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Mirror-enhanced 4Pi-SMLM with one objective enables isotropic nanoscale imaging.

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Title: Mirror-enhanced 4Pi-SMLM with one objective enables isotropic nanoscale imaging.
Authors: Yu Z; Fudan University, Shanghai, China.; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China., Zheng B; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China., Zhan Y; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China., Li S; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China., Wang X; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China., Dai Q; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China., Chen Y; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China., Wei Z; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China., Zhao W; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China., Chen L; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China., Tang J; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China., Xia T; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China., He L; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China., Liu C; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China.; Research Center for Industries of the Future, Westlake University, Hangzhou, China., Wu X; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China., Yu X; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China.; Research Center for Industries of the Future, Westlake University, Hangzhou, China., Zhang Y; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China. zhangyongdeng@westlake.edu.cn.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China. zhangyongdeng@westlake.edu.cn.; Research Center for Industries of the Future, Westlake University, Hangzhou, China. zhangyongdeng@westlake.edu.cn.
Source: Nature biotechnology [Nat Biotechnol] 2026 Mar 31. Date of Electronic Publication: 2026 Mar 31.
Publication Type: Journal Article
Journal Info: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Yu+Z%22">Yu Z</searchLink>; Fudan University, Shanghai, China.; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zheng+B%22">Zheng B</searchLink>; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhan+Y%22">Zhan Y</searchLink>; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Dai+Q%22">Dai Q</searchLink>; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wei+Z%22">Wei Z</searchLink>; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhao+W%22">Zhao W</searchLink>; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+L%22">Chen L</searchLink>; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Tang+J%22">Tang J</searchLink>; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Xia+T%22">Xia T</searchLink>; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22He+L%22">He L</searchLink>; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Liu+C%22">Liu C</searchLink>; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China.; Research Center for Industries of the Future, Westlake University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wu+X%22">Wu X</searchLink>; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Yu+X%22">Yu X</searchLink>; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China.; Research Center for Industries of the Future, Westlake University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; State Key Laboratory of Gene Expression, School of Life Sciences, Westlake University, Hangzhou, China. zhangyongdeng@westlake.edu.cn.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China. zhangyongdeng@westlake.edu.cn.; Research Center for Industries of the Future, Westlake University, Hangzhou, China. zhangyongdeng@westlake.edu.cn.
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