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Chorioallantoic membrane (CAM) of chicken embryo as an assay for biomaterial and drug testing: Current gaps and future directions.

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Title: Chorioallantoic membrane (CAM) of chicken embryo as an assay for biomaterial and drug testing: Current gaps and future directions.
Authors: Petikova Z; Department of Biology and Physiology, University of Veterinary Medicine and Pharmacy in Košice, Komenského 73, 041 81, Košice, Slovak Republic; Terasaki Institute for Biomedical Innovation (TIBI), 11507 W Olympic Blvd, Los Angeles, CA, USA. Electronic address: zuzana.petikova@uvlf.sk., Demcisakova Z; Department of Morphological Disciplines, University of Veterinary Medicine and Pharmacy in Košice, Komenského 73, 041 81, Košice, Slovak Republic., Petrovova E; Department of Morphological Disciplines, University of Veterinary Medicine and Pharmacy in Košice, Komenského 73, 041 81, Košice, Slovak Republic., Luptakova L; Department of Biology and Physiology, University of Veterinary Medicine and Pharmacy in Košice, Komenského 73, 041 81, Košice, Slovak Republic., de Sousa Abreu AP; São Paulo State University (UNESP), Bioengineering & Biomaterials Group, School of Pharmaceutical Sciences, Zip Code: 14800-903, Araraquara, SP, Brazil., Burd BS; São Paulo State University (UNESP), Bioengineering & Biomaterials Group, School of Pharmaceutical Sciences, Zip Code: 14800-903, Araraquara, SP, Brazil., Guerra NB; São Paulo State University (UNESP), School of Sciences, Zip Code: 17033-360, Bauru, SP, Brazil., Carvalho BG; Terasaki Institute for Biomedical Innovation (TIBI), 11507 W Olympic Blvd, Los Angeles, CA, USA; University of Campinas (UNICAMP), Department of Materials and Bioprocesses Engineering, School of Chemical Engineering, Zip Code: 13083-852, Campinas, SP, Brazil., Peirsman A; Terasaki Institute for Biomedical Innovation (TIBI), 11507 W Olympic Blvd, Los Angeles, CA, USA; Plastic, Reconstructive and Aesthetic Surgery, University Hospital Ghent, Ghent, Belgium., Nguyen HT; Terasaki Institute for Biomedical Innovation (TIBI), 11507 W Olympic Blvd, Los Angeles, CA, USA., Dos Santos LS; Institute of Exact and Technological Sciences, Federal University of Viçosa (UFV), Rio Paranaíba, MG, 38810-000, Brazil; University of São Paulo (USP), Faculty of Philosophy, Sciences, and Languages of Ribeirão Preto, 3900 Bandeirantes Avenue, Ribeirão Preto, SP, 14040-901, Brazil., Chagas PAM; Federal University of São Carlos, Department of Chemical Engineering, Rodovia Washington Luís, km 235, 13560-970, São Carlos, SP, Brazil., Mussagy CU; Escuela de Agronomía, Facultad de Ciencias Agronómicas y de los Alimentos, Pontificia Universidad Católica de Valparaíso, Chile., de Mendonça RJ; Department of Biochemistry, Pharmacology and Physiology, Federal University of Triangulo Mineiro (UFTM), Uberaba, Minas Gerais, Brazil., Herculano RD; Terasaki Institute for Biomedical Innovation (TIBI), 11507 W Olympic Blvd, Los Angeles, CA, USA; São Paulo State University (UNESP), Bioengineering & Biomaterials Group, School of Pharmaceutical Sciences, Zip Code: 14800-903, Araraquara, SP, Brazil; Autonomy Research Center for STEAHM (ARCS), California State University, Northridge, CA, 91324, USA. Electronic address: rondinelli.herculano@unesp.br., Floriano JF; São Paulo State University (UNESP), Bioengineering & Biomaterials Group, School of Pharmaceutical Sciences, Zip Code: 14800-903, Araraquara, SP, Brazil; São Paulo State University (UNESP), School of Sciences, Zip Code: 17033-360, Bauru, SP, Brazil. Electronic address: juliana.floriano@unesp.br.
Source: Biomaterials advances [Biomater Adv] 2026 Jul; Vol. 184, pp. 214827. Date of Electronic Publication: 2026 Mar 23.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 9918383886206676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2772-9508 (Electronic) Linking ISSN: 27729508 NLM ISO Abbreviation: Biomater Adv Subsets: MEDLINE
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  Data: Chorioallantoic membrane (CAM) of chicken embryo as an assay for biomaterial and drug testing: Current gaps and future directions.
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  Data: <searchLink fieldCode="AU" term="%22Petikova+Z%22">Petikova Z</searchLink>; Department of Biology and Physiology, University of Veterinary Medicine and Pharmacy in Košice, Komenského 73, 041 81, Košice, Slovak Republic; Terasaki Institute for Biomedical Innovation (TIBI), 11507 W Olympic Blvd, Los Angeles, CA, USA. Electronic address: zuzana.petikova@uvlf.sk.<br /><searchLink fieldCode="AU" term="%22Demcisakova+Z%22">Demcisakova Z</searchLink>; Department of Morphological Disciplines, University of Veterinary Medicine and Pharmacy in Košice, Komenského 73, 041 81, Košice, Slovak Republic.<br /><searchLink fieldCode="AU" term="%22Petrovova+E%22">Petrovova E</searchLink>; Department of Morphological Disciplines, University of Veterinary Medicine and Pharmacy in Košice, Komenského 73, 041 81, Košice, Slovak Republic.<br /><searchLink fieldCode="AU" term="%22Luptakova+L%22">Luptakova L</searchLink>; Department of Biology and Physiology, University of Veterinary Medicine and Pharmacy in Košice, Komenského 73, 041 81, Košice, Slovak Republic.<br /><searchLink fieldCode="AU" term="%22de+Sousa+Abreu+AP%22">de Sousa Abreu AP</searchLink>; São Paulo State University (UNESP), Bioengineering & Biomaterials Group, School of Pharmaceutical Sciences, Zip Code: 14800-903, Araraquara, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Burd+BS%22">Burd BS</searchLink>; São Paulo State University (UNESP), Bioengineering & Biomaterials Group, School of Pharmaceutical Sciences, Zip Code: 14800-903, Araraquara, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Guerra+NB%22">Guerra NB</searchLink>; São Paulo State University (UNESP), School of Sciences, Zip Code: 17033-360, Bauru, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Carvalho+BG%22">Carvalho BG</searchLink>; Terasaki Institute for Biomedical Innovation (TIBI), 11507 W Olympic Blvd, Los Angeles, CA, USA; University of Campinas (UNICAMP), Department of Materials and Bioprocesses Engineering, School of Chemical Engineering, Zip Code: 13083-852, Campinas, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Peirsman+A%22">Peirsman A</searchLink>; Terasaki Institute for Biomedical Innovation (TIBI), 11507 W Olympic Blvd, Los Angeles, CA, USA; Plastic, Reconstructive and Aesthetic Surgery, University Hospital Ghent, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Nguyen+HT%22">Nguyen HT</searchLink>; Terasaki Institute for Biomedical Innovation (TIBI), 11507 W Olympic Blvd, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Dos+Santos+LS%22">Dos Santos LS</searchLink>; Institute of Exact and Technological Sciences, Federal University of Viçosa (UFV), Rio Paranaíba, MG, 38810-000, Brazil; University of São Paulo (USP), Faculty of Philosophy, Sciences, and Languages of Ribeirão Preto, 3900 Bandeirantes Avenue, Ribeirão Preto, SP, 14040-901, Brazil.<br /><searchLink fieldCode="AU" term="%22Chagas+PAM%22">Chagas PAM</searchLink>; Federal University of São Carlos, Department of Chemical Engineering, Rodovia Washington Luís, km 235, 13560-970, São Carlos, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Mussagy+CU%22">Mussagy CU</searchLink>; Escuela de Agronomía, Facultad de Ciencias Agronómicas y de los Alimentos, Pontificia Universidad Católica de Valparaíso, Chile.<br /><searchLink fieldCode="AU" term="%22de+Mendonça+RJ%22">de Mendonça RJ</searchLink>; Department of Biochemistry, Pharmacology and Physiology, Federal University of Triangulo Mineiro (UFTM), Uberaba, Minas Gerais, Brazil.<br /><searchLink fieldCode="AU" term="%22Herculano+RD%22">Herculano RD</searchLink>; Terasaki Institute for Biomedical Innovation (TIBI), 11507 W Olympic Blvd, Los Angeles, CA, USA; São Paulo State University (UNESP), Bioengineering & Biomaterials Group, School of Pharmaceutical Sciences, Zip Code: 14800-903, Araraquara, SP, Brazil; Autonomy Research Center for STEAHM (ARCS), California State University, Northridge, CA, 91324, USA. Electronic address: rondinelli.herculano@unesp.br.<br /><searchLink fieldCode="AU" term="%22Floriano+JF%22">Floriano JF</searchLink>; São Paulo State University (UNESP), Bioengineering & Biomaterials Group, School of Pharmaceutical Sciences, Zip Code: 14800-903, Araraquara, SP, Brazil; São Paulo State University (UNESP), School of Sciences, Zip Code: 17033-360, Bauru, SP, Brazil. Electronic address: juliana.floriano@unesp.br.
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  Data: <searchLink fieldCode="JN" term="%229918383886206676%22">Biomaterials advances</searchLink> [Biomater Adv] 2026 Jul; Vol. 184, pp. 214827. <i>Date of Electronic Publication: </i>2026 Mar 23.
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