High-fat diet causes rapid loss of intestinal group 3 innate lymphoid cells through microbiota-driven inflammation and mitochondrial stress.
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| Title: | High-fat diet causes rapid loss of intestinal group 3 innate lymphoid cells through microbiota-driven inflammation and mitochondrial stress. |
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| Authors: | Torrico EC; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Kaptein P; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Laalouhmi F; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Faculty of Medical Sciences, UM6P Hospitals, Mohammed VI Polytechnic University, 43150 Benguerir, Morocco., Mitsialis V; Division of Gastroenterology, Brigham and Women's Hospital, Boston, MA, USA; Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., El Guendouzi S; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Faculty of Medical Sciences, UM6P Hospitals, Mohammed VI Polytechnic University, 43150 Benguerir, Morocco., El Khayari A; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Faculty of Medical Sciences, UM6P Hospitals, Mohammed VI Polytechnic University, 43150 Benguerir, Morocco., El Baha C; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Faculty of Medical Sciences, UM6P Hospitals, Mohammed VI Polytechnic University, 43150 Benguerir, Morocco., Htite ED; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Chawluk S; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Gauthier CD; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Djekidel NM; Howard Hughes Medical Institute, Boston Children's Hospital, Boston, MA 02115, USA; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA; Division of Hematology/Oncology, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA., Da Silva P; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Lanser TB; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Gupta A; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Sivanathan K; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., De Oliveira MG; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Maghzi AH; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Tavakkoli A; Division of General and Gastrointestinal Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Sojoodi M; Division of Gastrointestinal and Oncologic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Qadan M; Division of Gastrointestinal and Oncologic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Liu S; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Rezende RM; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Cox LM; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Bod L; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Schnell A; Whitehead institute and Massachusetts Institute of Technology, Cambridge, MA, USA., Song A; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Pierre I; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Jabbari-Lak P; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Heil VV; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Lemos LS; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Keegan J; Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Nguyen JP; Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Cahill LA; Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Kumar RK; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Kuhn C; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Parmar G; University of Ottawa, Center for cardiovascular diseases, Ottawa, Canada., Murugaiyan G; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Lederer JA; Whitehead institute and Massachusetts Institute of Technology, Cambridge, MA, USA., Snapper SB; Faculty of Medical Sciences, UM6P Hospitals, Mohammed VI Polytechnic University, 43150 Benguerir, Morocco., Nowarski R; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., El Fatimy R; Faculty of Medical Sciences, UM6P Hospitals, Mohammed VI Polytechnic University, 43150 Benguerir, Morocco., Weiner HL; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Boulenouar S; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: sboulenouar@bwh.harvard.edu. |
| Source: | Immunity [Immunity] 2026 Apr 14; Vol. 59 (4), pp. 988-1005.e9. Date of Electronic Publication: 2026 Mar 30. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4180 (Electronic) Linking ISSN: 10747613 NLM ISO Abbreviation: Immunity Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41916320 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: High-fat diet causes rapid loss of intestinal group 3 innate lymphoid cells through microbiota-driven inflammation and mitochondrial stress. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Torrico+EC%22">Torrico EC</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kaptein+P%22">Kaptein P</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Laalouhmi+F%22">Laalouhmi F</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Faculty of Medical Sciences, UM6P Hospitals, Mohammed VI Polytechnic University, 43150 Benguerir, Morocco.<br /><searchLink fieldCode="AU" term="%22Mitsialis+V%22">Mitsialis V</searchLink>; 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Faculty of Medical Sciences, UM6P Hospitals, Mohammed VI Polytechnic University, 43150 Benguerir, Morocco.<br /><searchLink fieldCode="AU" term="%22Htite+ED%22">Htite ED</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Chawluk+S%22">Chawluk S</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Gauthier+CD%22">Gauthier CD</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Djekidel+NM%22">Djekidel NM</searchLink>; Howard Hughes Medical Institute, Boston Children's Hospital, Boston, MA 02115, USA; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA; Division of Hematology/Oncology, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Da+Silva+P%22">Da Silva P</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Lanser+TB%22">Lanser TB</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Gupta+A%22">Gupta A</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sivanathan+K%22">Sivanathan K</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22De+Oliveira+MG%22">De Oliveira MG</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Maghzi+AH%22">Maghzi AH</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Tavakkoli+A%22">Tavakkoli A</searchLink>; Division of General and Gastrointestinal Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Sojoodi+M%22">Sojoodi M</searchLink>; Division of Gastrointestinal and Oncologic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Qadan+M%22">Qadan M</searchLink>; Division of Gastrointestinal and Oncologic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Liu+S%22">Liu S</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Rezende+RM%22">Rezende RM</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Cox+LM%22">Cox LM</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bod+L%22">Bod L</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Schnell+A%22">Schnell A</searchLink>; Whitehead institute and Massachusetts Institute of Technology, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Song+A%22">Song A</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Pierre+I%22">Pierre I</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Jabbari-Lak+P%22">Jabbari-Lak P</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Heil+VV%22">Heil VV</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Lemos+LS%22">Lemos LS</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Keegan+J%22">Keegan J</searchLink>; Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+JP%22">Nguyen JP</searchLink>; 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Whitehead institute and Massachusetts Institute of Technology, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Snapper+SB%22">Snapper SB</searchLink>; Faculty of Medical Sciences, UM6P Hospitals, Mohammed VI Polytechnic University, 43150 Benguerir, Morocco.<br /><searchLink fieldCode="AU" term="%22Nowarski+R%22">Nowarski R</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22El+Fatimy+R%22">El Fatimy R</searchLink>; Faculty of Medical Sciences, UM6P Hospitals, Mohammed VI Polytechnic University, 43150 Benguerir, Morocco.<br /><searchLink fieldCode="AU" term="%22Weiner+HL%22">Weiner HL</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Boulenouar+S%22">Boulenouar S</searchLink>; Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: sboulenouar@bwh.harvard.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229432918%22">Immunity</searchLink> [Immunity] 2026 Apr 14; Vol. 59 (4), pp. 988-1005.e9. <i>Date of Electronic Publication: </i>2026 Mar 30. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9432918 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-4180 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210747613%22">10747613 </searchLink><i>NLM ISO Abbreviation: </i>Immunity <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41916320 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.immuni.2026.02.014 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 988 Titles: – TitleFull: High-fat diet causes rapid loss of intestinal group 3 innate lymphoid cells through microbiota-driven inflammation and mitochondrial stress. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Torrico EC – PersonEntity: Name: NameFull: Kaptein P – PersonEntity: Name: NameFull: Laalouhmi F – PersonEntity: Name: NameFull: Mitsialis V – PersonEntity: Name: NameFull: El Guendouzi S – PersonEntity: Name: NameFull: El Khayari A – PersonEntity: Name: NameFull: El Baha C – PersonEntity: Name: NameFull: Htite ED – PersonEntity: Name: NameFull: Chawluk S – PersonEntity: Name: NameFull: Gauthier CD – PersonEntity: Name: NameFull: Djekidel NM – PersonEntity: Name: NameFull: Da Silva P – PersonEntity: Name: NameFull: Lanser TB – PersonEntity: Name: NameFull: Gupta A – PersonEntity: Name: NameFull: Sivanathan K – PersonEntity: Name: NameFull: De Oliveira MG – PersonEntity: Name: NameFull: Maghzi AH – PersonEntity: Name: NameFull: Tavakkoli A – PersonEntity: Name: NameFull: Sojoodi M – PersonEntity: Name: NameFull: Qadan M – PersonEntity: Name: NameFull: Liu S – PersonEntity: Name: NameFull: Rezende RM – PersonEntity: Name: NameFull: Cox LM – PersonEntity: Name: NameFull: Bod L – PersonEntity: Name: NameFull: Schnell A – PersonEntity: Name: NameFull: Song A – PersonEntity: Name: NameFull: Pierre I – PersonEntity: Name: NameFull: Jabbari-Lak P – PersonEntity: Name: NameFull: Heil VV – PersonEntity: Name: NameFull: Lemos LS – PersonEntity: Name: NameFull: Keegan J – PersonEntity: Name: NameFull: Nguyen JP – PersonEntity: Name: NameFull: Cahill LA – PersonEntity: Name: NameFull: Kumar RK – PersonEntity: Name: NameFull: Kuhn C – PersonEntity: Name: NameFull: Parmar G – PersonEntity: Name: NameFull: Murugaiyan G – PersonEntity: Name: NameFull: Lederer JA – PersonEntity: Name: NameFull: Snapper SB – PersonEntity: Name: NameFull: Nowarski R – PersonEntity: Name: NameFull: El Fatimy R – PersonEntity: Name: NameFull: Weiner HL – PersonEntity: Name: NameFull: Boulenouar S IsPartOfRelationships: – BibEntity: Dates: – D: 14 M: 04 Text: 2026 Apr 14 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1097-4180 Numbering: – Type: volume Value: 59 – Type: issue Value: 4 Titles: – TitleFull: Immunity Type: main |
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