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Computational-guided semi-rational design to reprogram phospholipase D into industrially robust enzyme.

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Title: Computational-guided semi-rational design to reprogram phospholipase D into industrially robust enzyme.
Authors: Kong XL; Key Laboratory of Carbohydrate Chemistry and Biotechnology of Ministry of Education, School of Life Sciences and Health Engineering, Jiangnan University, Wuxi 214122, PR China; National Engineering Research Center for Cereal Fermentation and Food Biomanufacturing, School of Biotechnology, Jiangnan University, Wuxi 214122, PR China. Electronic address: 3171281291@qq.com., Zhang P; Key Laboratory of Carbohydrate Chemistry and Biotechnology of Ministry of Education, School of Life Sciences and Health Engineering, Jiangnan University, Wuxi 214122, PR China; National Key Laboratory for Development and Utilization of Forest Food Resources, Zhejiang A&F University, Hangzhou 311300, PR China. Electronic address: 2652726703@qq.com., Qin ZQ; Key Laboratory of Carbohydrate Chemistry and Biotechnology of Ministry of Education, School of Life Sciences and Health Engineering, Jiangnan University, Wuxi 214122, PR China; National Engineering Research Center for Cereal Fermentation and Food Biomanufacturing, School of Biotechnology, Jiangnan University, Wuxi 214122, PR China. Electronic address: 76674326@qq.com., Su C; Key Laboratory of Carbohydrate Chemistry and Biotechnology of Ministry of Education, School of Life Sciences and Health Engineering, Jiangnan University, Wuxi 214122, PR China; Institute of Future Food Technology, JITRI, Yixing 214200, PR China. Electronic address: 174020590@qq.com., Li H; Key Laboratory of Carbohydrate Chemistry and Biotechnology of Ministry of Education, School of Life Sciences and Health Engineering, Jiangnan University, Wuxi 214122, PR China; Institute of Future Food Technology, JITRI, Yixing 214200, PR China. Electronic address: liheng@jiangnan.edu.cn., Lu ZM; National Engineering Research Center for Cereal Fermentation and Food Biomanufacturing, School of Biotechnology, Jiangnan University, Wuxi 214122, PR China. Electronic address: zmlu@jiangnan.edu.cn., Gong JS; Key Laboratory of Carbohydrate Chemistry and Biotechnology of Ministry of Education, School of Life Sciences and Health Engineering, Jiangnan University, Wuxi 214122, PR China; Institute of Future Food Technology, JITRI, Yixing 214200, PR China; Shandong Kunda Biotechnology Co., Ltd, Linyi 276400, PR China. Electronic address: jinsonggong.bio@hotmail.com., Xu ZH; Institute of Future Food Technology, JITRI, Yixing 214200, PR China; National Engineering Research Center for Cereal Fermentation and Food Biomanufacturing, School of Biotechnology, Jiangnan University, Wuxi 214122, PR China; Innovation Center for Advanced Brewing Science and Technology, College of Biomass Science and Engineering, Sichuan University, Chengdu 610065, PR China. Electronic address: zhenghxu@jiangnan.edu.cn., Shi JS; Key Laboratory of Carbohydrate Chemistry and Biotechnology of Ministry of Education, School of Life Sciences and Health Engineering, Jiangnan University, Wuxi 214122, PR China; Institute of Future Food Technology, JITRI, Yixing 214200, PR China. Electronic address: shijs@163.com.
Source: Bioresource technology [Bioresour Technol] 2026 Jul; Vol. 451, pp. 134528. Date of Electronic Publication: 2026 Mar 29.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Applied Science Country of Publication: England NLM ID: 9889523 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2976 (Electronic) Linking ISSN: 09608524 NLM ISO Abbreviation: Bioresour Technol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Computational-guided semi-rational design to reprogram phospholipase D into industrially robust enzyme.
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  Data: <searchLink fieldCode="AU" term="%22Kong+XL%22">Kong XL</searchLink>; Key Laboratory of Carbohydrate Chemistry and Biotechnology of Ministry of Education, School of Life Sciences and Health Engineering, Jiangnan University, Wuxi 214122, PR China; National Engineering Research Center for Cereal Fermentation and Food Biomanufacturing, School of Biotechnology, Jiangnan University, Wuxi 214122, PR China. Electronic address: 3171281291@qq.com.<br /><searchLink fieldCode="AU" term="%22Zhang+P%22">Zhang P</searchLink>; Key Laboratory of Carbohydrate Chemistry and Biotechnology of Ministry of Education, School of Life Sciences and Health Engineering, Jiangnan University, Wuxi 214122, PR China; National Key Laboratory for Development and Utilization of Forest Food Resources, Zhejiang A&F University, Hangzhou 311300, PR China. Electronic address: 2652726703@qq.com.<br /><searchLink fieldCode="AU" term="%22Qin+ZQ%22">Qin ZQ</searchLink>; Key Laboratory of Carbohydrate Chemistry and Biotechnology of Ministry of Education, School of Life Sciences and Health Engineering, Jiangnan University, Wuxi 214122, PR China; National Engineering Research Center for Cereal Fermentation and Food Biomanufacturing, School of Biotechnology, Jiangnan University, Wuxi 214122, PR China. Electronic address: 76674326@qq.com.<br /><searchLink fieldCode="AU" term="%22Su+C%22">Su C</searchLink>; Key Laboratory of Carbohydrate Chemistry and Biotechnology of Ministry of Education, School of Life Sciences and Health Engineering, Jiangnan University, Wuxi 214122, PR China; Institute of Future Food Technology, JITRI, Yixing 214200, PR China. Electronic address: 174020590@qq.com.<br /><searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; Key Laboratory of Carbohydrate Chemistry and Biotechnology of Ministry of Education, School of Life Sciences and Health Engineering, Jiangnan University, Wuxi 214122, PR China; Institute of Future Food Technology, JITRI, Yixing 214200, PR China. Electronic address: liheng@jiangnan.edu.cn.<br /><searchLink fieldCode="AU" term="%22Lu+ZM%22">Lu ZM</searchLink>; National Engineering Research Center for Cereal Fermentation and Food Biomanufacturing, School of Biotechnology, Jiangnan University, Wuxi 214122, PR China. Electronic address: zmlu@jiangnan.edu.cn.<br /><searchLink fieldCode="AU" term="%22Gong+JS%22">Gong JS</searchLink>; Key Laboratory of Carbohydrate Chemistry and Biotechnology of Ministry of Education, School of Life Sciences and Health Engineering, Jiangnan University, Wuxi 214122, PR China; Institute of Future Food Technology, JITRI, Yixing 214200, PR China; Shandong Kunda Biotechnology Co., Ltd, Linyi 276400, PR China. Electronic address: jinsonggong.bio@hotmail.com.<br /><searchLink fieldCode="AU" term="%22Xu+ZH%22">Xu ZH</searchLink>; Institute of Future Food Technology, JITRI, Yixing 214200, PR China; National Engineering Research Center for Cereal Fermentation and Food Biomanufacturing, School of Biotechnology, Jiangnan University, Wuxi 214122, PR China; Innovation Center for Advanced Brewing Science and Technology, College of Biomass Science and Engineering, Sichuan University, Chengdu 610065, PR China. Electronic address: zhenghxu@jiangnan.edu.cn.<br /><searchLink fieldCode="AU" term="%22Shi+JS%22">Shi JS</searchLink>; Key Laboratory of Carbohydrate Chemistry and Biotechnology of Ministry of Education, School of Life Sciences and Health Engineering, Jiangnan University, Wuxi 214122, PR China; Institute of Future Food Technology, JITRI, Yixing 214200, PR China. Electronic address: shijs@163.com.
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  Data: <searchLink fieldCode="JN" term="%229889523%22">Bioresource technology</searchLink> [Bioresour Technol] 2026 Jul; Vol. 451, pp. 134528. <i>Date of Electronic Publication: </i>2026 Mar 29.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Applied+Science%22">Elsevier Applied Science </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9889523 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-2976 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209608524%22">09608524 </searchLink><i>NLM ISO Abbreviation: </i>Bioresour Technol <i>Subsets: </i>MEDLINE
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1016/j.biortech.2026.134528
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      – Code: eng
        Text: English
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        StartPage: 134528
    Titles:
      – TitleFull: Computational-guided semi-rational design to reprogram phospholipase D into industrially robust enzyme.
        Type: main
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      – PersonEntity:
          Name:
            NameFull: Kong XL
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          Name:
            NameFull: Zhang P
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            NameFull: Qin ZQ
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            NameFull: Su C
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            NameFull: Li H
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            NameFull: Lu ZM
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            NameFull: Gong JS
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            NameFull: Xu ZH
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            – D: 01
              M: 07
              Text: 2026 Jul
              Type: published
              Y: 2026
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              Value: 1873-2976
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              Value: 451
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            – TitleFull: Bioresource technology
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