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Lipidation of a nuclear localization sequence enhances broad-spectrum antimicrobial activity: synthesis, characterization, and in silico analysis.

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Title: Lipidation of a nuclear localization sequence enhances broad-spectrum antimicrobial activity: synthesis, characterization, and in silico analysis.
Authors: Maharani R; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, West Java, Indonesia.; Central Laboratory, Universitas Padjadjaran, West Java, Indonesia.; Center of Exploration and Utilization of Natural Resources and Environment, Universitas Padjadjaran, West Java, Indonesia., Fakih TM; Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Islam Bandung, West Java, Indonesia., Muhajir MI; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, West Java, Indonesia.; Central Laboratory, Universitas Padjadjaran, West Java, Indonesia., Rizqiyani AF; Central Laboratory, Universitas Padjadjaran, West Java, Indonesia., Hidayat AT; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, West Java, Indonesia.; Central Laboratory, Universitas Padjadjaran, West Java, Indonesia.; Center of Exploration and Utilization of Natural Resources and Environment, Universitas Padjadjaran, West Java, Indonesia., Aditama R; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Institut Teknologi Bandung, West Java, Indonesia., Lestari R; Faculty of Pharmacy, Universitas of Indonesia, Depok City, Indonesia., Utomo DIS; Research Center for Vaccine and Drug Development, Badan Riset dan Inovasi Nasional (BRIN), South Tangerang, Indonesia., Tarwadi T; Research Center for Vaccine and Drug Development, Badan Riset dan Inovasi Nasional (BRIN), South Tangerang, Indonesia.
Source: Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2026 Dec; Vol. 54 (1), pp. 264-288. Date of Electronic Publication: 2026 Mar 31.
Publication Type: Journal Article
Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101594777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2169-141X (Electronic) Linking ISSN: 21691401 NLM ISO Abbreviation: Artif Cells Nanomed Biotechnol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2169-141X
DOI:10.1080/21691401.2026.2649071