Venetoclax combinations in untreated CLL: 5-year results and patient-reported outcomes analysis of the CLL13/GAIA trial.

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Title: Venetoclax combinations in untreated CLL: 5-year results and patient-reported outcomes analysis of the CLL13/GAIA trial.
Authors: Fürstenau M; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, German CLL Study Group, University of Cologne, Cologne, Germany., Niemann CU; Department of Hematology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Robrecht S; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, German CLL Study Group, University of Cologne, Cologne, Germany., Rotbain EC; Department of Hematology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Eurelings L; Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, The Netherlands., Giza A; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, German CLL Study Group, University of Cologne, Cologne, Germany., von Tresckow J; Department of Hematology, Oncology and Palliative Care, Katholisches Klinikum Bochum, Ruhr University Bochum, Bochum, Germany., Zhang C; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, German CLL Study Group, University of Cologne, Cologne, Germany., Gregor M; Division of Hematology, Cantonal Hospital of Lucerne, Lucerne, Switzerland., Thornton P; Department of Haematology, Beaumont Hospital, Royal College of Surgeons in Ireland, Cancer Trials Ireland, Dublin, Ireland., Staber PB; Department of Internal Medicine 1 (Oncology, Hematology, Clinical Immunology, and Rheumatology), Saarland University Medical School, Homburg, Germany., Tadmor T; Hematology Unit, Bnai-Zion Medical Center, and The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel., Lindström V; Comprehensive Cancer Center, Department of Hematology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Juliusson G; Department of Hematology, Skåne University Hospital, Lund, Sweden., Janssens A; Department of Oncology, Universitaire Ziekenhuizen Leuven, Leuven, Belgium., da Cunha-Bang C; Department of Hematology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Schneider C; Division of Chronic Lymphocytic Leukemia, Department of Internal Medicine III, University of Ulm, Ulm, Germany., Herishanu Y; Faculty of Medicine, Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel., O'Shea D; Department of Hematology, Cork University Hospital, Wilton, Ireland., Baumann M; Department of Hematology, Kantonsspital St. Gallen, St. Gallen, Switzerland., Widmer A; Department of Medical Oncology and Haematology, Universitätsspital Zürich, Zürich, Switzerland., Nösslinger T; 3rd Medical Department for Hematology and Oncology, Hanusch Krankenhaus, Vienna, Austria., Poulsen CB; Department of Hematology, Zealand University Hospital, Roskilde, Denmark., Frederiksen H; Department of Hematology, Odense University Hospital, Odense, Denmark., Lotfi K; Department of Hematology, Linköping University Hospital, Linköping, Sweden., Ranti J; Department of Hematology, Turku University Central Hospital, Turku, Finland., Enggaard L; Department of Hematology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Velders G; Department of Hematology, Gelderse Vallei Hospital, Ede, The Netherlands., Vekemans MC; Department of Hematology, Cliniques Universitaires Saint-Luc, Brussels, Belgium., de Heer K; Department of Internal Medicine, Flevoziekenhuis, Almere, The Netherlands., Snijders TF; Department of Hematology, Medisch Spectrum Twente, Enschede, The Netherlands., Siemes C; Department of Hematology, Deventer Hospital, Deventer, The Netherlands., Wendtner CM; Medizinische Klinik III, Ludwig-Maximilians-Universität, Munich, Germany., Knauf W; Centrum für Hämatologie und Onkologie Bethanien, Frankfurt am Main, Germany., Kroeber A; Schwerpunktpraxis und Tagesklinik für Hämatologie und Onkologie, Regensburg, Germany., Zahn MO; MVZ Onkologische Kooperation Harz, Goslar, Germany., Illmer T; Gemeinschaftspraxis Hämatologie-Onkologie, Dresden, Germany., Schöttker B; Hämatologisch-Onkologische Schwerpunktpraxis Würzburg, Würzburg, Germany., Simon F; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, German CLL Study Group, University of Cologne, Cologne, Germany., Fink A; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, German CLL Study Group, University of Cologne, Cologne, Germany., Fischer K; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, German CLL Study Group, University of Cologne, Cologne, Germany., D'Brot R; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, German CLL Study Group, University of Cologne, Cologne, Germany., Holmes E; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, German CLL Study Group, University of Cologne, Cologne, Germany., Kreuzer KA; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, German CLL Study Group, University of Cologne, Cologne, Germany., Ritgen M; Department of Internal Medicine II, University Medical Center Schleswig-Holstein, Kiel, Germany., Brüggemann M; Department of Internal Medicine II, University Medical Center Schleswig-Holstein, Kiel, Germany., Tausch E; Division of Chronic Lymphocytic Leukemia, Department of Internal Medicine III, University of Ulm, Ulm, Germany., Stilgenbauer S; Division of Chronic Lymphocytic Leukemia, Department of Internal Medicine III, University of Ulm, Ulm, Germany., Levin MD; Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, The Netherlands., Hallek M; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, German CLL Study Group, University of Cologne, Cologne, Germany., Kater AP; Department of Hematology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands., Eichhorst B; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, German CLL Study Group, University of Cologne, Cologne, Germany.
Source: Blood [Blood] 2026 Jun 18; Vol. 147 (25), pp. 3025-3038.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III; Multicenter Study
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Venetoclax combinations in untreated CLL: 5-year results and patient-reported outcomes analysis of the CLL13/GAIA trial.
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  Data: <searchLink fieldCode="AU" term="%22Fürstenau+M%22">Fürstenau M</searchLink>; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, German CLL Study Group, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Niemann+CU%22">Niemann CU</searchLink>; Department of Hematology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Robrecht+S%22">Robrecht S</searchLink>; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, German CLL Study Group, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Rotbain+EC%22">Rotbain EC</searchLink>; Department of Hematology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Eurelings+L%22">Eurelings L</searchLink>; Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Giza+A%22">Giza A</searchLink>; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, German CLL Study Group, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22von+Tresckow+J%22">von Tresckow J</searchLink>; Department of Hematology, Oncology and Palliative Care, Katholisches Klinikum Bochum, Ruhr University Bochum, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, German CLL Study Group, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Gregor+M%22">Gregor M</searchLink>; Division of Hematology, Cantonal Hospital of Lucerne, Lucerne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Thornton+P%22">Thornton P</searchLink>; Department of Haematology, Beaumont Hospital, Royal College of Surgeons in Ireland, Cancer Trials Ireland, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Staber+PB%22">Staber PB</searchLink>; Department of Internal Medicine 1 (Oncology, Hematology, Clinical Immunology, and Rheumatology), Saarland University Medical School, Homburg, Germany.<br /><searchLink fieldCode="AU" term="%22Tadmor+T%22">Tadmor T</searchLink>; Hematology Unit, Bnai-Zion Medical Center, and The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel.<br /><searchLink fieldCode="AU" term="%22Lindström+V%22">Lindström V</searchLink>; Comprehensive Cancer Center, Department of Hematology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Juliusson+G%22">Juliusson G</searchLink>; Department of Hematology, Skåne University Hospital, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Janssens+A%22">Janssens A</searchLink>; Department of Oncology, Universitaire Ziekenhuizen Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22da+Cunha-Bang+C%22">da Cunha-Bang C</searchLink>; Department of Hematology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Schneider+C%22">Schneider C</searchLink>; Division of Chronic Lymphocytic Leukemia, Department of Internal Medicine III, University of Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Herishanu+Y%22">Herishanu Y</searchLink>; Faculty of Medicine, Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22O'Shea+D%22">O'Shea D</searchLink>; Department of Hematology, Cork University Hospital, Wilton, Ireland.<br /><searchLink fieldCode="AU" term="%22Baumann+M%22">Baumann M</searchLink>; Department of Hematology, Kantonsspital St. Gallen, St. Gallen, Switzerland.<br /><searchLink fieldCode="AU" term="%22Widmer+A%22">Widmer A</searchLink>; Department of Medical Oncology and Haematology, Universitätsspital Zürich, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Nösslinger+T%22">Nösslinger T</searchLink>; 3rd Medical Department for Hematology and Oncology, Hanusch Krankenhaus, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Poulsen+CB%22">Poulsen CB</searchLink>; Department of Hematology, Zealand University Hospital, Roskilde, Denmark.<br /><searchLink fieldCode="AU" term="%22Frederiksen+H%22">Frederiksen H</searchLink>; Department of Hematology, Odense University Hospital, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Lotfi+K%22">Lotfi K</searchLink>; Department of Hematology, Linköping University Hospital, Linköping, Sweden.<br /><searchLink fieldCode="AU" term="%22Ranti+J%22">Ranti J</searchLink>; Department of Hematology, Turku University Central Hospital, Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Enggaard+L%22">Enggaard L</searchLink>; Department of Hematology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Velders+G%22">Velders G</searchLink>; Department of Hematology, Gelderse Vallei Hospital, Ede, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Vekemans+MC%22">Vekemans MC</searchLink>; Department of Hematology, Cliniques Universitaires Saint-Luc, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22de+Heer+K%22">de Heer K</searchLink>; Department of Internal Medicine, Flevoziekenhuis, Almere, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Snijders+TF%22">Snijders TF</searchLink>; Department of Hematology, Medisch Spectrum Twente, Enschede, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Siemes+C%22">Siemes C</searchLink>; Department of Hematology, Deventer Hospital, Deventer, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Wendtner+CM%22">Wendtner CM</searchLink>; Medizinische Klinik III, Ludwig-Maximilians-Universität, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Knauf+W%22">Knauf W</searchLink>; Centrum für Hämatologie und Onkologie Bethanien, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Kroeber+A%22">Kroeber A</searchLink>; Schwerpunktpraxis und Tagesklinik für Hämatologie und Onkologie, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Zahn+MO%22">Zahn MO</searchLink>; MVZ Onkologische Kooperation Harz, Goslar, Germany.<br /><searchLink fieldCode="AU" term="%22Illmer+T%22">Illmer T</searchLink>; Gemeinschaftspraxis Hämatologie-Onkologie, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Schöttker+B%22">Schöttker B</searchLink>; Hämatologisch-Onkologische Schwerpunktpraxis Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Simon+F%22">Simon F</searchLink>; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, German CLL Study Group, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Fink+A%22">Fink A</searchLink>; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, German CLL Study Group, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Fischer+K%22">Fischer K</searchLink>; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, German CLL Study Group, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22D'Brot+R%22">D'Brot R</searchLink>; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, German CLL Study Group, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Holmes+E%22">Holmes E</searchLink>; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, German CLL Study Group, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Kreuzer+KA%22">Kreuzer KA</searchLink>; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, German CLL Study Group, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Ritgen+M%22">Ritgen M</searchLink>; Department of Internal Medicine II, University Medical Center Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Brüggemann+M%22">Brüggemann M</searchLink>; Department of Internal Medicine II, University Medical Center Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Tausch+E%22">Tausch E</searchLink>; Division of Chronic Lymphocytic Leukemia, Department of Internal Medicine III, University of Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Stilgenbauer+S%22">Stilgenbauer S</searchLink>; Division of Chronic Lymphocytic Leukemia, Department of Internal Medicine III, University of Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Levin+MD%22">Levin MD</searchLink>; Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Hallek+M%22">Hallek M</searchLink>; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, German CLL Study Group, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Kater+AP%22">Kater AP</searchLink>; Department of Hematology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Eichhorst+B%22">Eichhorst B</searchLink>; Faculty of Medicine and University Hospital Cologne, Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, German CLL Study Group, University of Cologne, Cologne, Germany.
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    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 18
              M: 06
              Text: 2026 Jun 18
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1528-0020
          Numbering:
            – Type: volume
              Value: 147
            – Type: issue
              Value: 25
          Titles:
            – TitleFull: Blood
              Type: main
ResultId 1