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Double-stranded sperm DNA fragmentation measured with neutral comet assay as a predictor of IVF outcomes: evidence from three European clinics in a multi-centred prospective study.

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Title: Double-stranded sperm DNA fragmentation measured with neutral comet assay as a predictor of IVF outcomes: evidence from three European clinics in a multi-centred prospective study.
Authors: Humaidan P; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Central Denmark Region, University Clinic for Fertility, Skive, Denmark., Povlsen BB; Central Denmark Region, University Clinic for Fertility, Skive, Denmark., Drakeley AJ; Hewitt Fertility Centre, Liverpool Women's NHS Foundation Trust, Liverpool, UK.; University of Liverpool, Liverpool, UK., Jensen MB; Central Denmark Region, University Clinic for Fertility, Skive, Denmark., Gabrielsen AV; The Fertility Clinic, Horsens Regional Hospital, Horsens, Denmark., McDowell SH; Future Medicines Institute, Centre for Digital Health Technology, Ulster University, Belfast, UK., Moore L; Department of Biology, University of York, York, UK., Ledgerwood CJ; Examen, Weavers Court Business Park, Belfast, UK., Rae L; Examen, Weavers Court Business Park, Belfast, UK., Sloan A; Examen, Weavers Court Business Park, Belfast, UK., Lawlor M; Examen, Weavers Court Business Park, Belfast, UK., Poots L; Examen, Weavers Court Business Park, Belfast, UK., Bailie E; Future Medicines Institute, Centre for Digital Health Technology, Ulster University, Belfast, UK., Lunt RL; Hewitt Fertility Centre, Liverpool Women's NHS Foundation Trust, Liverpool, UK., Newton E; Hewitt Fertility Centre, Liverpool Women's NHS Foundation Trust, Liverpool, UK., Gregoire RC; Hewitt Fertility Centre, Liverpool Women's NHS Foundation Trust, Liverpool, UK., Moore TCB; Future Medicines Institute, Centre for Digital Health Technology, Ulster University, Belfast, UK.; Examen, Weavers Court Business Park, Belfast, UK., Esteves SC; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; ANDROFERT, Andrology and Human Reproduction Clinic, Campinas, Brazil.; Division of Urology, Department of Surgery, University of Campinas (UNICAMP), Campinas, Brazil.
Source: Human reproduction (Oxford, England) [Hum Reprod] 2026 May 01; Vol. 41 (5), pp. 677-688.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 8701199 Publication Model: Print Cited Medium: Internet ISSN: 1460-2350 (Electronic) Linking ISSN: 02681161 NLM ISO Abbreviation: Hum Reprod Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Humaidan+P%22">Humaidan P</searchLink>; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; Central Denmark Region, University Clinic for Fertility, Skive, Denmark.<br /><searchLink fieldCode="AU" term="%22Povlsen+BB%22">Povlsen BB</searchLink>; Central Denmark Region, University Clinic for Fertility, Skive, Denmark.<br /><searchLink fieldCode="AU" term="%22Drakeley+AJ%22">Drakeley AJ</searchLink>; Hewitt Fertility Centre, Liverpool Women's NHS Foundation Trust, Liverpool, UK.; University of Liverpool, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Jensen+MB%22">Jensen MB</searchLink>; Central Denmark Region, University Clinic for Fertility, Skive, Denmark.<br /><searchLink fieldCode="AU" term="%22Gabrielsen+AV%22">Gabrielsen AV</searchLink>; The Fertility Clinic, Horsens Regional Hospital, Horsens, Denmark.<br /><searchLink fieldCode="AU" term="%22McDowell+SH%22">McDowell SH</searchLink>; Future Medicines Institute, Centre for Digital Health Technology, Ulster University, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Moore+L%22">Moore L</searchLink>; Department of Biology, University of York, York, UK.<br /><searchLink fieldCode="AU" term="%22Ledgerwood+CJ%22">Ledgerwood CJ</searchLink>; Examen, Weavers Court Business Park, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Rae+L%22">Rae L</searchLink>; Examen, Weavers Court Business Park, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Sloan+A%22">Sloan A</searchLink>; Examen, Weavers Court Business Park, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Lawlor+M%22">Lawlor M</searchLink>; Examen, Weavers Court Business Park, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Poots+L%22">Poots L</searchLink>; Examen, Weavers Court Business Park, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Bailie+E%22">Bailie E</searchLink>; Future Medicines Institute, Centre for Digital Health Technology, Ulster University, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Lunt+RL%22">Lunt RL</searchLink>; Hewitt Fertility Centre, Liverpool Women's NHS Foundation Trust, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Newton+E%22">Newton E</searchLink>; Hewitt Fertility Centre, Liverpool Women's NHS Foundation Trust, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Gregoire+RC%22">Gregoire RC</searchLink>; Hewitt Fertility Centre, Liverpool Women's NHS Foundation Trust, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Moore+TCB%22">Moore TCB</searchLink>; Future Medicines Institute, Centre for Digital Health Technology, Ulster University, Belfast, UK.; Examen, Weavers Court Business Park, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Esteves+SC%22">Esteves SC</searchLink>; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.; ANDROFERT, Andrology and Human Reproduction Clinic, Campinas, Brazil.; Division of Urology, Department of Surgery, University of Campinas (UNICAMP), Campinas, Brazil.
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