HOXA9 orchestrates EMT and metastasis in oral cancer via transcriptional activation of vimentin and β-catenin signaling.

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Title: HOXA9 orchestrates EMT and metastasis in oral cancer via transcriptional activation of vimentin and β-catenin signaling.
Authors: Shenoy US; Department of Cell and Molecular Biology, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India., Adiga D; Department of Cell and Molecular Biology, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India., Basavarajappa DS; Department of Cell and Molecular Biology, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India., Kumar NAN; Department of Surgical Oncology, Kasturba Medical College and Hospital, Manipal Academy of Higher Education, Manipal, Karnataka, India., Kudva A; Department of Oral and Maxillofacial Surgery, Kasturba Medical College and Hospital, Manipal Academy of Higher Education, Manipal, Karnataka, India., Kunnumakkara AB; Cancer Biology Laboratory, Department of Biosciences and Bioengineering, Indian Institute of Technology, Guwahati, Assam, India., Hunter KD; Liverpool Head and Neck Centre, Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK., Kabekkodu SP; Department of Cell and Molecular Biology, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India., Radhakrishnan R; Department of Oral and Maxillofacial Pathology and Oral Microbiology, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India. raghu.ar@manipal.edu.; Academic Unit of Oral and Maxillofacial Medicine and Pathology, School of Clinical Dentistry, University of Sheffield, Sheffield, UK. raghu.ar@manipal.edu.; Oral Biology and Pathology, Oman Dental College, Muscat, Oman. raghu.ar@manipal.edu.
Source: Cell death & disease [Cell Death Dis] 2026 Mar 28; Vol. 17 (1). Date of Electronic Publication: 2026 Mar 28.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: HOXA9 orchestrates EMT and metastasis in oral cancer via transcriptional activation of vimentin and β-catenin signaling.
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  Data: <searchLink fieldCode="AU" term="%22Shenoy+US%22">Shenoy US</searchLink>; Department of Cell and Molecular Biology, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.<br /><searchLink fieldCode="AU" term="%22Adiga+D%22">Adiga D</searchLink>; Department of Cell and Molecular Biology, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.<br /><searchLink fieldCode="AU" term="%22Basavarajappa+DS%22">Basavarajappa DS</searchLink>; Department of Cell and Molecular Biology, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.<br /><searchLink fieldCode="AU" term="%22Kumar+NAN%22">Kumar NAN</searchLink>; Department of Surgical Oncology, Kasturba Medical College and Hospital, Manipal Academy of Higher Education, Manipal, Karnataka, India.<br /><searchLink fieldCode="AU" term="%22Kudva+A%22">Kudva A</searchLink>; Department of Oral and Maxillofacial Surgery, Kasturba Medical College and Hospital, Manipal Academy of Higher Education, Manipal, Karnataka, India.<br /><searchLink fieldCode="AU" term="%22Kunnumakkara+AB%22">Kunnumakkara AB</searchLink>; Cancer Biology Laboratory, Department of Biosciences and Bioengineering, Indian Institute of Technology, Guwahati, Assam, India.<br /><searchLink fieldCode="AU" term="%22Hunter+KD%22">Hunter KD</searchLink>; Liverpool Head and Neck Centre, Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Kabekkodu+SP%22">Kabekkodu SP</searchLink>; Department of Cell and Molecular Biology, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.<br /><searchLink fieldCode="AU" term="%22Radhakrishnan+R%22">Radhakrishnan R</searchLink>; Department of Oral and Maxillofacial Pathology and Oral Microbiology, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India. raghu.ar@manipal.edu.; Academic Unit of Oral and Maxillofacial Medicine and Pathology, School of Clinical Dentistry, University of Sheffield, Sheffield, UK. raghu.ar@manipal.edu.; Oral Biology and Pathology, Oman Dental College, Muscat, Oman. raghu.ar@manipal.edu.
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  Data: <searchLink fieldCode="JN" term="%22101524092%22">Cell death & disease</searchLink> [Cell Death Dis] 2026 Mar 28; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Mar 28.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101524092 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-4889 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Death Dis <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41419-026-08664-7
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        Text: English
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              Text: 2026 Mar 28
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