Beyond local injury: pathogenic roles of metabolic, endocrine, and aging-associated systemic factors in tendinopathy and novel therapeutic strategies.

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Title: Beyond local injury: pathogenic roles of metabolic, endocrine, and aging-associated systemic factors in tendinopathy and novel therapeutic strategies.
Authors: Lin Y; Department of Oral Implantology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Kaixuan Road 268, Hangzhou, Zhejiang Province, China., Liu Z; Department of Oral Implantology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Kaixuan Road 268, Hangzhou, Zhejiang Province, China., Peng L; Department of Oral Implantology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Kaixuan Road 268, Hangzhou, Zhejiang Province, China., Wang S; Department of Oral Implantology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Kaixuan Road 268, Hangzhou, Zhejiang Province, China., Li K; Department of Oral Implantology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Kaixuan Road 268, Hangzhou, Zhejiang Province, China., Lv X; Department of Thoracic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China., He J; Department of Oral Implantology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Kaixuan Road 268, Hangzhou, Zhejiang Province, China. hejianxiang@zju.edu.cn.
Source: Journal of orthopaedic surgery and research [J Orthop Surg Res] 2026 Mar 27; Vol. 21 (1). Date of Electronic Publication: 2026 Mar 27.
Publication Type: Journal Article; Review
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101265112 Publication Model: Electronic Cited Medium: Internet ISSN: 1749-799X (Electronic) Linking ISSN: 1749799X NLM ISO Abbreviation: J Orthop Surg Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Beyond local injury: pathogenic roles of metabolic, endocrine, and aging-associated systemic factors in tendinopathy and novel therapeutic strategies.
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  Data: <searchLink fieldCode="AU" term="%22Lin+Y%22">Lin Y</searchLink>; Department of Oral Implantology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Kaixuan Road 268, Hangzhou, Zhejiang Province, China.<br /><searchLink fieldCode="AU" term="%22Liu+Z%22">Liu Z</searchLink>; Department of Oral Implantology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Kaixuan Road 268, Hangzhou, Zhejiang Province, China.<br /><searchLink fieldCode="AU" term="%22Peng+L%22">Peng L</searchLink>; Department of Oral Implantology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Kaixuan Road 268, Hangzhou, Zhejiang Province, China.<br /><searchLink fieldCode="AU" term="%22Wang+S%22">Wang S</searchLink>; Department of Oral Implantology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Kaixuan Road 268, Hangzhou, Zhejiang Province, China.<br /><searchLink fieldCode="AU" term="%22Li+K%22">Li K</searchLink>; Department of Oral Implantology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Kaixuan Road 268, Hangzhou, Zhejiang Province, China.<br /><searchLink fieldCode="AU" term="%22Lv+X%22">Lv X</searchLink>; Department of Thoracic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22He+J%22">He J</searchLink>; Department of Oral Implantology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Kaixuan Road 268, Hangzhou, Zhejiang Province, China. hejianxiang@zju.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101265112%22">Journal of orthopaedic surgery and research</searchLink> [J Orthop Surg Res] 2026 Mar 27; Vol. 21 (1). <i>Date of Electronic Publication: </i>2026 Mar 27.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101265112 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1749-799X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221749799X%22">1749799X </searchLink><i>NLM ISO Abbreviation: </i>J Orthop Surg Res <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41896960
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        Value: 10.1186/s13018-026-06820-5
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        Text: English
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      – TitleFull: Beyond local injury: pathogenic roles of metabolic, endocrine, and aging-associated systemic factors in tendinopathy and novel therapeutic strategies.
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            – D: 27
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              Text: 2026 Mar 27
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              Y: 2026
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