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Early vs Delayed Extubation After Thrombectomy for Acute Ischemic Stroke: The EDESTROKE Randomized Clinical Trial.

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Title: Early vs Delayed Extubation After Thrombectomy for Acute Ischemic Stroke: The EDESTROKE Randomized Clinical Trial.
Authors: Taboada M; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain., Estany-Gestal A; Research Methodology Unit, Fundación Instituto de Investigaciones Sanitarias (FIDIS), Santiago, Spain., Fernández J; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain., Dos Santos L; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain., Barreiro L; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain., Williams K; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain., Cardalda-Serantes B; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain., López C; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain., Méndez M; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain., Rodríguez-Yáñez M; Department of Neurology, University Clinical Hospital of Santiago, Spain., Otero P; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain., Naveira A; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain., Caruezo V; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain., Veiras S; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain., San Luis E; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain., Diaz-Vieito M; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain., Arias-Rivas S; Department of Neurology, University Clinical Hospital of Santiago, Spain., Santamaría-Cadavid M; Department of Neurology, University Clinical Hospital of Santiago, Spain., Rodríguez-Castro E; Department of Neurology, University Clinical Hospital of Santiago, Spain., Mosquera A; Department of Neuroradiology, University Clinical Hospital of Santiago, Spain., Castiñeiras JA; Department of Neuroradiology, University Clinical Hospital of Santiago, Spain., Vázquez F; Department of Neuroradiology, University Clinical Hospital of Santiago, Spain., Blanco M; Department of Neuroradiology, University Clinical Hospital of Santiago, Spain., Taboada JL; Department of Neuroradiology, University Clinical Hospital of Santiago, Spain., Muniategui I; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain., Ferreiroa E; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain., Cariñena A; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain., Tubio A; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain., Campaña O; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain., Selas S; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain., Aneiros F; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain., Martínez A; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain., Eiras M; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain., Costa J; Department of Neuroradiology, University Clinical Hospital of Santiago, Spain., Prieto JM; Department of Neurology, University Clinical Hospital of Santiago, Spain., Álvarez J; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain., Seoane-Pillado T; Preventive Medicine and Public Health Unit, department of Health Sciences, University of A Coruña-INIBIC, A Coruña, Spain.
Source: JAMA neurology [JAMA Neurol] 2026 May 01; Vol. 83 (5), pp. 481-489.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101589536 Publication Model: Print Cited Medium: Internet ISSN: 2168-6157 (Electronic) Linking ISSN: 21686149 NLM ISO Abbreviation: JAMA Neurol Subsets: MEDLINE
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  Data: Early vs Delayed Extubation After Thrombectomy for Acute Ischemic Stroke: The EDESTROKE Randomized Clinical Trial.
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  Data: <searchLink fieldCode="AU" term="%22Taboada+M%22">Taboada M</searchLink>; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Estany-Gestal+A%22">Estany-Gestal A</searchLink>; Research Methodology Unit, Fundación Instituto de Investigaciones Sanitarias (FIDIS), Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Fernández+J%22">Fernández J</searchLink>; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Dos+Santos+L%22">Dos Santos L</searchLink>; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Barreiro+L%22">Barreiro L</searchLink>; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Williams+K%22">Williams K</searchLink>; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Cardalda-Serantes+B%22">Cardalda-Serantes B</searchLink>; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22López+C%22">López C</searchLink>; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Méndez+M%22">Méndez M</searchLink>; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Rodríguez-Yáñez+M%22">Rodríguez-Yáñez M</searchLink>; Department of Neurology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Otero+P%22">Otero P</searchLink>; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Naveira+A%22">Naveira A</searchLink>; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Caruezo+V%22">Caruezo V</searchLink>; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Veiras+S%22">Veiras S</searchLink>; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22San+Luis+E%22">San Luis E</searchLink>; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Diaz-Vieito+M%22">Diaz-Vieito M</searchLink>; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Arias-Rivas+S%22">Arias-Rivas S</searchLink>; Department of Neurology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Santamaría-Cadavid+M%22">Santamaría-Cadavid M</searchLink>; Department of Neurology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Rodríguez-Castro+E%22">Rodríguez-Castro E</searchLink>; Department of Neurology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Mosquera+A%22">Mosquera A</searchLink>; Department of Neuroradiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Castiñeiras+JA%22">Castiñeiras JA</searchLink>; Department of Neuroradiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Vázquez+F%22">Vázquez F</searchLink>; Department of Neuroradiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Blanco+M%22">Blanco M</searchLink>; Department of Neuroradiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Taboada+JL%22">Taboada JL</searchLink>; Department of Neuroradiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Muniategui+I%22">Muniategui I</searchLink>; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Ferreiroa+E%22">Ferreiroa E</searchLink>; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Cariñena+A%22">Cariñena A</searchLink>; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Tubio+A%22">Tubio A</searchLink>; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Campaña+O%22">Campaña O</searchLink>; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Selas+S%22">Selas S</searchLink>; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Aneiros+F%22">Aneiros F</searchLink>; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Martínez+A%22">Martínez A</searchLink>; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Eiras+M%22">Eiras M</searchLink>; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Costa+J%22">Costa J</searchLink>; Department of Neuroradiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Prieto+JM%22">Prieto JM</searchLink>; Department of Neurology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Álvarez+J%22">Álvarez J</searchLink>; Department of Anesthesiology, University Clinical Hospital of Santiago, Spain.<br /><searchLink fieldCode="AU" term="%22Seoane-Pillado+T%22">Seoane-Pillado T</searchLink>; Preventive Medicine and Public Health Unit, department of Health Sciences, University of A Coruña-INIBIC, A Coruña, Spain.
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