-Ortiz L; Unit of Oncologic and Pancreatic Surgery, University Hospital Reina Sofía, Córdoba, Spain.; Maimónides Biomedical Research Institute of Córdoba (IMIBIC)/Reina Sofia University Hospital/University of Córdoba, Cordoba, Spain., Rufian-Andújar B; Unit of Oncologic and Pancreatic Surgery, University Hospital Reina Sofía, Córdoba, Spain.; Maimónides Biomedical Research Institute of Córdoba (IMIBIC)/Reina Sofia University Hospital/University of Córdoba, Cordoba, Spain., Aranda E; Maimónides Biomedical Research Institute of Córdoba (IMIBIC)/Reina Sofia University Hospital/University of Córdoba, Cordoba, Spain.; Unit of Medical Oncology, University Hospital Reina Sofia, Córdoba, Spain., Cano-Osuna MT; Maimónides Biomedical Research Institute of Córdoba (IMIBIC)/Reina Sofia University Hospital/University of Córdoba, Cordoba, Spain.; Unit of Medical Oncology, University Hospital Reina Sofia, Córdoba, Spain., Díaz-López C; Unit of Oncologic and Pancreatic Surgery, University Hospital Reina Sofía, Córdoba, Spain., Romero-Ruiz A; Maimónides Biomedical Research Institute of Córdoba (IMIBIC)/Reina Sofia University Hospital/University of Córdoba, Cordoba, Spain., Vazquez-Borrego MC; Maimónides Biomedical Research Institute of Córdoba (IMIBIC)/Reina Sofia University Hospital/University of Córdoba, Cordoba, Spain., Rufián-Peña S; Unit of Oncologic and Pancreatic Surgery, University Hospital Reina Sofía, Córdoba, Spain.
Source: BJS open [BJS Open] 2025 Mar 05; Vol. 10 (2).
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101722685 Publication Model: Print Cited Medium: Internet ISSN: 2474-9842 (Electronic) Linking ISSN: 24749842 NLM ISO Abbreviation: BJS Open Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Efficacy and safety of intraoperative hyperthermic intraperitoneal chemotherapy for locally advanced colorectal cancer (HIPECT4): final analysis of randomized clinical trial.
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  Data: <searchLink fieldCode="AU" term="%22Arjona-Sánchez+A%22">Arjona-Sánchez A</searchLink>; Unit of Oncologic and Pancreatic Surgery, University Hospital Reina Sofía, Córdoba, Spain.; Maimónides Biomedical Research Institute of Córdoba (IMIBIC)/Reina Sofia University Hospital/University of Córdoba, Cordoba, Spain.<br /><searchLink fieldCode="AU" term="%22Gutiérrez-Calvo+A%22">Gutiérrez-Calvo A</searchLink>; Unit of Peritoneal Oncologic Surgery, Surgery Department, Hospital Príncipe de Asturias, Alcalá de Henares, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Segura-Sampedro+JJ%22">Segura-Sampedro JJ</searchLink>; General & Digestive Surgery Service, Hospital Universitario Son Espases, Palma de Mallorca, Spain.; School of Medicine, Universidad CEU San Pablo, 28003 Madrid, Spain.; General & Digestive Surgery Service, Hospital Universitario La Paz, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Morales+R%22">Morales R</searchLink>; Unit of Oncologic and Pancreatic Surgery, Hospital Son Spaces, Palma de Mallorca, Spain.<br /><searchLink fieldCode="AU" term="%22Pérez-Viejo+E%22">Pérez-Viejo E</searchLink>; Unit of Oncologic Surgery, Hospital University Fuenlabrada, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Concepción-Martín+V%22">Concepción-Martín V</searchLink>; Unit of Peritoneal Oncologic Surgery and Colorectal Surgery, Hospital University Nuestra Señora de la Candelaria, Tenerife, Spain.<br /><searchLink fieldCode="AU" term="%22Sánchez-García+S%22">Sánchez-García S</searchLink>; Unit of Surgery, Hospital University Ciudad Real, Ciudad Real, Spain.<br /><searchLink fieldCode="AU" term="%22García-Fadrique+A%22">García-Fadrique A</searchLink>; Department of Surgery, Instituto Valenciano de Oncología, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Prieto-Nieto+I%22">Prieto-Nieto I</searchLink>; Unit of Oncologic Surgery, University Hospital La Paz, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Bijelic+L%22">Bijelic L</searchLink>; Unit of Surgery, Consorci Sanitari Integral, Hospital de Sant Joan Despí Moises Broggi, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Torres-Melero+J%22">Torres-Melero J</searchLink>; Unit of Surgery, Hospital de Torrecárdenas, Almería, Spain.<br /><searchLink fieldCode="AU" term="%22Ramirez-Faraco+M%22">Ramirez-Faraco M</searchLink>; Unit of Oncologic Surgery, University General Hospital Reina Sofia, Murcia, Spain.<br /><searchLink fieldCode="AU" term="%22Prada-Villaverde+A%22">Prada-Villaverde A</searchLink>; Unit of Surgery, Hospital University Infanta Cristina, Badajoz, Spain.<br /><searchLink fieldCode="AU" term="%22Carrasco-Campos+J%22">Carrasco-Campos J</searchLink>; Unit of Surgery, Hospital Regional University of Malaga, Malaga, Spain.<br /><searchLink fieldCode="AU" term="%22Artiles-Armas+M%22">Artiles-Armas M</searchLink>; Department of General and Digestive Surgery, University Hospital Gran Canaria Dr. Negrín, Las Palmas de Gran Canaria, Canary Islands, Spain.<br /><searchLink fieldCode="AU" term="%22Villarejo-Campos+P%22">Villarejo-Campos P</searchLink>; Unit of Oncologic Surgery, Hospital Fundación Jimenez Diaz, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Ortega-Pérez+G%22">Ortega-Pérez G</searchLink>; Unit of Surgery, MD Anderson Cancer Center, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Boldo-Roda+E%22">Boldo-Roda E</searchLink>; Unit of Surgery, Hospital Provincial Castellón, Castellón, Spain.<br /><searchLink fieldCode="AU" term="%22Sánchez-Hidalgo+JM%22">Sánchez-Hidalgo JM</searchLink>; Unit of Oncologic and Pancreatic Surgery, University Hospital Reina Sofía, Córdoba, Spain.; Maimónides Biomedical Research Institute of Córdoba (IMIBIC)/Reina Sofia University Hospital/University of Córdoba, Cordoba, Spain.<br /><searchLink fieldCode="AU" term="%22Casado-Adam+A%22">Casado-Adam A</searchLink>; Unit of Oncologic and Pancreatic Surgery, University Hospital Reina Sofía, Córdoba, Spain.; Maimónides Biomedical Research Institute of Córdoba (IMIBIC)/Reina Sofia University Hospital/University of Córdoba, Cordoba, Spain.<br /><searchLink fieldCode="AU" term="%22Rodríguez-Ortiz+L%22">Rodríguez-Ortiz L</searchLink>; Unit of Oncologic and Pancreatic Surgery, University Hospital Reina Sofía, Córdoba, Spain.; Maimónides Biomedical Research Institute of Córdoba (IMIBIC)/Reina Sofia University Hospital/University of Córdoba, Cordoba, Spain.<br /><searchLink fieldCode="AU" term="%22Rufian-Andújar+B%22">Rufian-Andújar B</searchLink>; Unit of Oncologic and Pancreatic Surgery, University Hospital Reina Sofía, Córdoba, Spain.; Maimónides Biomedical Research Institute of Córdoba (IMIBIC)/Reina Sofia University Hospital/University of Córdoba, Cordoba, Spain.<br /><searchLink fieldCode="AU" term="%22Aranda+E%22">Aranda E</searchLink>; Maimónides Biomedical Research Institute of Córdoba (IMIBIC)/Reina Sofia University Hospital/University of Córdoba, Cordoba, Spain.; Unit of Medical Oncology, University Hospital Reina Sofia, Córdoba, Spain.<br /><searchLink fieldCode="AU" term="%22Cano-Osuna+MT%22">Cano-Osuna MT</searchLink>; Maimónides Biomedical Research Institute of Córdoba (IMIBIC)/Reina Sofia University Hospital/University of Córdoba, Cordoba, Spain.; Unit of Medical Oncology, University Hospital Reina Sofia, Córdoba, Spain.<br /><searchLink fieldCode="AU" term="%22Díaz-López+C%22">Díaz-López C</searchLink>; Unit of Oncologic and Pancreatic Surgery, University Hospital Reina Sofía, Córdoba, Spain.<br /><searchLink fieldCode="AU" term="%22Romero-Ruiz+A%22">Romero-Ruiz A</searchLink>; Maimónides Biomedical Research Institute of Córdoba (IMIBIC)/Reina Sofia University Hospital/University of Córdoba, Cordoba, Spain.<br /><searchLink fieldCode="AU" term="%22Vazquez-Borrego+MC%22">Vazquez-Borrego MC</searchLink>; Maimónides Biomedical Research Institute of Córdoba (IMIBIC)/Reina Sofia University Hospital/University of Córdoba, Cordoba, Spain.<br /><searchLink fieldCode="AU" term="%22Rufián-Peña+S%22">Rufián-Peña S</searchLink>; Unit of Oncologic and Pancreatic Surgery, University Hospital Reina Sofía, Córdoba, Spain.
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