Green diastereoselective synthesis of spiropyrrolidines by the one-pot three component reaction of isatins, THβC and 5-arylidene-thiazolidine-2,4-diones and its anticancer evaluation.
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| Title: | Green diastereoselective synthesis of spiropyrrolidines by the one-pot three component reaction of isatins, THβC and 5-arylidene-thiazolidine-2,4-diones and its anticancer evaluation. |
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| Authors: | Mohan M; Department of Chemistry, University of Kerala, Kariavattom Campus, Thiruvananthapuram 695581, Kerala, India., Sudhina S; Translational Nanomedicine and Lifestyle Disease Research Laboratory, Department of Biochemistry, University of Kerala, Kariavattom campus, Thiruvananthapuram 695581, Kerala, India; Centre for Advanced Cancer Research, Department of Biochemistry, University of Kerala, Kariavattom Campus, Thiruvananthapuram 695581, Kerala, India., Meenakshy CB; Department of Chemistry, University of Kerala, Kariavattom Campus, Thiruvananthapuram 695581, Kerala, India., Ruksana CS; Department of Chemistry, St. Michael's College, Cherthala, Alappuzha 688539, Kerala, India., Jayasree EG; Department of Applied Chemistry, Cochin University of Science and Technology, Kochi 682022, Kerala, India., Janeesh PA; Translational Nanomedicine and Lifestyle Disease Research Laboratory, Department of Biochemistry, University of Kerala, Kariavattom campus, Thiruvananthapuram 695581, Kerala, India; Centre for Advanced Cancer Research, Department of Biochemistry, University of Kerala, Kariavattom Campus, Thiruvananthapuram 695581, Kerala, India.. Electronic address: janeeshbiochemistry@keralauniversity.ac.in., Deepthi A; Department of Chemistry, University of Kerala, Kariavattom Campus, Thiruvananthapuram 695581, Kerala, India. Electronic address: anideepthi@gmail.com. |
| Source: | Bioorganic chemistry [Bioorg Chem] 2026 Jul 05; Vol. 175, pp. 109786. Date of Electronic Publication: 2026 Mar 23. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41903476 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Green diastereoselective synthesis of spiropyrrolidines by the one-pot three component reaction of isatins, THβC and 5-arylidene-thiazolidine-2,4-diones and its anticancer evaluation. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Mohan+M%22">Mohan M</searchLink>; Department of Chemistry, University of Kerala, Kariavattom Campus, Thiruvananthapuram 695581, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Sudhina+S%22">Sudhina S</searchLink>; Translational Nanomedicine and Lifestyle Disease Research Laboratory, Department of Biochemistry, University of Kerala, Kariavattom campus, Thiruvananthapuram 695581, Kerala, India; Centre for Advanced Cancer Research, Department of Biochemistry, University of Kerala, Kariavattom Campus, Thiruvananthapuram 695581, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Meenakshy+CB%22">Meenakshy CB</searchLink>; Department of Chemistry, University of Kerala, Kariavattom Campus, Thiruvananthapuram 695581, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Ruksana+CS%22">Ruksana CS</searchLink>; Department of Chemistry, St. Michael's College, Cherthala, Alappuzha 688539, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Jayasree+EG%22">Jayasree EG</searchLink>; Department of Applied Chemistry, Cochin University of Science and Technology, Kochi 682022, Kerala, India.<br /><searchLink fieldCode="AU" term="%22Janeesh+PA%22">Janeesh PA</searchLink>; Translational Nanomedicine and Lifestyle Disease Research Laboratory, Department of Biochemistry, University of Kerala, Kariavattom campus, Thiruvananthapuram 695581, Kerala, India; Centre for Advanced Cancer Research, Department of Biochemistry, University of Kerala, Kariavattom Campus, Thiruvananthapuram 695581, Kerala, India.. Electronic address: janeeshbiochemistry@keralauniversity.ac.in.<br /><searchLink fieldCode="AU" term="%22Deepthi+A%22">Deepthi A</searchLink>; Department of Chemistry, University of Kerala, Kariavattom Campus, Thiruvananthapuram 695581, Kerala, India. Electronic address: anideepthi@gmail.com. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%221303703%22">Bioorganic chemistry</searchLink> [Bioorg Chem] 2026 Jul 05; Vol. 175, pp. 109786. <i>Date of Electronic Publication: </i>2026 Mar 23. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>1303703 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1090-2120 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200452068%22">00452068 </searchLink><i>NLM ISO Abbreviation: </i>Bioorg Chem <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41903476 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.bioorg.2026.109786 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 109786 Titles: – TitleFull: Green diastereoselective synthesis of spiropyrrolidines by the one-pot three component reaction of isatins, THβC and 5-arylidene-thiazolidine-2,4-diones and its anticancer evaluation. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Mohan M – PersonEntity: Name: NameFull: Sudhina S – PersonEntity: Name: NameFull: Meenakshy CB – PersonEntity: Name: NameFull: Ruksana CS – PersonEntity: Name: NameFull: Jayasree EG – PersonEntity: Name: NameFull: Janeesh PA – PersonEntity: Name: NameFull: Deepthi A IsPartOfRelationships: – BibEntity: Dates: – D: 05 M: 07 Text: 2026 Jul 05 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1090-2120 Numbering: – Type: volume Value: 175 Titles: – TitleFull: Bioorganic chemistry Type: main |
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