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Lipidation of a nuclear localization sequence enhances broad-spectrum antimicrobial activity: synthesis, characterization, and in silico analysis.

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Title: Lipidation of a nuclear localization sequence enhances broad-spectrum antimicrobial activity: synthesis, characterization, and in silico analysis.
Authors: Maharani R; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, West Java, Indonesia.; Central Laboratory, Universitas Padjadjaran, West Java, Indonesia.; Center of Exploration and Utilization of Natural Resources and Environment, Universitas Padjadjaran, West Java, Indonesia., Fakih TM; Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Islam Bandung, West Java, Indonesia., Muhajir MI; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, West Java, Indonesia.; Central Laboratory, Universitas Padjadjaran, West Java, Indonesia., Rizqiyani AF; Central Laboratory, Universitas Padjadjaran, West Java, Indonesia., Hidayat AT; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, West Java, Indonesia.; Central Laboratory, Universitas Padjadjaran, West Java, Indonesia.; Center of Exploration and Utilization of Natural Resources and Environment, Universitas Padjadjaran, West Java, Indonesia., Aditama R; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Institut Teknologi Bandung, West Java, Indonesia., Lestari R; Faculty of Pharmacy, Universitas of Indonesia, Depok City, Indonesia., Utomo DIS; Research Center for Vaccine and Drug Development, Badan Riset dan Inovasi Nasional (BRIN), South Tangerang, Indonesia., Tarwadi T; Research Center for Vaccine and Drug Development, Badan Riset dan Inovasi Nasional (BRIN), South Tangerang, Indonesia.
Source: Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2026 Dec; Vol. 54 (1), pp. 264-288. Date of Electronic Publication: 2026 Mar 31.
Publication Type: Journal Article
Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101594777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2169-141X (Electronic) Linking ISSN: 21691401 NLM ISO Abbreviation: Artif Cells Nanomed Biotechnol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Lipidation of a nuclear localization sequence enhances broad-spectrum antimicrobial activity: synthesis, characterization, and in silico analysis.
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  Data: <searchLink fieldCode="AU" term="%22Maharani+R%22">Maharani R</searchLink>; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, West Java, Indonesia.; Central Laboratory, Universitas Padjadjaran, West Java, Indonesia.; Center of Exploration and Utilization of Natural Resources and Environment, Universitas Padjadjaran, West Java, Indonesia.<br /><searchLink fieldCode="AU" term="%22Fakih+TM%22">Fakih TM</searchLink>; Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Islam Bandung, West Java, Indonesia.<br /><searchLink fieldCode="AU" term="%22Muhajir+MI%22">Muhajir MI</searchLink>; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, West Java, Indonesia.; Central Laboratory, Universitas Padjadjaran, West Java, Indonesia.<br /><searchLink fieldCode="AU" term="%22Rizqiyani+AF%22">Rizqiyani AF</searchLink>; Central Laboratory, Universitas Padjadjaran, West Java, Indonesia.<br /><searchLink fieldCode="AU" term="%22Hidayat+AT%22">Hidayat AT</searchLink>; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, West Java, Indonesia.; Central Laboratory, Universitas Padjadjaran, West Java, Indonesia.; Center of Exploration and Utilization of Natural Resources and Environment, Universitas Padjadjaran, West Java, Indonesia.<br /><searchLink fieldCode="AU" term="%22Aditama+R%22">Aditama R</searchLink>; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Institut Teknologi Bandung, West Java, Indonesia.<br /><searchLink fieldCode="AU" term="%22Lestari+R%22">Lestari R</searchLink>; Faculty of Pharmacy, Universitas of Indonesia, Depok City, Indonesia.<br /><searchLink fieldCode="AU" term="%22Utomo+DIS%22">Utomo DIS</searchLink>; Research Center for Vaccine and Drug Development, Badan Riset dan Inovasi Nasional (BRIN), South Tangerang, Indonesia.<br /><searchLink fieldCode="AU" term="%22Tarwadi+T%22">Tarwadi T</searchLink>; Research Center for Vaccine and Drug Development, Badan Riset dan Inovasi Nasional (BRIN), South Tangerang, Indonesia.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Taylor+%26+Francis%22">Taylor & Francis </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101594777 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2169-141X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221691401%22">21691401 </searchLink><i>NLM ISO Abbreviation: </i>Artif Cells Nanomed Biotechnol <i>Subsets: </i>MEDLINE
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        Value: 10.1080/21691401.2026.2649071
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      – Code: eng
        Text: English
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        StartPage: 264
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              Text: 2026 Dec
              Type: published
              Y: 2026
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