Independent and interactive contributions of white matter hyperintensities and Alzheimer's disease imaging and plasma biomarkers to cognitive decline in older adults without dementia.
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| Title: | Independent and interactive contributions of white matter hyperintensities and Alzheimer's disease imaging and plasma biomarkers to cognitive decline in older adults without dementia. |
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| Authors: | Bachmann D; Institute for Regenerative Medicine, University of Zurich, Wagistrasse 12, Schlieren, 8952, Switzerland. dario.bachmann@irem.uzh.ch., Gericke C; Institute for Regenerative Medicine, University of Zurich, Wagistrasse 12, Schlieren, 8952, Switzerland., Wybitul M; Institute for Regenerative Medicine, University of Zurich, Wagistrasse 12, Schlieren, 8952, Switzerland., Saake A; Institute for Regenerative Medicine, University of Zurich, Wagistrasse 12, Schlieren, 8952, Switzerland., Studer S; Institute for Regenerative Medicine, University of Zurich, Wagistrasse 12, Schlieren, 8952, Switzerland., Rauen K; Institute for Regenerative Medicine, University of Zurich, Wagistrasse 12, Schlieren, 8952, Switzerland.; Neuroscience Center Zurich, University of Zurich, Zurich, 8057, Switzerland., Gruber E; Institute for Regenerative Medicine, University of Zurich, Wagistrasse 12, Schlieren, 8952, Switzerland., Buchmann A; Institute for Regenerative Medicine, University of Zurich, Wagistrasse 12, Schlieren, 8952, Switzerland., Hüllner M; Department of Nuclear Medicine, University Hospital of Zurich, University of Zurich, Zurich, 8091, Switzerland., Blennow K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Mölndal, S-43180, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, S- 43180, Sweden.; Paris Brain Institute, ICM, Pitié-Salpêtrière Hospital, Sorbonne University, Paris, 75013, France.; Neurodegenerative Disorder Research Center, Division of Life Sciences and Medicine, Department of Neurology, Institute on Aging and Brain Disorders, University of Science and Technology of China and First Affiliated Hospital of USTC, Hefei, 230026, P.R. China., Zetterberg H; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Mölndal, S-43180, Sweden.; Neurodegenerative Disorder Research Center, Division of Life Sciences and Medicine, Department of Neurology, Institute on Aging and Brain Disorders, University of Science and Technology of China and First Affiliated Hospital of USTC, Hefei, 230026, P.R. China.; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK.; UK Dementia Research Institute at UCL, London, WC1N 3BG, UK.; Hong Kong Center for Neurodegenerative Diseases, Clear Water Bay, Hong Kong, China.; Wisconsin Alzheimer's Disease Research Center, School of Medicine and Public Health, University of Wisconsin, University of Wisconsin-Madison, Madison, WI, 53792, USA., Nitsch RM; Institute for Regenerative Medicine, University of Zurich, Wagistrasse 12, Schlieren, 8952, Switzerland.; Neurimmune AG, Zurich, 8952, Switzerland., Hock C; Institute for Regenerative Medicine, University of Zurich, Wagistrasse 12, Schlieren, 8952, Switzerland.; Neurimmune AG, Zurich, 8952, Switzerland.; Center for Prevention and Dementia Therapy, University of Zurich, Zurich, 8952, Switzerland., Treyer V; Institute for Regenerative Medicine, University of Zurich, Wagistrasse 12, Schlieren, 8952, Switzerland.; Department of Nuclear Medicine, University Hospital of Zurich, University of Zurich, Zurich, 8091, Switzerland.; Center for Prevention and Dementia Therapy, University of Zurich, Zurich, 8952, Switzerland., Gietl A; Institute for Regenerative Medicine, University of Zurich, Wagistrasse 12, Schlieren, 8952, Switzerland.; Center for Prevention and Dementia Therapy, University of Zurich, Zurich, 8952, Switzerland.; Department of Geriatric Psychiatry, Psychiatric Hospital Zurich, Zurich, 8008, Switzerland. |
| Source: | Alzheimer's research & therapy [Alzheimers Res Ther] 2026 Mar 30; Vol. 18 (1). Date of Electronic Publication: 2026 Mar 30. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101511643 Publication Model: Electronic Cited Medium: Internet ISSN: 1758-9193 (Electronic) NLM ISO Abbreviation: Alzheimers Res Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41906163 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Independent and interactive contributions of white matter hyperintensities and Alzheimer's disease imaging and plasma biomarkers to cognitive decline in older adults without dementia. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Bachmann+D%22">Bachmann D</searchLink>; Institute for Regenerative Medicine, University of Zurich, Wagistrasse 12, Schlieren, 8952, Switzerland. dario.bachmann@irem.uzh.ch.<br /><searchLink fieldCode="AU" term="%22Gericke+C%22">Gericke C</searchLink>; Institute for Regenerative Medicine, University of Zurich, Wagistrasse 12, Schlieren, 8952, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wybitul+M%22">Wybitul M</searchLink>; Institute for Regenerative Medicine, University of Zurich, Wagistrasse 12, Schlieren, 8952, Switzerland.<br /><searchLink fieldCode="AU" term="%22Saake+A%22">Saake A</searchLink>; Institute for Regenerative Medicine, University of Zurich, Wagistrasse 12, Schlieren, 8952, Switzerland.<br /><searchLink fieldCode="AU" term="%22Studer+S%22">Studer S</searchLink>; Institute for Regenerative Medicine, University of Zurich, Wagistrasse 12, Schlieren, 8952, Switzerland.<br /><searchLink fieldCode="AU" term="%22Rauen+K%22">Rauen K</searchLink>; Institute for Regenerative Medicine, University of Zurich, Wagistrasse 12, Schlieren, 8952, Switzerland.; Neuroscience Center Zurich, University of Zurich, Zurich, 8057, Switzerland.<br /><searchLink fieldCode="AU" term="%22Gruber+E%22">Gruber E</searchLink>; Institute for Regenerative Medicine, University of Zurich, Wagistrasse 12, Schlieren, 8952, Switzerland.<br /><searchLink fieldCode="AU" term="%22Buchmann+A%22">Buchmann A</searchLink>; Institute for Regenerative Medicine, University of Zurich, Wagistrasse 12, Schlieren, 8952, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hüllner+M%22">Hüllner M</searchLink>; Department of Nuclear Medicine, University Hospital of Zurich, University of Zurich, Zurich, 8091, Switzerland.<br /><searchLink fieldCode="AU" term="%22Blennow+K%22">Blennow K</searchLink>; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Mölndal, S-43180, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, S- 43180, Sweden.; Paris Brain Institute, ICM, Pitié-Salpêtrière Hospital, Sorbonne University, Paris, 75013, France.; Neurodegenerative Disorder Research Center, Division of Life Sciences and Medicine, Department of Neurology, Institute on Aging and Brain Disorders, University of Science and Technology of China and First Affiliated Hospital of USTC, Hefei, 230026, P.R. China.<br /><searchLink fieldCode="AU" term="%22Zetterberg+H%22">Zetterberg H</searchLink>; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Mölndal, S-43180, Sweden.; Neurodegenerative Disorder Research Center, Division of Life Sciences and Medicine, Department of Neurology, Institute on Aging and Brain Disorders, University of Science and Technology of China and First Affiliated Hospital of USTC, Hefei, 230026, P.R. China.; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK.; UK Dementia Research Institute at UCL, London, WC1N 3BG, UK.; Hong Kong Center for Neurodegenerative Diseases, Clear Water Bay, Hong Kong, China.; Wisconsin Alzheimer's Disease Research Center, School of Medicine and Public Health, University of Wisconsin, University of Wisconsin-Madison, Madison, WI, 53792, USA.<br /><searchLink fieldCode="AU" term="%22Nitsch+RM%22">Nitsch RM</searchLink>; Institute for Regenerative Medicine, University of Zurich, Wagistrasse 12, Schlieren, 8952, Switzerland.; Neurimmune AG, Zurich, 8952, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hock+C%22">Hock C</searchLink>; Institute for Regenerative Medicine, University of Zurich, Wagistrasse 12, Schlieren, 8952, Switzerland.; Neurimmune AG, Zurich, 8952, Switzerland.; Center for Prevention and Dementia Therapy, University of Zurich, Zurich, 8952, Switzerland.<br /><searchLink fieldCode="AU" term="%22Treyer+V%22">Treyer V</searchLink>; Institute for Regenerative Medicine, University of Zurich, Wagistrasse 12, Schlieren, 8952, Switzerland.; Department of Nuclear Medicine, University Hospital of Zurich, University of Zurich, Zurich, 8091, Switzerland.; Center for Prevention and Dementia Therapy, University of Zurich, Zurich, 8952, Switzerland.<br /><searchLink fieldCode="AU" term="%22Gietl+A%22">Gietl A</searchLink>; Institute for Regenerative Medicine, University of Zurich, Wagistrasse 12, Schlieren, 8952, Switzerland.; Center for Prevention and Dementia Therapy, University of Zurich, Zurich, 8952, Switzerland.; Department of Geriatric Psychiatry, Psychiatric Hospital Zurich, Zurich, 8008, Switzerland. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101511643%22">Alzheimer's research & therapy</searchLink> [Alzheimers Res Ther] 2026 Mar 30; Vol. 18 (1). <i>Date of Electronic Publication: </i>2026 Mar 30. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central+Ltd%22">BioMed Central Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101511643 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1758-9193 (Electronic) <i>NLM ISO Abbreviation: </i>Alzheimers Res Ther <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41906163 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1186/s13195-026-02038-z Languages: – Code: eng Text: English Titles: – TitleFull: Independent and interactive contributions of white matter hyperintensities and Alzheimer's disease imaging and plasma biomarkers to cognitive decline in older adults without dementia. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Bachmann D – PersonEntity: Name: NameFull: Gericke C – PersonEntity: Name: NameFull: Wybitul M – PersonEntity: Name: NameFull: Saake A – PersonEntity: Name: NameFull: Studer S – PersonEntity: Name: NameFull: Rauen K – PersonEntity: Name: NameFull: Gruber E – PersonEntity: Name: NameFull: Buchmann A – PersonEntity: Name: NameFull: Hüllner M – PersonEntity: Name: NameFull: Blennow K – PersonEntity: Name: NameFull: Zetterberg H – PersonEntity: Name: NameFull: Nitsch RM – PersonEntity: Name: NameFull: Hock C – PersonEntity: Name: NameFull: Treyer V – PersonEntity: Name: NameFull: Gietl A IsPartOfRelationships: – BibEntity: Dates: – D: 30 M: 03 Text: 2026 Mar 30 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1758-9193 Numbering: – Type: volume Value: 18 – Type: issue Value: 1 Titles: – TitleFull: Alzheimer's research & therapy Type: main |
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