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Real-world effectiveness and safety of zilucoplan in patients with anti-AChR myasthenia gravis: A retrospective cohort study in France.

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Title: Real-world effectiveness and safety of zilucoplan in patients with anti-AChR myasthenia gravis: A retrospective cohort study in France.
Authors: Tammam G; Reference Center for Neuromuscular Disorders, Peripheral Nervous System and Muscle Department, Nice University Hospital, Pasteur 2 Hospital, NICE, France., Slioui A; Reference Center for Neuromuscular Disorders, Peripheral Nervous System and Muscle Department, Nice University Hospital, Pasteur 2 Hospital, NICE, France., Friedman D; Department of Intensive Care, Raymond Poincaré Hospital, APHP University Versailles Saint Quentin-University Paris Saclay, PARIS, France., Acket B; Department of Neurology, Toulouse University Hospital, TOULOUSE, France., Cavalli M; Reference Center for Neuromuscular Disorders, Peripheral Nervous System and Muscle Department, Nice University Hospital, Pasteur 2 Hospital, NICE, France., Bresch S; Reference Center for Neuromuscular Disorders, Peripheral Nervous System and Muscle Department, Nice University Hospital, Pasteur 2 Hospital, NICE, France., Lagrange E; Reference Center for Neuromuscular Disorders, Grenoble University Hospital, GRENOBLE, France., Sole G; Reference Center for Neuromuscular Disorders, FILNEMUS, EURO-NMD, Neurology and Neuromuscular Diseases Department, Pellegrin Hospital, Bordeaux University Hospitals, BORDEAUX, France., Noury JB; INSERM Lymphocytes B, Autommunity and Immunotherapy UMR1227, University of Western Brittany, BREST, France.; Reference Center for Neuromuscular Disorders, FILNEMUS, Brest Regional University Hospital, BREST, France., Barbat Du Closel L; Reference Center for Neuromuscular Disorders, FILNEMUS, Neurology Department, La Timone Hospital University, MARSEILLE, France., Marois C; Sorbonne Université, AP-HP. Sorbonne Université, Hôpital de la Pitié-Salpêtrière, Médecine Intensive Réanimation à Orientation Neurologique, PARIS, France., Pakleza AN; Reference Center for Neuromuscular Disorders, FILNEMUS, Neurology Department, Strasbourg University Hospitals, STRASBOURG, France., Tard C; U1172, Reference Center for Neuromuscular Disorders, Neurology Department, Lille University Hospital, LILLE, France., Salort-Campana E; Reference Center for Neuromuscular Disorders, FILNEMUS, Neurology Department, La Timone Hospital University, MARSEILLE, France., Merle PE; Department of Clinical Neurophysiology, Amiens-Picardie University Hospital, AMIENS, France., Annane D; Department of Intensive Care, Raymond Poincaré Hospital, APHP University Versailles Saint Quentin-University Paris Saclay, PARIS, France., Attarian S; Reference Center for Neuromuscular Disorders, FILNEMUS, Neurology Department, La Timone Hospital University, MARSEILLE, France., Duval F; Reference Center for Neuromuscular Disorders, FILNEMUS, EURO-NMD, Neurology and Neuromuscular Diseases Department, Pellegrin Hospital, Bordeaux University Hospitals, BORDEAUX, France., Frachet S; Reference Center for Neuromuscular Disorders, FILNEMUS, Neurology Department, Neuropathies et Innovations Thérapeutiques (UR 20218 NEURIT), Limoges University Hospital, LIMOGES, France., Svahn J; Reference Center for Neuromuscular Disorders, Department of ENMG and Neuromuscular Disorders, P. Wertheimer Neurology Hospital, Hospices Civils de Lyon, LYON, France., Pegat A; Reference Center for Neuromuscular Disorders, Department of ENMG and Neuromuscular Disorders, P. Wertheimer Neurology Hospital, Hospices Civils de Lyon, LYON, France., Bouhour F; Reference Center for Neuromuscular Disorders, Department of ENMG and Neuromuscular Disorders, P. Wertheimer Neurology Hospital, Hospices Civils de Lyon, LYON, France., Taieb G; University of Montpellier, CNRS (IGF), Department of Neurology, Montpellier, University Hospital, MONTPELLIER, France., Praline J; Department of Neurophysiology, Orléans University Hospital, ORLEANS, France., Puma A; Reference Center for Neuromuscular Disorders, Peripheral Nervous System and Muscle Department, Nice University Hospital, Pasteur 2 Hospital, NICE, France., Fabry V; Reference Center for Neuromuscular Disorders, FILNEMUS, Neurology Department, Toulouse Purpan University Hospital, TOULOUSE, France., Villa L; Reference Center for Neuromuscular Disorders, Peripheral Nervous System and Muscle Department, Nice University Hospital, Pasteur 2 Hospital, NICE, France., Beltran S; ALS Centre, Neurology Department, Bretonneau Regional University Hospital, TOURS, France., Behin A; Reference Center for Neuromuscular Disorders, FILNEMUS, Neurology Department, Pitié-Salpêtrière Hospital, APHP, PARIS, France., Cintas P; Reference Center for Neuromuscular Disorders, FILNEMUS, Neurology Department, Toulouse Purpan University Hospital, TOULOUSE, France., Sacconi S; Reference Center for Neuromuscular Disorders, Peripheral Nervous System and Muscle Department, Nice University Hospital, Pasteur 2 Hospital, NICE, France.; University Cote d'Azur, Inserm, CNRS, Institute for Research on Cancer and Aging of Nice (IRCAN), Nice, France.
Source: Journal of neuromuscular diseases [J Neuromuscul Dis] 2026 Mar 29, pp. 22143602261437792. Date of Electronic Publication: 2026 Mar 29.
Publication Type: Journal Article
Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 101649948 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2214-3602 (Electronic) Linking ISSN: 22143599 NLM ISO Abbreviation: J Neuromuscul Dis Subsets: MEDLINE
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  Data: Real-world effectiveness and safety of zilucoplan in patients with anti-AChR myasthenia gravis: A retrospective cohort study in France.
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Wertheimer Neurology Hospital, Hospices Civils de Lyon, LYON, France.<br /><searchLink fieldCode="AU" term="%22Pegat+A%22">Pegat A</searchLink>; Reference Center for Neuromuscular Disorders, Department of ENMG and Neuromuscular Disorders, P. Wertheimer Neurology Hospital, Hospices Civils de Lyon, LYON, France.<br /><searchLink fieldCode="AU" term="%22Bouhour+F%22">Bouhour F</searchLink>; Reference Center for Neuromuscular Disorders, Department of ENMG and Neuromuscular Disorders, P. Wertheimer Neurology Hospital, Hospices Civils de Lyon, LYON, France.<br /><searchLink fieldCode="AU" term="%22Taieb+G%22">Taieb G</searchLink>; University of Montpellier, CNRS (IGF), Department of Neurology, Montpellier, University Hospital, MONTPELLIER, France.<br /><searchLink fieldCode="AU" term="%22Praline+J%22">Praline J</searchLink>; Department of Neurophysiology, Orléans University Hospital, ORLEANS, France.<br /><searchLink fieldCode="AU" term="%22Puma+A%22">Puma A</searchLink>; Reference Center for Neuromuscular Disorders, Peripheral Nervous System and Muscle Department, Nice University Hospital, Pasteur 2 Hospital, NICE, France.<br /><searchLink fieldCode="AU" term="%22Fabry+V%22">Fabry V</searchLink>; Reference Center for Neuromuscular Disorders, FILNEMUS, Neurology Department, Toulouse Purpan University Hospital, TOULOUSE, France.<br /><searchLink fieldCode="AU" term="%22Villa+L%22">Villa L</searchLink>; Reference Center for Neuromuscular Disorders, Peripheral Nervous System and Muscle Department, Nice University Hospital, Pasteur 2 Hospital, NICE, France.<br /><searchLink fieldCode="AU" term="%22Beltran+S%22">Beltran S</searchLink>; ALS Centre, Neurology Department, Bretonneau Regional University Hospital, TOURS, France.<br /><searchLink fieldCode="AU" term="%22Behin+A%22">Behin A</searchLink>; Reference Center for Neuromuscular Disorders, FILNEMUS, Neurology Department, Pitié-Salpêtrière Hospital, APHP, PARIS, France.<br /><searchLink fieldCode="AU" term="%22Cintas+P%22">Cintas P</searchLink>; Reference Center for Neuromuscular Disorders, FILNEMUS, Neurology Department, Toulouse Purpan University Hospital, TOULOUSE, France.<br /><searchLink fieldCode="AU" term="%22Sacconi+S%22">Sacconi S</searchLink>; Reference Center for Neuromuscular Disorders, Peripheral Nervous System and Muscle Department, Nice University Hospital, Pasteur 2 Hospital, NICE, France.; University Cote d'Azur, Inserm, CNRS, Institute for Research on Cancer and Aging of Nice (IRCAN), Nice, France.
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