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Intracellular and dual-site inhibition of a bitter taste GPCR.

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Title: Intracellular and dual-site inhibition of a bitter taste GPCR.
Authors: Dallal N; The Robert H. Smith Faculty of Agriculture, Food and Environment, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University, Rehovot, Israel., Daniel Paz G; The Robert H. Smith Faculty of Agriculture, Food and Environment, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University, Rehovot, Israel., Nir-Marom N; The Robert H. Smith Faculty of Agriculture, Food and Environment, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University, Rehovot, Israel., Keselman Y; The Robert H. Smith Faculty of Agriculture, Food and Environment, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University, Rehovot, Israel., Eyal S; The Robert H. Smith Faculty of Agriculture, Food and Environment, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University, Rehovot, Israel., Ziaikin E; The Robert H. Smith Faculty of Agriculture, Food and Environment, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University, Rehovot, Israel., Rainish A; The Robert H. Smith Faculty of Agriculture, Food and Environment, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University, Rehovot, Israel., Hoare SRJ; Pharmechanics LLC, 14 Sunnyside Drive South, Owego, NY, 13827, USA., Peri L; The Robert H. Smith Faculty of Agriculture, Food and Environment, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University, Rehovot, Israel., Malach E; The Robert H. Smith Faculty of Agriculture, Food and Environment, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University, Rehovot, Israel., Niv MY; The Robert H. Smith Faculty of Agriculture, Food and Environment, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University, Rehovot, Israel. masha.niv@mail.huji.ac.il.
Source: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2026 Mar 30; Vol. 83 (1). Date of Electronic Publication: 2026 Mar 30.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Intracellular and dual-site inhibition of a bitter taste GPCR.
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  Data: <searchLink fieldCode="AU" term="%22Dallal+N%22">Dallal N</searchLink>; The Robert H. Smith Faculty of Agriculture, Food and Environment, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Daniel+Paz+G%22">Daniel Paz G</searchLink>; The Robert H. Smith Faculty of Agriculture, Food and Environment, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Nir-Marom+N%22">Nir-Marom N</searchLink>; The Robert H. Smith Faculty of Agriculture, Food and Environment, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Keselman+Y%22">Keselman Y</searchLink>; The Robert H. Smith Faculty of Agriculture, Food and Environment, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Eyal+S%22">Eyal S</searchLink>; The Robert H. Smith Faculty of Agriculture, Food and Environment, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Ziaikin+E%22">Ziaikin E</searchLink>; The Robert H. Smith Faculty of Agriculture, Food and Environment, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Rainish+A%22">Rainish A</searchLink>; The Robert H. Smith Faculty of Agriculture, Food and Environment, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Hoare+SRJ%22">Hoare SRJ</searchLink>; Pharmechanics LLC, 14 Sunnyside Drive South, Owego, NY, 13827, USA.<br /><searchLink fieldCode="AU" term="%22Peri+L%22">Peri L</searchLink>; The Robert H. Smith Faculty of Agriculture, Food and Environment, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Malach+E%22">Malach E</searchLink>; The Robert H. Smith Faculty of Agriculture, Food and Environment, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Niv+MY%22">Niv MY</searchLink>; The Robert H. Smith Faculty of Agriculture, Food and Environment, Institute of Biochemistry, Food Science and Nutrition, The Hebrew University, Rehovot, Israel. masha.niv@mail.huji.ac.il.
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  Data: <searchLink fieldCode="JN" term="%229705402%22">Cellular and molecular life sciences : CMLS</searchLink> [Cell Mol Life Sci] 2026 Mar 30; Vol. 83 (1). <i>Date of Electronic Publication: </i>2026 Mar 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>9705402 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1420-9071 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221420682X%22">1420682X </searchLink><i>NLM ISO Abbreviation: </i>Cell Mol Life Sci <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s00018-026-06192-3
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              Text: 2026 Mar 30
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