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Knockdown of Ddx3x in mPFC induces autistic-like phenotype in mice via altered synaptic plasticity.

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Title: Knockdown of Ddx3x in mPFC induces autistic-like phenotype in mice via altered synaptic plasticity.
Authors: Zhuang H; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China., Cao X; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China., Tang X; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China., Liang Z; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China., Wang H; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China., Liu Q; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China.; Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, 518055, P. R. China., Yan X; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China., Lin X; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China., Su X; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China., Wang M; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China., Huang Y; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China., Lu D; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China., Wang Y; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China., Chen H; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China., Shen L; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China. slm@szu.edu.cn.; Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, 518055, P. R. China. slm@szu.edu.cn.
Source: Translational psychiatry [Transl Psychiatry] 2026 Mar 30; Vol. 16 (1). Date of Electronic Publication: 2026 Mar 30.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Knockdown of Ddx3x in mPFC induces autistic-like phenotype in mice via altered synaptic plasticity.
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  Data: <searchLink fieldCode="AU" term="%22Zhuang+H%22">Zhuang H</searchLink>; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China.<br /><searchLink fieldCode="AU" term="%22Cao+X%22">Cao X</searchLink>; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China.<br /><searchLink fieldCode="AU" term="%22Tang+X%22">Tang X</searchLink>; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China.<br /><searchLink fieldCode="AU" term="%22Liang+Z%22">Liang Z</searchLink>; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China.<br /><searchLink fieldCode="AU" term="%22Liu+Q%22">Liu Q</searchLink>; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China.; Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, 518055, P. R. China.<br /><searchLink fieldCode="AU" term="%22Yan+X%22">Yan X</searchLink>; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China.<br /><searchLink fieldCode="AU" term="%22Lin+X%22">Lin X</searchLink>; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China.<br /><searchLink fieldCode="AU" term="%22Su+X%22">Su X</searchLink>; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China.<br /><searchLink fieldCode="AU" term="%22Wang+M%22">Wang M</searchLink>; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China.<br /><searchLink fieldCode="AU" term="%22Lu+D%22">Lu D</searchLink>; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China.<br /><searchLink fieldCode="AU" term="%22Chen+H%22">Chen H</searchLink>; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China.<br /><searchLink fieldCode="AU" term="%22Shen+L%22">Shen L</searchLink>; College of Life Science and Oceanography, Shenzhen University, Shenzhen, 518071, P. R. China. slm@szu.edu.cn.; Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, 518055, P. R. China. slm@szu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101562664%22">Translational psychiatry</searchLink> [Transl Psychiatry] 2026 Mar 30; Vol. 16 (1). <i>Date of Electronic Publication: </i>2026 Mar 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101562664 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2158-3188 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221583188%22">21583188 </searchLink><i>NLM ISO Abbreviation: </i>Transl Psychiatry <i>Subsets: </i>MEDLINE
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              Text: 2026 Mar 30
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