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Development and validation of clinical criteria for the definition of disease activity in adult-onset Still's disease: a cohort study.

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Title: Development and validation of clinical criteria for the definition of disease activity in adult-onset Still's disease: a cohort study.
Authors: Ruscitti P; Division of Rheumatology, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy. Electronic address: piero.ruscitti@univaq.it., Stamm T; Institute of Outcomes Research, Center for Medical Data Science, Medical University of Vienna and Ludwig Boltzmann Institute for Arthritis and Rehabilitation, Vienna, Austria., Ritschl V; Institute of Outcomes Research, Center for Medical Data Science, Medical University of Vienna and Ludwig Boltzmann Institute for Arthritis and Rehabilitation, Vienna, Austria., Mitrovic S; Rheumatology Department, Pitié-Salpêtrière Hospital, Sorbonne University-AP-HP, Paris, France; INSERM UMRS959 Immunology-Immunopathology-Immunotherapy (i3), Sorbonne University, Paris, France; CEREMAIA Reference Center (ERN RITA), Paris, France., Girard-Guyonvarc'h C; Division of Rheumatology, Department of Medicine, University Hospital of Geneva and Faculty of Medicine University of Geneva, Geneva, Switzerland., Atzeni F; Rheumatology Unit, Department of Experimental and Internal Medicine, University of Messina, Messina, Italy., Bostrøm C; Department of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Stockholm, Sweden., Cantarini L; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese (ERN RITA Center), Siena, Italy., Caso F; Rheumatology Unit, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy., Cipriani P; Division of Rheumatology, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy., Ciccia F; Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', Naples, Italy., Gattorno M; IRCCS Istituto Giannina Gaslini, UOC Reumatologia e Malattie Autoinfiammatorie, Genoa, Italy., Guggino G; Rheumatology Section, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University Hospital P Giaccone, University of Palermo, Palermo, Italy., Guillemin F; Université de Lorraine, INSERM, UMR 1319 INSPIIRE, Nancy, France; CHRU Nancy, INSERM, Université de Lorraine, CIC-Clinical Epidemiology, Nancy, France., Krusche M; III Department of Medicine, Division of Rheumatology and Systemic Inflammatory Diseases, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Llorca J; Epidemiology, CIBER Epidemiología y Salud Pública (CIBERESP) and Department of Medical and Surgical Sciences, University of Cantabria, Santander, Spain; CARMA Project Collaborative Group, Madrid, Spain., Montecucco C; Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy; Division of Rheumatology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Perosa F; Rheumatic and Systemic Autoimmune Diseases Unit, Department of Interdisciplinary Medicine (DIM), University of Bari Medical School, Bari, Italy., Quartier P; Department of Interdisciplinary Medicine, Université Paris-Cité, Paris, France; Reference Centre for Rheumatic, Autoimmune Diseases, Interferonopathies and Systemic Inflammatory Diseases in Children (RAISE), Pediatric Immunology, Hematology and Rheumatology Unit, Necker Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France., Ravelli A; Dipartimento di Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno-Infantili (DINOGMI), Università degli Studi di Genova and Direzione Scientifica, IRCCS Istituto Giannina Gaslini, Genoa, Italy., Rosine N; Institut Pasteur, Université de Paris, Immunoregulation Unit, Department of Immunology, Paris, France., Wieczorek M; Swiss Centre of Expertise in Life Course Research LIVES, Lausanne and Geneva, Geneva, Switzerland., Wilhelmer TC; EULAR Research Partner, EULAR PARE, Zurich, Switzerland., Gonzalez-Gay MÁ; Division of Rheumatology, IIS-Fundación Jiménez Díaz, Madrid, Spain; Medicine and Psychiatry Department, University of Cantabria, Santander, Spain., Gabay C; Division of Rheumatology, Department of Medicine, University Hospital of Geneva and Faculty of Medicine University of Geneva, Geneva, Switzerland., Fautrel B; Rheumatology Department, Pitié-Salpêtrière Hospital, Sorbonne University-AP-HP, Paris, France; CEREMAIA Reference Center (ERN RITA), Paris, France; INSERM UMR S1136, Pierre Louis Institute of Epidemiology and Public Health, Paris, France; CRI-IMIDATE Clinical Research Network, Paris, France., Feist E; Department of Rheumatology, Helios Clinic, Magdeburg, Germany; Department of Experimental Rheumatology, Otto-von-Guericke University, Magdeburg, Germany; Department of Rheumatology and Clinical Immunology, Charité Universitätsmedizin Berlin, Berlin, Germany., Giacomelli R; Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy; Research and Clinical Unit of Immunorheumatology, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy. Electronic address: r.giacomelli@policlinicocampus.it.
Corporate Authors: CONSIDER trial study group, GIRRCS-AOSD research group
Source: The Lancet. Rheumatology [Lancet Rheumatol] 2026 Jun; Vol. 8 (6), pp. e451-e460. Date of Electronic Publication: 2026 Mar 25.
Publication Type: Journal Article; Validation Study
Journal Info: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101765308 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2665-9913 (Electronic) Linking ISSN: 26659913 NLM ISO Abbreviation: Lancet Rheumatol Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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  Data: Development and validation of clinical criteria for the definition of disease activity in adult-onset Still's disease: a cohort study.
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  Data: <searchLink fieldCode="AU" term="%22Ruscitti+P%22">Ruscitti P</searchLink>; Division of Rheumatology, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy. Electronic address: piero.ruscitti@univaq.it.<br /><searchLink fieldCode="AU" term="%22Stamm+T%22">Stamm T</searchLink>; Institute of Outcomes Research, Center for Medical Data Science, Medical University of Vienna and Ludwig Boltzmann Institute for Arthritis and Rehabilitation, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Ritschl+V%22">Ritschl V</searchLink>; Institute of Outcomes Research, Center for Medical Data Science, Medical University of Vienna and Ludwig Boltzmann Institute for Arthritis and Rehabilitation, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Mitrovic+S%22">Mitrovic S</searchLink>; Rheumatology Department, Pitié-Salpêtrière Hospital, Sorbonne University-AP-HP, Paris, France; INSERM UMRS959 Immunology-Immunopathology-Immunotherapy (i3), Sorbonne University, Paris, France; CEREMAIA Reference Center (ERN RITA), Paris, France.<br /><searchLink fieldCode="AU" term="%22Girard-Guyonvarc'h+C%22">Girard-Guyonvarc'h C</searchLink>; Division of Rheumatology, Department of Medicine, University Hospital of Geneva and Faculty of Medicine University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Atzeni+F%22">Atzeni F</searchLink>; Rheumatology Unit, Department of Experimental and Internal Medicine, University of Messina, Messina, Italy.<br /><searchLink fieldCode="AU" term="%22Bostrøm+C%22">Bostrøm C</searchLink>; Department of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Cantarini+L%22">Cantarini L</searchLink>; Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy; Azienda Ospedaliero-Universitaria Senese (ERN RITA Center), Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Caso+F%22">Caso F</searchLink>; Rheumatology Unit, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Cipriani+P%22">Cipriani P</searchLink>; Division of Rheumatology, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.<br /><searchLink fieldCode="AU" term="%22Ciccia+F%22">Ciccia F</searchLink>; Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Gattorno+M%22">Gattorno M</searchLink>; IRCCS Istituto Giannina Gaslini, UOC Reumatologia e Malattie Autoinfiammatorie, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Guggino+G%22">Guggino G</searchLink>; Rheumatology Section, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University Hospital P Giaccone, University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Guillemin+F%22">Guillemin F</searchLink>; Université de Lorraine, INSERM, UMR 1319 INSPIIRE, Nancy, France; CHRU Nancy, INSERM, Université de Lorraine, CIC-Clinical Epidemiology, Nancy, France.<br /><searchLink fieldCode="AU" term="%22Krusche+M%22">Krusche M</searchLink>; III Department of Medicine, Division of Rheumatology and Systemic Inflammatory Diseases, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Llorca+J%22">Llorca J</searchLink>; Epidemiology, CIBER Epidemiología y Salud Pública (CIBERESP) and Department of Medical and Surgical Sciences, University of Cantabria, Santander, Spain; CARMA Project Collaborative Group, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Montecucco+C%22">Montecucco C</searchLink>; Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy; Division of Rheumatology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Perosa+F%22">Perosa F</searchLink>; Rheumatic and Systemic Autoimmune Diseases Unit, Department of Interdisciplinary Medicine (DIM), University of Bari Medical School, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Quartier+P%22">Quartier P</searchLink>; Department of Interdisciplinary Medicine, Université Paris-Cité, Paris, France; Reference Centre for Rheumatic, Autoimmune Diseases, Interferonopathies and Systemic Inflammatory Diseases in Children (RAISE), Pediatric Immunology, Hematology and Rheumatology Unit, Necker Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.<br /><searchLink fieldCode="AU" term="%22Ravelli+A%22">Ravelli A</searchLink>; Dipartimento di Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno-Infantili (DINOGMI), Università degli Studi di Genova and Direzione Scientifica, IRCCS Istituto Giannina Gaslini, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Rosine+N%22">Rosine N</searchLink>; Institut Pasteur, Université de Paris, Immunoregulation Unit, Department of Immunology, Paris, France.<br /><searchLink fieldCode="AU" term="%22Wieczorek+M%22">Wieczorek M</searchLink>; Swiss Centre of Expertise in Life Course Research LIVES, Lausanne and Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wilhelmer+TC%22">Wilhelmer TC</searchLink>; EULAR Research Partner, EULAR PARE, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Gonzalez-Gay+MÁ%22">Gonzalez-Gay MÁ</searchLink>; Division of Rheumatology, IIS-Fundación Jiménez Díaz, Madrid, Spain; Medicine and Psychiatry Department, University of Cantabria, Santander, Spain.<br /><searchLink fieldCode="AU" term="%22Gabay+C%22">Gabay C</searchLink>; Division of Rheumatology, Department of Medicine, University Hospital of Geneva and Faculty of Medicine University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Fautrel+B%22">Fautrel B</searchLink>; Rheumatology Department, Pitié-Salpêtrière Hospital, Sorbonne University-AP-HP, Paris, France; CEREMAIA Reference Center (ERN RITA), Paris, France; INSERM UMR S1136, Pierre Louis Institute of Epidemiology and Public Health, Paris, France; CRI-IMIDATE Clinical Research Network, Paris, France.<br /><searchLink fieldCode="AU" term="%22Feist+E%22">Feist E</searchLink>; Department of Rheumatology, Helios Clinic, Magdeburg, Germany; Department of Experimental Rheumatology, Otto-von-Guericke University, Magdeburg, Germany; Department of Rheumatology and Clinical Immunology, Charité Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Giacomelli+R%22">Giacomelli R</searchLink>; Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy; Research and Clinical Unit of Immunorheumatology, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy. Electronic address: r.giacomelli@policlinicocampus.it.
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  Data: <searchLink fieldCode="CA" term="%22CONSIDER+trial+study+group%22">CONSIDER trial study group</searchLink><br /><searchLink fieldCode="CA" term="%22GIRRCS-AOSD+research+group%22">GIRRCS-AOSD research group</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22101765308%22">The Lancet. Rheumatology</searchLink> [Lancet Rheumatol] 2026 Jun; Vol. 8 (6), pp. e451-e460. <i>Date of Electronic Publication: </i>2026 Mar 25.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Ltd%22">Elsevier Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101765308 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2665-9913 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226659913%22">26659913 </searchLink><i>NLM ISO Abbreviation: </i>Lancet Rheumatol <i>Subsets: </i>MEDLINE
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