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Advancing precision health discovery in a genetically diverse health system.

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Title: Advancing precision health discovery in a genetically diverse health system.
Authors: Haas R; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Urology, University of California, Los Angeles, Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address: rhaas@mednet.ucla.edu., Margolis MP; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Neurology, University of California, Los Angeles, Los Angeles, CA 90095, USA., Wei A; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Interdepartmental Bioinformatics Program, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Computational Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA., Yamaguchi TN; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Urology, University of California, Los Angeles, Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA 90095, USA; Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA., Feng J; Department of Radiological Sciences, University of California, Los Angeles, Los Angeles, CA 90095, USA., Tran T; Department of Neurology, University of California, Los Angeles, Los Angeles, CA 90095, USA., Tozzo V; Department of Computational Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA., Queen KJ; Department of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA., Mootor MFE; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Urology, University of California, Los Angeles, Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA 90095, USA., Patil V; Department of Neurology, University of California, Los Angeles, Los Angeles, CA 90095, USA., Broudy ME; UCLA Health Information Technology, Office of Health Informatics and Analytics, University of California, Los Angeles, Los Angeles, CA 90095, USA., Tung P; UCLA Health Information Technology, Office of Health Informatics and Analytics, University of California, Los Angeles, Los Angeles, CA 90095, USA., Alam S; UCLA Health Information Technology, Office of Health Informatics and Analytics, University of California, Los Angeles, Los Angeles, CA 90095, USA., Martinez DB; UCLA Health Information Technology, Office of Health Informatics and Analytics, University of California, Los Angeles, Los Angeles, CA 90095, USA., Patel Y; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Urology, University of California, Los Angeles, Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA 90095, USA; Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA., Caggiano C; Institute for Genomic Health, Icahn School of Medicine at Mount Sinai, New York, NY 10027, USA., Zeltser N; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Urology, University of California, Los Angeles, Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA 90095, USA., Hugh-White R; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Urology, University of California, Los Angeles, Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA 90095, USA; Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA., Arbet J; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Urology, University of California, Los Angeles, Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA 90095, USA., Shemirani R; Institute for Genomic Health, Icahn School of Medicine at Mount Sinai, New York, NY 10027, USA., Tian M; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Urology, University of California, Los Angeles, Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA 90095, USA; Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA., Thapaliya P; UCLA Health Information Technology, Office of Health Informatics and Analytics, University of California, Los Angeles, Los Angeles, CA 90095, USA., Eloyan L; UCLA Health Information Technology, Office of Health Informatics and Analytics, University of California, Los Angeles, Los Angeles, CA 90095, USA., Chen LO; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Neurology, University of California, Los Angeles, Los Angeles, CA 90095, USA., Lapinska S; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Ariannejad M; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA 90095, USA., Lajonchere C; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Neurology, University of California, Los Angeles, Los Angeles, CA 90095, USA., Kenny EE; Institute for Genomic Health, Icahn School of Medicine at Mount Sinai, New York, NY 10027, USA; Center for Translational Genomics, Icahn School of Medicine, New York, NY 10027, USA; Division of Genomic Medicine, Department of Medicine, Icahn School of Medicine, New York, NY 10027, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine, New York, NY 10027, USA., Pasaniuc B; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Bui AAT; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Radiological Sciences, University of California, Los Angeles, Los Angeles, CA 90095, USA., Arboleda VA; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Computational Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA., Chang TS; Department of Neurology, University of California, Los Angeles, Los Angeles, CA 90095, USA., Zaitlen N; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Neurology, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Computational Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA., Spellman PT; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address: pspellman@mednet.ucla.edu., Boutros PC; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Urology, University of California, Los Angeles, Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA 90095, USA; Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA. Electronic address: pboutros@sbpdiscovery.org., Geschwind DH; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Neurology, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address: dhg@mednet.ucla.edu.
Corporate Authors: UCLA Precision Health Data Discovery Repository Working Group, UCLA Precision Health ATLAS Working Group, UCLA Health IT HPC Team, Regeneron Genetics Center
Source: Cell [Cell] 2026 Apr 30; Vol. 189 (9), pp. 2533-2555.e31. Date of Electronic Publication: 2026 Mar 27.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
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Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Computational Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.<br /><searchLink fieldCode="AU" term="%22Chang+TS%22">Chang TS</searchLink>; Department of Neurology, University of California, Los Angeles, Los Angeles, CA 90095, USA.<br /><searchLink fieldCode="AU" term="%22Zaitlen+N%22">Zaitlen N</searchLink>; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Neurology, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Computational Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.<br /><searchLink fieldCode="AU" term="%22Spellman+PT%22">Spellman PT</searchLink>; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA; Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA. 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          Name:
            NameFull: Chang TS
      – PersonEntity:
          Name:
            NameFull: Zaitlen N
      – PersonEntity:
          Name:
            NameFull: Spellman PT
      – PersonEntity:
          Name:
            NameFull: Boutros PC
      – PersonEntity:
          Name:
            NameFull: Geschwind DH
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 30
              M: 04
              Text: 2026 Apr 30
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1097-4172
          Numbering:
            – Type: volume
              Value: 189
            – Type: issue
              Value: 9
          Titles:
            – TitleFull: Cell
              Type: main
ResultId 1