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Decoding sex and gender effects on health: evidence from a nationwide cohort.

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Title: Decoding sex and gender effects on health: evidence from a nationwide cohort.
Authors: Gebhard CE; Intensive Care Unit, Department of Acute Medicine, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland. evacaroline.gebhard@usb.ch.; University of Basel, Basel, Switzerland. evacaroline.gebhard@usb.ch., Gysi B; Intensive Care Unit, Department of Acute Medicine, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland., Gebert P; Institute of Biometry and Clinical Epidemiology, Charité, Universitätsmedizin Berlin, Berlin, Germany., Mikail N; Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Center for Molecular Cardiology, University of Zurich, Schlieren, Switzerland., Liechti L; Clinic of Conservative and Preventive Dentistry, Center of Dental Medicine, University of Zurich, Zurich, Switzerland., Schmidlin PR; Clinic of Conservative and Preventive Dentistry, Center of Dental Medicine, University of Zurich, Zurich, Switzerland., Vinzens A; Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Center for Molecular Cardiology, University of Zurich, Schlieren, Switzerland., Haider A; Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Center for Molecular Cardiology, University of Zurich, Schlieren, Switzerland.; Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland., Bengs S; Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Center for Molecular Cardiology, University of Zurich, Schlieren, Switzerland., Treyer V; Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Buehler PK; Institute of Intensive Care, University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Institute of Intensive Care Medicine, Cantonal Hospital Winterthur, Winterthur, Switzerland., Schuepbach RA; Institute of Intensive Care, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Zinkernagel AS; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Brugger SD; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Patriki D; Department of Cardiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Wiggli B; Infectious Diseases and Hospital Epidemiology, Department of Internal Medicine, Cantonal Hospital of Baden, Baden, Switzerland., Beer JH; Center for Molecular Cardiology, University of Zurich, Schlieren, Switzerland.; Department of Internal Medicine, Cantonal Hospital of Baden, Baden, Switzerland.; University of Zurich, Zurich, Switzerland., Friedl A; Infectious Diseases and Hospital Epidemiology, Department of Internal Medicine, Cantonal Hospital of Baden, Baden, Switzerland., Twerenbold R; Department of Cardiology, University Hospital Basel, Basel, Switzerland.; Department of Cardiology and University Center of Cardiovascular Science, University Heart and Vascular Center Hamburg, Hamburg, Germany., Kuster GM; Department of Cardiology, University Hospital Basel, Basel, Switzerland.; Department of Biomedicine, University of Basel and University Hospital Basel, Basel, Switzerland., Schefold JC; Department of Intensive Care Medicine, Inselspital Bern University Hospital, University of Bern, Bern, Switzerland., Spinetti T; Department of Intensive Care Medicine, Inselspital Bern University Hospital, University of Bern, Bern, Switzerland., Wendel-Garcia PD; Institute of Intensive Care, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Hofmaenner DA; Institute of Intensive Care, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Scheier T; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Siegemund M; Intensive Care Unit, Department of Acute Medicine, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland.; University of Basel, Basel, Switzerland., Regitz-Zagrosek V; Charité, Universitätsmedizin Berlin, Berlin, Germany.; University of Zurich, Zurich, Switzerland., Gebhard C; Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Center for Molecular Cardiology, University of Zurich, Schlieren, Switzerland.; Department of Cardiology, Bern University Hospital Inselspital, University of Bern, Bern, Switzerland.
Source: Biology of sex differences [Biol Sex Differ] 2026 Mar 30; Vol. 17 (1). Date of Electronic Publication: 2026 Mar 30.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101548963 Publication Model: Electronic Cited Medium: Internet ISSN: 2042-6410 (Electronic) Linking ISSN: 20426410 NLM ISO Abbreviation: Biol Sex Differ Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Decoding sex and gender effects on health: evidence from a nationwide cohort.
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  Data: <searchLink fieldCode="AU" term="%22Gebhard+CE%22">Gebhard CE</searchLink>; Intensive Care Unit, Department of Acute Medicine, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland. evacaroline.gebhard@usb.ch.; University of Basel, Basel, Switzerland. evacaroline.gebhard@usb.ch.<br /><searchLink fieldCode="AU" term="%22Gysi+B%22">Gysi B</searchLink>; Intensive Care Unit, Department of Acute Medicine, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Gebert+P%22">Gebert P</searchLink>; Institute of Biometry and Clinical Epidemiology, Charité, Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Mikail+N%22">Mikail N</searchLink>; Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Center for Molecular Cardiology, University of Zurich, Schlieren, Switzerland.<br /><searchLink fieldCode="AU" term="%22Liechti+L%22">Liechti L</searchLink>; Clinic of Conservative and Preventive Dentistry, Center of Dental Medicine, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Schmidlin+PR%22">Schmidlin PR</searchLink>; Clinic of Conservative and Preventive Dentistry, Center of Dental Medicine, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Vinzens+A%22">Vinzens A</searchLink>; Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Center for Molecular Cardiology, University of Zurich, Schlieren, Switzerland.<br /><searchLink fieldCode="AU" term="%22Haider+A%22">Haider A</searchLink>; Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Center for Molecular Cardiology, University of Zurich, Schlieren, Switzerland.; Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bengs+S%22">Bengs S</searchLink>; Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Center for Molecular Cardiology, University of Zurich, Schlieren, Switzerland.<br /><searchLink fieldCode="AU" term="%22Treyer+V%22">Treyer V</searchLink>; Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Buehler+PK%22">Buehler PK</searchLink>; Institute of Intensive Care, University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Institute of Intensive Care Medicine, Cantonal Hospital Winterthur, Winterthur, Switzerland.<br /><searchLink fieldCode="AU" term="%22Schuepbach+RA%22">Schuepbach RA</searchLink>; Institute of Intensive Care, University Hospital Zurich, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Zinkernagel+AS%22">Zinkernagel AS</searchLink>; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Brugger+SD%22">Brugger SD</searchLink>; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Patriki+D%22">Patriki D</searchLink>; Department of Cardiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wiggli+B%22">Wiggli B</searchLink>; Infectious Diseases and Hospital Epidemiology, Department of Internal Medicine, Cantonal Hospital of Baden, Baden, Switzerland.<br /><searchLink fieldCode="AU" term="%22Beer+JH%22">Beer JH</searchLink>; Center for Molecular Cardiology, University of Zurich, Schlieren, Switzerland.; Department of Internal Medicine, Cantonal Hospital of Baden, Baden, Switzerland.; University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Friedl+A%22">Friedl A</searchLink>; Infectious Diseases and Hospital Epidemiology, Department of Internal Medicine, Cantonal Hospital of Baden, Baden, Switzerland.<br /><searchLink fieldCode="AU" term="%22Twerenbold+R%22">Twerenbold R</searchLink>; Department of Cardiology, University Hospital Basel, Basel, Switzerland.; Department of Cardiology and University Center of Cardiovascular Science, University Heart and Vascular Center Hamburg, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Kuster+GM%22">Kuster GM</searchLink>; Department of Cardiology, University Hospital Basel, Basel, Switzerland.; Department of Biomedicine, University of Basel and University Hospital Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Schefold+JC%22">Schefold JC</searchLink>; Department of Intensive Care Medicine, Inselspital Bern University Hospital, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Spinetti+T%22">Spinetti T</searchLink>; Department of Intensive Care Medicine, Inselspital Bern University Hospital, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wendel-Garcia+PD%22">Wendel-Garcia PD</searchLink>; Institute of Intensive Care, University Hospital Zurich, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hofmaenner+DA%22">Hofmaenner DA</searchLink>; Institute of Intensive Care, University Hospital Zurich, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Scheier+T%22">Scheier T</searchLink>; Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Siegemund+M%22">Siegemund M</searchLink>; Intensive Care Unit, Department of Acute Medicine, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland.; University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Regitz-Zagrosek+V%22">Regitz-Zagrosek V</searchLink>; Charité, Universitätsmedizin Berlin, Berlin, Germany.; University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Gebhard+C%22">Gebhard C</searchLink>; Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Center for Molecular Cardiology, University of Zurich, Schlieren, Switzerland.; Department of Cardiology, Bern University Hospital Inselspital, University of Bern, Bern, Switzerland.
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  Data: <searchLink fieldCode="JN" term="%22101548963%22">Biology of sex differences</searchLink> [Biol Sex Differ] 2026 Mar 30; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Mar 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101548963 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2042-6410 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220426410%22">20426410 </searchLink><i>NLM ISO Abbreviation: </i>Biol Sex Differ <i>Subsets: </i>MEDLINE
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