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Humic substances enhance the anti-cancer efficacy of standard therapies.

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Title: Humic substances enhance the anti-cancer efficacy of standard therapies.
Authors: Bianca P; Department of Health Promotion Sciences, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy.; Azienda Ospedaliera Universitaria Policlinico 'Paolo Giaccone' (AOUP), Palermo, Italy., Modica C; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy., Verrillo M; Department of Agricultural Sciences, University of Naples Federico II, Naples, Italy., Lo Iacono M; Department of Health Promotion Sciences, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy., Mangiapane LR; Department of Health Promotion Sciences, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy., Shams K; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy., Roozafzay N; Department of Health Promotion Sciences, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy., Pantina VD; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy., Bozzari G; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy., Di Bella S; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy., Orilio F; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy., D'Accardo C; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy., Porcelli G; Department of Health Promotion Sciences, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy., Drago R; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy., Verona F; Azienda Ospedaliera Universitaria Policlinico 'Paolo Giaccone' (AOUP), Palermo, Italy.; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy., Brancaccio RN; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy., Turdo A; Department of Health Promotion Sciences, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy., Gaggianesi M; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy., Di Franco S; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy., Cozzolino V; Department of Agricultural Sciences, University of Naples Federico II, Naples, Italy., Spaccini R; Department of Agricultural Sciences, University of Naples Federico II, Naples, Italy., Todaro M; Department of Health Promotion Sciences, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy.; Azienda Ospedaliera Universitaria Policlinico 'Paolo Giaccone' (AOUP), Palermo, Italy., Stassi G; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy. giorgio.stassi@unipa.it.; IRCCS SDN, Naples, Italy. giorgio.stassi@unipa.it.
Source: Cell death discovery [Cell Death Discov] 2026 Mar 31; Vol. 12 (1). Date of Electronic Publication: 2026 Mar 31.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Humic substances enhance the anti-cancer efficacy of standard therapies.
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  Data: <searchLink fieldCode="AU" term="%22Bianca+P%22">Bianca P</searchLink>; Department of Health Promotion Sciences, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy.; Azienda Ospedaliera Universitaria Policlinico 'Paolo Giaccone' (AOUP), Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Modica+C%22">Modica C</searchLink>; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Verrillo+M%22">Verrillo M</searchLink>; Department of Agricultural Sciences, University of Naples Federico II, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Lo+Iacono+M%22">Lo Iacono M</searchLink>; Department of Health Promotion Sciences, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Mangiapane+LR%22">Mangiapane LR</searchLink>; Department of Health Promotion Sciences, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Shams+K%22">Shams K</searchLink>; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Roozafzay+N%22">Roozafzay N</searchLink>; Department of Health Promotion Sciences, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Pantina+VD%22">Pantina VD</searchLink>; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Bozzari+G%22">Bozzari G</searchLink>; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Bella+S%22">Di Bella S</searchLink>; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Orilio+F%22">Orilio F</searchLink>; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22D'Accardo+C%22">D'Accardo C</searchLink>; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Porcelli+G%22">Porcelli G</searchLink>; Department of Health Promotion Sciences, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Drago+R%22">Drago R</searchLink>; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Verona+F%22">Verona F</searchLink>; Azienda Ospedaliera Universitaria Policlinico 'Paolo Giaccone' (AOUP), Palermo, Italy.; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Brancaccio+RN%22">Brancaccio RN</searchLink>; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Turdo+A%22">Turdo A</searchLink>; Department of Health Promotion Sciences, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Gaggianesi+M%22">Gaggianesi M</searchLink>; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Franco+S%22">Di Franco S</searchLink>; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Cozzolino+V%22">Cozzolino V</searchLink>; Department of Agricultural Sciences, University of Naples Federico II, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Spaccini+R%22">Spaccini R</searchLink>; Department of Agricultural Sciences, University of Naples Federico II, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Todaro+M%22">Todaro M</searchLink>; Department of Health Promotion Sciences, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy.; Azienda Ospedaliera Universitaria Policlinico 'Paolo Giaccone' (AOUP), Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Stassi+G%22">Stassi G</searchLink>; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy. giorgio.stassi@unipa.it.; IRCCS SDN, Naples, Italy. giorgio.stassi@unipa.it.
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  Data: <searchLink fieldCode="JN" term="%22101665035%22">Cell death discovery</searchLink> [Cell Death Discov] 2026 Mar 31; Vol. 12 (1). <i>Date of Electronic Publication: </i>2026 Mar 31.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101665035 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2058-7716 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220587716%22">20587716 </searchLink><i>NLM ISO Abbreviation: </i>Cell Death Discov <i>Subsets: </i>PubMed not MEDLINE
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