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Whole Metagenomic Profiling Identifies a Gut Microbial Signature for Chronic Pancreatitis via Machine Learning.

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Title: Whole Metagenomic Profiling Identifies a Gut Microbial Signature for Chronic Pancreatitis via Machine Learning.
Authors: Bartelli TF; Department of Genetics, University of Texas MD Anderson Cancer Center, Houston TX., Baydogan S; Department of Genetics, University of Texas MD Anderson Cancer Center, Houston TX., Sahin I; Department of Engineering, Texas Southern University, Houston, TX., Hoffman KL; Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, TX., Petrosino J; Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, TX., Blackburn KW; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX., Zhao J; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX., Wood A; Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX., Ayvaz T; Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, TX., Surathu A; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX., Cagigas MN; Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX., Barcenas EC; Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX., Mata T; Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX., Nguyen VK; Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX., Zulbaran-Rojas A; Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX., Li L; Department of Genetics, University of Texas MD Anderson Cancer Center, Houston TX., Faraoni EY; Department of Genetics, University of Texas MD Anderson Cancer Center, Houston TX., White JR; Resphera Biosciences, Baltimore, MD., Ajami N; University of Texas MD Anderson Cancer Center, Platform for Innovative Microbiome and Translational Research, Houston, TX., Li L; Department of Biostatistics, Division of Discovery Science, University of Texas MD Anderson Cancer Center, Houston, TX., Yadav D; Department of Medicine, Division of Gastroenterology, Hepatology, and Nutrition University of Pittsburgh School of Medicine, Pittsburgh, PA., Conwell DL; Department of Internal Medicine, University of Kentucky College of Medicine, Lexington, KY., Serrano J; Division of Digestive Diseases and Nutrition, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD., Pandol SJ; Department of Medicine, Cedars-Sinai Medical Center, Basic and Translational Pancreas Research, Los Angeles, CA., Fogel EL; Department of Medicine, Indiana University School of Medicine, Digestive and Liver Disorders, Indianapolis, IN., Van Den Eden SK; Kaiser Permanente Northern California, Division of Research, Pleasanton, CA., Vege SS; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN., Topazian MD; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN., Park WG; Department of Medicine, Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA., Hart PA; Division of Gastroenterology, Hepatology, and Nutrition, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, OH., Forsmark C; Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Florida, Gainesville, FL., Bellin MD; Clinical and Translational Science Institute, University of Minnesota, Minneapolis, MN., Maitra A; Division of Pathology/Lab Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX.; Sheikh Ahmed Bin Zayed Al Nahyan Center for Pancreatic Cancer Research, Houston, TX., Bhutani MS; Department of Gastroenterology, Hepatology and Nutrition, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX.; Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX., Kim M; Department of Genetics, University of Texas MD Anderson Cancer Center, Houston TX.; Department of Surgical Oncology, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX., Van Buren G 2nd; Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX., Fisher WE; Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX., McAllister F; Department of Genetics, University of Texas MD Anderson Cancer Center, Houston TX.; Department of Gastrointestinal Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX.; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Corporate Authors: on Behalf
Source: Pancreas [Pancreas] 2026 May-Jun 01; Vol. 55 (5), pp. e458-e468. Date of Electronic Publication: 2026 Mar 30.
Publication Type: Journal Article
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 8608542 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1536-4828 (Electronic) Linking ISSN: 08853177 NLM ISO Abbreviation: Pancreas Subsets: MEDLINE
Database: MEDLINE Ultimate
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Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Wood+A%22">Wood A</searchLink>; Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Ayvaz+T%22">Ayvaz T</searchLink>; Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Surathu+A%22">Surathu A</searchLink>; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Cagigas+MN%22">Cagigas MN</searchLink>; Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Barcenas+EC%22">Barcenas EC</searchLink>; Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Mata+T%22">Mata T</searchLink>; Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Nguyen+VK%22">Nguyen VK</searchLink>; 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Division of Pathology/Lab Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX.; Sheikh Ahmed Bin Zayed Al Nahyan Center for Pancreatic Cancer Research, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Bhutani+MS%22">Bhutani MS</searchLink>; Department of Gastroenterology, Hepatology and Nutrition, Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX.; Department of Radiation Oncology, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Kim+M%22">Kim M</searchLink>; Department of Genetics, University of Texas MD Anderson Cancer Center, Houston TX.; Department of Surgical Oncology, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Van+Buren+G+2nd%22">Van Buren G 2nd</searchLink>; Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Fisher+WE%22">Fisher WE</searchLink>; 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