Development and Validation of the Risk of Exacerbation in Severe Asthma (RESA) Model.

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Title: Development and Validation of the Risk of Exacerbation in Severe Asthma (RESA) Model.
Authors: Chen W; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore. Electronic address: wenjiach@nus.edu.sg., Lee TY; Department of Adult Neurosurgery, Stanford University, Stanford, Calif., Price D; Optimum Patient Care Global, Cambridge, United Kingdom; Observational and Pragmatic Research Institute, Singapore, Singapore; Centre of Academic Primary Care, Division of Applied Health Sciences, University of Aberdeen, Aberdeen, United Kingdom., Beasley R; Medical Research Institute of New Zealand, Wellington, New Zealand., Janson C; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Siyue MK; Duke-NUS Medical School, Singapore, Singapore; Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore, Singapore., Yadav CP; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore., Müllerová H; Respiratory & Immunology, Medical and Payer Evidence Strategy, BioPharmaceuticals Medical, AstraZeneca, Cambridge, United Kingdom., Burgel PR; Department of Respiratory Medicine, Cochin Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France; Institut Cochin, Inserm U1016, Université Paris Cité, Paris, France., Tran TN; BioPharmaceuticals Medical, AstraZeneca, Gaithersburg, Md., Emmanuel B; BioPharmaceuticals Medical, AstraZeneca, Gaithersburg, Md., Wang E; Division of Allergy & Clinical Immunology, Department of Medicine, National Jewish Health, Denver, Colo; Division of Allergy & Clinical Immunology, Department of Medicine, University of Colorado School of Medicine, Aurora, Colo., Wechsler ME; NJH Cohen Family Asthma Institute, Department of Medicine, National Jewish Health, Denver, Colo., Jackson DJ; Guy's Severe Asthma Centre, Guy's and St Thomas' NHS Trust, London, United Kingdom; School of Immunology & Microbial Sciences, King's College London, London, United Kingdom., Busby J; Centre for Public Health, Queen's University Belfast, Belfast, Northern Ireland., Heaney LG; Wellcome-Wolfson Centre for Experimental Medicine, Queen's University Belfast, Belfast, Northern Ireland., Pfeffer PE; Department of Respiratory Medicine, Barts Health NHS Trust, London, United Kingdom; Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom., Mahboub B; College of Medicine, University of Sharjah, Sharjah, United Arab Emirates; Rashid Hospital, Dubai Health Authority, Dubai, United Arab Emirates., Perng DW; Division of Clinical Respiratory Physiology, Chest Department, Taipei Veterans General Hospital, Taipei City, Taiwan; COPD Assembly of the Asian Pacific Society of Respirology, Tokyo, Japan., Cosio BG; Son Espases University Hospital-IdISBa-Ciberes, Mallorca, Spain., Perez-de-Llano L; Pneumology Service, Lucus Augusti University Hospital, EOXI Lugo, Monforte, Cervo, Spain., Al-Lehebi R; Department of Pulmonology, King Fahad Medical City, Riyadh, Saudi Arabia; College of Medicine, Alfaisal University, Riyadh, Saudi Arabia., Larenas-Linnemann D; Center of Excellence in Asthma and Allergy, Hospital Médica Sur, Mexico City, Mexico., Al-Ahmad M; Microbiology Department, College of Medicine, Kuwait University, Al-Rashed Allergy Center, Ministry of Health, Kuwait City, Kuwait., Rhee CK; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea., Iwanaga T; Center for General Medical Education and Clinical Training, Kindai University Hospital, Osakasayama, Japan., Heffler E; Personalized Medicine, Asthma and Allergy, IRCCS HumanitasResearch Hospital, Rozzano, Milan, Italy; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy., Canonica GW; Clinical Research Centre, Smurfit Building Beaumont Hospital, Department of Respiratory Medicine, RCSI, Dublin, Ireland; Division of Infection, Immunity & Respiratory Medicine, University of Manchester, Manchester, United Kingdom., Costello R; Clinical Research Centre, Smurfit Building Beaumont Hospital, Department of Respiratory Medicine, RCSI, Dublin, Ireland., Papadopoulos NG; Division of Infection, Immunity & Respiratory Medicine, University of Manchester, Manchester, United Kingdom; Allergy Department, 2nd Pediatric Clinic, University of Athens, Athens, Greece., Papaioannou AI; 2nd Respiratory Medicine Department, National and Kapodistrian University of Athens Medical School, Attikon University Hospital, Athens, Greece., Porsbjerg CM; Respiratory Research Unit, Department of Respiratory Medicine and Infectious Diseases, Bispebjerg University Hospital, Copenhagen, Denmark., Torres-Duque CA; CINEUMO, Respiratory Research Center, Fundación Neumológica Colombiana, Bogotá, Colombia., Christoff GC; Medical University-Sofia, Faculty of Public Health, Sofia, Bulgaria., Popov TA; University Hospital 'Sv. Ivan Rilski, ' Sofia, Bulgaria., Hew M; Allergy, Asthma & Clinical Immunology Service, Alfred Health, Melbourne, Victoria, Australia; Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia., Peters M; Department of Thoracic Medicine, Concord Hospital, Sydney, New South Wales, Australia., Gibson PG; Australian Severe Asthma Network, Priority Research Centre for Healthy Lungs, University of Newcastle, Newcastle, New South Wales, Australia; Hunter Medical Research Institute, Department of Respiratory and Sleep Medicine, John Hunter Hospital, New Lambton Heights, New South Wales, Australia., Maspero J; Clinical Research for Allergy and Respiratory Medicine, CIDEA Foundation, Buenos Aires, Argentina; University Career of Specialists in Allergy and Clinical Immunology, Buenos Aires University School of Medicine, Buenos Aires, Argentina., Bergeron C; Centre for Lung Health, Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada., Cerda S; Medical Specialties Unit, Secretary of National Defense, Mexico City, Mexico., Contreras EA; Mexican Council of Clinical Immunology and Allergy, Mexico City Office, Mexico City, Mexico; Department of Allergy and Clinical Immunology, Lic. Adolfo López Mateos Regional Hospital of the Institute of Security and Social Services for State Workers (ISSSTE), Mexico City, Mexico., Sadatsafavi M; Respiratory Evaluation Sciences Program, Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
Source: The journal of allergy and clinical immunology. In practice [J Allergy Clin Immunol Pract] 2026 Jul; Vol. 14 (7), pp. 1589-1600. Date of Electronic Publication: 2026 Mar 27.
Publication Type: Journal Article; Observational Study; Validation Study
Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101597220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2201 (Electronic) NLM ISO Abbreviation: J Allergy Clin Immunol Pract Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Development and Validation of the Risk of Exacerbation in Severe Asthma (RESA) Model.
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Electronic address: wenjiach@nus.edu.sg.<br /><searchLink fieldCode="AU" term="%22Lee+TY%22">Lee TY</searchLink>; Department of Adult Neurosurgery, Stanford University, Stanford, Calif.<br /><searchLink fieldCode="AU" term="%22Price+D%22">Price D</searchLink>; Optimum Patient Care Global, Cambridge, United Kingdom; Observational and Pragmatic Research Institute, Singapore, Singapore; Centre of Academic Primary Care, Division of Applied Health Sciences, University of Aberdeen, Aberdeen, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Beasley+R%22">Beasley R</searchLink>; Medical Research Institute of New Zealand, Wellington, New Zealand.<br /><searchLink fieldCode="AU" term="%22Janson+C%22">Janson C</searchLink>; Department of Medical Sciences, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Siyue+MK%22">Siyue MK</searchLink>; Duke-NUS Medical School, Singapore, Singapore; Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Yadav+CP%22">Yadav CP</searchLink>; 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Personalized Medicine, Asthma and Allergy, IRCCS HumanitasResearch Hospital, Rozzano, Milan, Italy; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Canonica+GW%22">Canonica GW</searchLink>; Clinical Research Centre, Smurfit Building Beaumont Hospital, Department of Respiratory Medicine, RCSI, Dublin, Ireland; Division of Infection, Immunity & Respiratory Medicine, University of Manchester, Manchester, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Costello+R%22">Costello R</searchLink>; Clinical Research Centre, Smurfit Building Beaumont Hospital, Department of Respiratory Medicine, RCSI, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Papadopoulos+NG%22">Papadopoulos NG</searchLink>; Division of Infection, Immunity & Respiratory Medicine, University of Manchester, Manchester, United Kingdom; Allergy Department, 2nd Pediatric Clinic, University of Athens, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Papaioannou+AI%22">Papaioannou AI</searchLink>; 2nd Respiratory Medicine Department, National and Kapodistrian University of Athens Medical School, Attikon University Hospital, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Porsbjerg+CM%22">Porsbjerg CM</searchLink>; Respiratory Research Unit, Department of Respiratory Medicine and Infectious Diseases, Bispebjerg University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Torres-Duque+CA%22">Torres-Duque CA</searchLink>; CINEUMO, Respiratory Research Center, Fundación Neumológica Colombiana, Bogotá, Colombia.<br /><searchLink fieldCode="AU" term="%22Christoff+GC%22">Christoff GC</searchLink>; Medical University-Sofia, Faculty of Public Health, Sofia, Bulgaria.<br /><searchLink fieldCode="AU" term="%22Popov+TA%22">Popov TA</searchLink>; University Hospital 'Sv. 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