3D Vessels-on-Chip using isogenic hiPSC-derived VSMCs reveal NOTCH3-driven alterations in brain small vessel disease.
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| Title: | 3D Vessels-on-Chip using isogenic hiPSC-derived VSMCs reveal NOTCH3-driven alterations in brain small vessel disease. |
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| Authors: | Vila Cuenca M; Department of Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands; Department of Anatomy & Embryology, Leiden University Medical Center, Leiden, the Netherlands., Tsikari T; Department of Anatomy & Embryology, Leiden University Medical Center, Leiden, the Netherlands., Cerfontaine MN; Department of Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands., Gallant JL; Department of Anatomy & Embryology, Leiden University Medical Center, Leiden, the Netherlands., van den Hil FE; Department of Anatomy & Embryology, Leiden University Medical Center, Leiden, the Netherlands., Bouma MJ; Leiden University Medical Center hiPSC Center, Leiden, the Netherlands., Dijkstra KL; Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands., Gravesteijn G; Department of Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands., de Vries AAF; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands., Mummery CL; Department of Anatomy & Embryology, Leiden University Medical Center, Leiden, the Netherlands., Rutten JW; Department of Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands. Electronic address: j.w.rutten@lumc.nl., Lesnik Oberstein SAJ; Department of Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands. Electronic address: s.a.m.j.lesnik@lumc.nl., Orlova VV; Department of Anatomy & Embryology, Leiden University Medical Center, Leiden, the Netherlands. Electronic address: v.orlova@lumc.nl. |
| Source: | Stem cell reports [Stem Cell Reports] 2026 Apr 14; Vol. 21 (4), pp. 102863. Date of Electronic Publication: 2026 Mar 26. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 101611300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-6711 (Electronic) Linking ISSN: 22136711 NLM ISO Abbreviation: Stem Cell Reports Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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