Personalized hemodynamic management targeting preoperative baseline cardiac index in high-risk patients having major abdominal surgery: rationale and design of the international multicenter randomized PELICAN trial.

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Title: Personalized hemodynamic management targeting preoperative baseline cardiac index in high-risk patients having major abdominal surgery: rationale and design of the international multicenter randomized PELICAN trial.
Authors: Flick M; Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Aasvang EK; Department of Anaesthesiology, Centre for Cancer and Organ Diseases, Rigshospitalet, Copenhagen University Hospital, Copenhagen University, Copenhagen, Denmark., Eichlseder M; Division of Anaesthesiology and Intensive Care 1, Department of Anaesthesiology and Intensive Care, Medical University of Graz, Graz, Austria., Klimovic A; Department of Anesthesiology, Resuscitation and Intensive Care, Faculty of Medicine in Pilsen, Charles University, Prague, Czech Republic., Meidert AS; Department of Anaesthesiology, LMU University Hospital, LMU Munich, Munich, Germany., Meyhoff CS; Department of Anaesthesia and Intensive Care, Copenhagen University Hospital-Bispebjerg and Frederiksberg, Copenhagen, Denmark., Roth S; Department of Anesthesiology, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany., Steinhaus M; Department of Anesthesiology and Intensive Care, University of Lübeck and University Medical Center Schleswig-Holstein, Lübeck, Germany., Sort R; Department of Anaesthesiology, Copenhagen University Hospital - Amager and Hvidovre, Hvidovre, Denmark., Vives M; Department of Anesthesia & Critical Care, Clínica Universidad de Navarra, Pamplona, Spain., Vojnar B; Department of Anesthesiology and Intensive Care Medicine, University Hospital Giessen and Marburg, Campus Marburg and Philipps-University of Marburg, Marburg, Germany., Ziemann S; Department of Anaesthesiology, Medical Faculty, RWTH Aachen University Hospital, Aachen, Germany., Krause L; Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Vettorazzi E; Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Zapf A; Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Kouz K; Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; OUTCOMES RESEARCH Consortium, Houston, TX, USA., Saugel B; Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. bcs.muc@gmx.de.; OUTCOMES RESEARCH Consortium, Houston, TX, USA. bcs.muc@gmx.de.
Source: Trials [Trials] 2026 Mar 28; Vol. 27 (1). Date of Electronic Publication: 2026 Mar 28.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215 (Electronic) Linking ISSN: 17456215 NLM ISO Abbreviation: Trials Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Personalized hemodynamic management targeting preoperative baseline cardiac index in high-risk patients having major abdominal surgery: rationale and design of the international multicenter randomized PELICAN trial.
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  Data: <searchLink fieldCode="AU" term="%22Flick+M%22">Flick M</searchLink>; Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Aasvang+EK%22">Aasvang EK</searchLink>; Department of Anaesthesiology, Centre for Cancer and Organ Diseases, Rigshospitalet, Copenhagen University Hospital, Copenhagen University, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Eichlseder+M%22">Eichlseder M</searchLink>; Division of Anaesthesiology and Intensive Care 1, Department of Anaesthesiology and Intensive Care, Medical University of Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Klimovic+A%22">Klimovic A</searchLink>; Department of Anesthesiology, Resuscitation and Intensive Care, Faculty of Medicine in Pilsen, Charles University, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Meidert+AS%22">Meidert AS</searchLink>; Department of Anaesthesiology, LMU University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Meyhoff+CS%22">Meyhoff CS</searchLink>; Department of Anaesthesia and Intensive Care, Copenhagen University Hospital-Bispebjerg and Frederiksberg, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Roth+S%22">Roth S</searchLink>; Department of Anesthesiology, University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Steinhaus+M%22">Steinhaus M</searchLink>; Department of Anesthesiology and Intensive Care, University of Lübeck and University Medical Center Schleswig-Holstein, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Sort+R%22">Sort R</searchLink>; Department of Anaesthesiology, Copenhagen University Hospital - Amager and Hvidovre, Hvidovre, Denmark.<br /><searchLink fieldCode="AU" term="%22Vives+M%22">Vives M</searchLink>; Department of Anesthesia & Critical Care, Clínica Universidad de Navarra, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Vojnar+B%22">Vojnar B</searchLink>; Department of Anesthesiology and Intensive Care Medicine, University Hospital Giessen and Marburg, Campus Marburg and Philipps-University of Marburg, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Ziemann+S%22">Ziemann S</searchLink>; Department of Anaesthesiology, Medical Faculty, RWTH Aachen University Hospital, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Krause+L%22">Krause L</searchLink>; Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Vettorazzi+E%22">Vettorazzi E</searchLink>; Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Zapf+A%22">Zapf A</searchLink>; Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Kouz+K%22">Kouz K</searchLink>; Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; OUTCOMES RESEARCH Consortium, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Saugel+B%22">Saugel B</searchLink>; Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. bcs.muc@gmx.de.; OUTCOMES RESEARCH Consortium, Houston, TX, USA. bcs.muc@gmx.de.
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