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Dietary fiber reduces mortality from secondary sepsis in a murine model of Clostridioides difficile infection.

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Title: Dietary fiber reduces mortality from secondary sepsis in a murine model of Clostridioides difficile infection.
Authors: Apgar M; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Wall ES; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Midura-Kiela M; University of Arizona, Department of Pediatrics, 1501 N. Campbell Ave, Tucson, AZ 85724, USA., Neff CP; University of Colorado, Anschutz, Aurora, CO 80045, USA., Orlicky DJ; Department of Pathology, University of Colorado School of Medicine, Aurora, CO 80045, USA., Lyon LM; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Bernardazzi C; Department of Pediatrics, University of Arizona Health Sciences, Tucson, AZ 85724, USA., Martin CG; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Gordon OM; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.; Center for Cancer and Blood Disorders, Children's Hospital of Colorado, Aurora, CO 80045, USA., Jimenez-Espinoza I; University of Arizona, Department of Pediatrics, 1501 N. Campbell Ave, Tucson, AZ 85724, USA., Flynn JK; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Lozupone CA; University of Colorado, Anschutz, Aurora, CO 80045, USA., Hazleton KZ; Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital Los Angeles, Los Angeles, CA 90027, USA.
Source: IScience [iScience] 2026 Mar 06; Vol. 29 (4), pp. 115258. Date of Electronic Publication: 2026 Mar 06 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE
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  Data: Dietary fiber reduces mortality from secondary sepsis in a murine model of Clostridioides difficile infection.
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  Data: <searchLink fieldCode="AU" term="%22Apgar+M%22">Apgar M</searchLink>; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.<br /><searchLink fieldCode="AU" term="%22Wall+ES%22">Wall ES</searchLink>; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.<br /><searchLink fieldCode="AU" term="%22Midura-Kiela+M%22">Midura-Kiela M</searchLink>; University of Arizona, Department of Pediatrics, 1501 N. Campbell Ave, Tucson, AZ 85724, USA.<br /><searchLink fieldCode="AU" term="%22Neff+CP%22">Neff CP</searchLink>; University of Colorado, Anschutz, Aurora, CO 80045, USA.<br /><searchLink fieldCode="AU" term="%22Orlicky+DJ%22">Orlicky DJ</searchLink>; Department of Pathology, University of Colorado School of Medicine, Aurora, CO 80045, USA.<br /><searchLink fieldCode="AU" term="%22Lyon+LM%22">Lyon LM</searchLink>; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.<br /><searchLink fieldCode="AU" term="%22Bernardazzi+C%22">Bernardazzi C</searchLink>; Department of Pediatrics, University of Arizona Health Sciences, Tucson, AZ 85724, USA.<br /><searchLink fieldCode="AU" term="%22Martin+CG%22">Martin CG</searchLink>; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.<br /><searchLink fieldCode="AU" term="%22Gordon+OM%22">Gordon OM</searchLink>; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.; Center for Cancer and Blood Disorders, Children's Hospital of Colorado, Aurora, CO 80045, USA.<br /><searchLink fieldCode="AU" term="%22Jimenez-Espinoza+I%22">Jimenez-Espinoza I</searchLink>; University of Arizona, Department of Pediatrics, 1501 N. Campbell Ave, Tucson, AZ 85724, USA.<br /><searchLink fieldCode="AU" term="%22Flynn+JK%22">Flynn JK</searchLink>; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.<br /><searchLink fieldCode="AU" term="%22Lozupone+CA%22">Lozupone CA</searchLink>; University of Colorado, Anschutz, Aurora, CO 80045, USA.<br /><searchLink fieldCode="AU" term="%22Hazleton+KZ%22">Hazleton KZ</searchLink>; Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital Los Angeles, Los Angeles, CA 90027, USA.
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  Data: <searchLink fieldCode="JN" term="%22101724038%22">IScience</searchLink> [iScience] 2026 Mar 06; Vol. 29 (4), pp. 115258. <i>Date of Electronic Publication: </i>2026 Mar 06 (<i>Print Publication: </i>2026).
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