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MDA5 generates compact ribonucleoprotein complexes via ATP-dependent double-stranded RNA unwinding.

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Title: MDA5 generates compact ribonucleoprotein complexes via ATP-dependent double-stranded RNA unwinding.
Authors: Quack S; Department of Physics and Astronomy, and LaserLaB Amsterdam, Vrije Universiteit Amsterdam, De Boelelaan 1100, 1081 HZ Amsterdam, The Netherlands.; Junior Research Group 2, Interdisciplinary Center for Clinical Research, Friedrich-Alexander-University Erlangen-Nürnberg, Cauerstr. 3, 91058 Erlangen, Germany., Maity S; Moleculaire Biofysica, Zernike Instituut, Rijksuniversiteit Groningen, Nijenborgh 3, 9747 AG Groningen, The Netherlands., America PPB; Department of Physics and Astronomy, and LaserLaB Amsterdam, Vrije Universiteit Amsterdam, De Boelelaan 1100, 1081 HZ Amsterdam, The Netherlands., Klein M; Department of Physics and Astronomy, and LaserLaB Amsterdam, Vrije Universiteit Amsterdam, De Boelelaan 1100, 1081 HZ Amsterdam, The Netherlands., Herrero Del Valle A; Molecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology,Francis Crick Avenue, Trumpington, Cambridge CB2 0QH, United Kingdom.; Cambridge Institute of Therapeutic Immunology and Infectious Disease, Department of Medicine, University of Cambridge, Francis Crick Avenue, Trumpington, Cambridge CB2 0QH, United Kingdom., Singh R; Molecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology,Francis Crick Avenue, Trumpington, Cambridge CB2 0QH, United Kingdom.; Cambridge Institute of Therapeutic Immunology and Infectious Disease, Department of Medicine, University of Cambridge, Francis Crick Avenue, Trumpington, Cambridge CB2 0QH, United Kingdom., Joiner JD; Molecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology,Francis Crick Avenue, Trumpington, Cambridge CB2 0QH, United Kingdom.; Cambridge Institute of Therapeutic Immunology and Infectious Disease, Department of Medicine, University of Cambridge, Francis Crick Avenue, Trumpington, Cambridge CB2 0QH, United Kingdom., Rashid ZM; Department of Physics and Astronomy, and LaserLaB Amsterdam, Vrije Universiteit Amsterdam, De Boelelaan 1100, 1081 HZ Amsterdam, The Netherlands., Smitskamp Q; Department of Physics and Astronomy, and LaserLaB Amsterdam, Vrije Universiteit Amsterdam, De Boelelaan 1100, 1081 HZ Amsterdam, The Netherlands., Rivas P; Department of Physics and Astronomy, and LaserLaB Amsterdam, Vrije Universiteit Amsterdam, De Boelelaan 1100, 1081 HZ Amsterdam, The Netherlands., Papini FS; Junior Research Group 2, Interdisciplinary Center for Clinical Research, Friedrich-Alexander-University Erlangen-Nürnberg, Cauerstr. 3, 91058 Erlangen, Germany., Broedersz CP; Department of Physics and Astronomy, and LaserLaB Amsterdam, Vrije Universiteit Amsterdam, De Boelelaan 1100, 1081 HZ Amsterdam, The Netherlands., Roos WH; Moleculaire Biofysica, Zernike Instituut, Rijksuniversiteit Groningen, Nijenborgh 3, 9747 AG Groningen, The Netherlands., Modis Y; Molecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology,Francis Crick Avenue, Trumpington, Cambridge CB2 0QH, United Kingdom.; Cambridge Institute of Therapeutic Immunology and Infectious Disease, Department of Medicine, University of Cambridge, Francis Crick Avenue, Trumpington, Cambridge CB2 0QH, United Kingdom., Dulin D; Department of Physics and Astronomy, and LaserLaB Amsterdam, Vrije Universiteit Amsterdam, De Boelelaan 1100, 1081 HZ Amsterdam, The Netherlands.; Junior Research Group 2, Interdisciplinary Center for Clinical Research, Friedrich-Alexander-University Erlangen-Nürnberg, Cauerstr. 3, 91058 Erlangen, Germany.
Source: Nucleic acids research [Nucleic Acids Res] 2026 Mar 19; Vol. 54 (6).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
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  Data: MDA5 generates compact ribonucleoprotein complexes via ATP-dependent double-stranded RNA unwinding.
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  Data: <searchLink fieldCode="AU" term="%22Quack+S%22">Quack S</searchLink>; Department of Physics and Astronomy, and LaserLaB Amsterdam, Vrije Universiteit Amsterdam, De Boelelaan 1100, 1081 HZ Amsterdam, The Netherlands.; Junior Research Group 2, Interdisciplinary Center for Clinical Research, Friedrich-Alexander-University Erlangen-Nürnberg, Cauerstr. 3, 91058 Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Maity+S%22">Maity S</searchLink>; Moleculaire Biofysica, Zernike Instituut, Rijksuniversiteit Groningen, Nijenborgh 3, 9747 AG Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22America+PPB%22">America PPB</searchLink>; Department of Physics and Astronomy, and LaserLaB Amsterdam, Vrije Universiteit Amsterdam, De Boelelaan 1100, 1081 HZ Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Klein+M%22">Klein M</searchLink>; Department of Physics and Astronomy, and LaserLaB Amsterdam, Vrije Universiteit Amsterdam, De Boelelaan 1100, 1081 HZ Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Herrero+Del+Valle+A%22">Herrero Del Valle A</searchLink>; Molecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology,Francis Crick Avenue, Trumpington, Cambridge CB2 0QH, United Kingdom.; Cambridge Institute of Therapeutic Immunology and Infectious Disease, Department of Medicine, University of Cambridge, Francis Crick Avenue, Trumpington, Cambridge CB2 0QH, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Singh+R%22">Singh R</searchLink>; Molecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology,Francis Crick Avenue, Trumpington, Cambridge CB2 0QH, United Kingdom.; Cambridge Institute of Therapeutic Immunology and Infectious Disease, Department of Medicine, University of Cambridge, Francis Crick Avenue, Trumpington, Cambridge CB2 0QH, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Joiner+JD%22">Joiner JD</searchLink>; Molecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology,Francis Crick Avenue, Trumpington, Cambridge CB2 0QH, United Kingdom.; Cambridge Institute of Therapeutic Immunology and Infectious Disease, Department of Medicine, University of Cambridge, Francis Crick Avenue, Trumpington, Cambridge CB2 0QH, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Rashid+ZM%22">Rashid ZM</searchLink>; Department of Physics and Astronomy, and LaserLaB Amsterdam, Vrije Universiteit Amsterdam, De Boelelaan 1100, 1081 HZ Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Smitskamp+Q%22">Smitskamp Q</searchLink>; Department of Physics and Astronomy, and LaserLaB Amsterdam, Vrije Universiteit Amsterdam, De Boelelaan 1100, 1081 HZ Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Rivas+P%22">Rivas P</searchLink>; Department of Physics and Astronomy, and LaserLaB Amsterdam, Vrije Universiteit Amsterdam, De Boelelaan 1100, 1081 HZ Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Papini+FS%22">Papini FS</searchLink>; Junior Research Group 2, Interdisciplinary Center for Clinical Research, Friedrich-Alexander-University Erlangen-Nürnberg, Cauerstr. 3, 91058 Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Broedersz+CP%22">Broedersz CP</searchLink>; Department of Physics and Astronomy, and LaserLaB Amsterdam, Vrije Universiteit Amsterdam, De Boelelaan 1100, 1081 HZ Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Roos+WH%22">Roos WH</searchLink>; Moleculaire Biofysica, Zernike Instituut, Rijksuniversiteit Groningen, Nijenborgh 3, 9747 AG Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Modis+Y%22">Modis Y</searchLink>; Molecular Immunity Unit, Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology,Francis Crick Avenue, Trumpington, Cambridge CB2 0QH, United Kingdom.; Cambridge Institute of Therapeutic Immunology and Infectious Disease, Department of Medicine, University of Cambridge, Francis Crick Avenue, Trumpington, Cambridge CB2 0QH, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Dulin+D%22">Dulin D</searchLink>; Department of Physics and Astronomy, and LaserLaB Amsterdam, Vrije Universiteit Amsterdam, De Boelelaan 1100, 1081 HZ Amsterdam, The Netherlands.; Junior Research Group 2, Interdisciplinary Center for Clinical Research, Friedrich-Alexander-University Erlangen-Nürnberg, Cauerstr. 3, 91058 Erlangen, Germany.
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