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Development of a Taste-Masked, Dose-Flexible, Multiparticulate Pediatric Dosage Form: Case Study of Crizotinib, a Challenging Pediatric Formulation.

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Title: Development of a Taste-Masked, Dose-Flexible, Multiparticulate Pediatric Dosage Form: Case Study of Crizotinib, a Challenging Pediatric Formulation.
Authors: Bartlett JA; Global Research and Development, Pharmaceutical Sciences, Pfizer Inc., Groton, CT, USA. jeremy.a.bartlett@pfizer.com., Culver N; Global Research and Development, Pharmaceutical Sciences, Pfizer Inc., Groton, CT, USA., Santangelo M; Global Research and Development, Pharmaceutical Sciences, Pfizer Inc., Groton, CT, USA., Prpich A; Global Research and Development, Pharmaceutical Sciences, Pfizer Inc., Groton, CT, USA., Long E; Global Research and Development, Pharmaceutical Sciences, Pfizer Inc., Groton, CT, USA., Sagawa K; Global Research and Development, Pharmaceutical Sciences, Pfizer Inc., Groton, CT, USA., Shanker R; Global Research and Development, Pharmaceutical Sciences, Pfizer Inc., Groton, CT, USA., Xu H; Global Research and Development, Clinical Pharmacology, Pfizer Inc., San Diego, CA, USA., Wilner K; Global Research and Development, Clinical, Pfizer Inc., San Diego, CA, USA.
Source: Pharmaceutical medicine [Pharmaceut Med] 2026 May; Vol. 40 (3), pp. 193-207. Date of Electronic Publication: 2026 Apr 01.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 101471195 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1993 (Electronic) Linking ISSN: 11782595 NLM ISO Abbreviation: Pharmaceut Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Bartlett+JA%22">Bartlett JA</searchLink>; Global Research and Development, Pharmaceutical Sciences, Pfizer Inc., Groton, CT, USA. jeremy.a.bartlett@pfizer.com.<br /><searchLink fieldCode="AU" term="%22Culver+N%22">Culver N</searchLink>; Global Research and Development, Pharmaceutical Sciences, Pfizer Inc., Groton, CT, USA.<br /><searchLink fieldCode="AU" term="%22Santangelo+M%22">Santangelo M</searchLink>; Global Research and Development, Pharmaceutical Sciences, Pfizer Inc., Groton, CT, USA.<br /><searchLink fieldCode="AU" term="%22Prpich+A%22">Prpich A</searchLink>; Global Research and Development, Pharmaceutical Sciences, Pfizer Inc., Groton, CT, USA.<br /><searchLink fieldCode="AU" term="%22Long+E%22">Long E</searchLink>; Global Research and Development, Pharmaceutical Sciences, Pfizer Inc., Groton, CT, USA.<br /><searchLink fieldCode="AU" term="%22Sagawa+K%22">Sagawa K</searchLink>; Global Research and Development, Pharmaceutical Sciences, Pfizer Inc., Groton, CT, USA.<br /><searchLink fieldCode="AU" term="%22Shanker+R%22">Shanker R</searchLink>; Global Research and Development, Pharmaceutical Sciences, Pfizer Inc., Groton, CT, USA.<br /><searchLink fieldCode="AU" term="%22Xu+H%22">Xu H</searchLink>; Global Research and Development, Clinical Pharmacology, Pfizer Inc., San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Wilner+K%22">Wilner K</searchLink>; Global Research and Development, Clinical, Pfizer Inc., San Diego, CA, USA.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Adis%2C+Springer+International%22">Adis, Springer International </searchLink><i>Country of Publication: </i>New Zealand <i>NLM ID: </i>101471195 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1179-1993 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211782595%22">11782595 </searchLink><i>NLM ISO Abbreviation: </i>Pharmaceut Med <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s40290-026-00604-2
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      – TitleFull: Development of a Taste-Masked, Dose-Flexible, Multiparticulate Pediatric Dosage Form: Case Study of Crizotinib, a Challenging Pediatric Formulation.
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              Text: 2026 May
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