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2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19: Antiviral Treatment for Mild to Moderate COVID-19 in Adults.

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Title: 2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19: Antiviral Treatment for Mild to Moderate COVID-19 in Adults.
Authors: Shumaker AH; Department of Medicine, Case Western Reserve University, School of Medicine, Cleveland, Ohio, USA.; Department of Medicine, VA Northeast Ohio Healthcare System, Cleveland, Ohio, USA., Bhimraj A; Division of Infectious Diseases, Houston Methodist Hospital, Houston, Texas, USA., Bedimo R; Department of Medicine, UT Southwestern/VA North Texas Health Care System, Dallas, Texas, USA., Cheng VC; Department of Microbiology, Queen Mary Hospital, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China., Chew KW; Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA., Daar ES; Department of Medicine, Harbor-UCLA Medical Center, Torrance, California, USA., Glidden DV; Department of Epidemiology and Biostatistics, UCSF, San Francisco, California, USA., Shafer RW; Department of Medicine, Stanford University, Palo Alto, California, USA., Tien PC; Department of Medicine, UCSF/VA San Francisco Health Care System, San Francisco, California, USA., Baden LR; Harvard Medical School, Boston, Massachusetts, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA., Cawcutt K; Division of Infectious Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA., Chiotos K; Department of Anesthesiology and Critical Care, Children's Hospital of Philadelphia/University of Pennsylvania, Philadelphia, Pennsylvania, USA., Dzierba AL; Department of Medicine, New York University Grossman School of Medicine, New York City, New York, USA., Hardy EJ; Departments of Medicine and Obstetrics and Gynecology, Brown University, Providence, Rhode Island, USA., Johnson S; Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado, USA., Kim AY; Harvard Medical School, Boston, Massachusetts, USA.; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA., MacBrayne C; Department of Pharmacy, Children's Hospital Colorado, Aurora, Colorado, USA., Martin GS; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Emory University, Atlanta, Georgia, USA., Nadig N; Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Nakamura MM; Antimicrobial Stewardship Program and Division of Infectious Diseases, Boston Children's Hospital, Boston, Massachusetts, USA.; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA., Oliveira CR; Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA., Pearson JC; Department of Pharmacy, Brigham and Women's Hospital, Boston, Massachusetts, USA., Riley L; New York-Presbyterian Hospital/Weill Cornell Medical Center, New York City, New York, USA.; Department of Obstetrics and Gynecology, Weill Cornell Medicine, New York City, New York, USA., Shoham S; Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Tebas P; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Willis Z; Department of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA., Wolf J; Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Loveless J; Clinical Affairs and Practice Guidelines, Infectious Diseases Society of America, Arlington, Virginia, USA., Morgan RL; Department of Medicine, Case Western Reserve University, School of Medicine, Cleveland, Ohio, USA.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada., Falck-Ytter Y; Department of Medicine, Case Western Reserve University, School of Medicine, Cleveland, Ohio, USA.; Department of Medicine, VA Northeast Ohio Healthcare System, Cleveland, Ohio, USA., Gandhi RT; Harvard Medical School, Boston, Massachusetts, USA.; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
Source: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2026 Apr 01. Date of Electronic Publication: 2026 Apr 01.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9203213 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-6591 (Electronic) Linking ISSN: 10584838 NLM ISO Abbreviation: Clin Infect Dis Subsets: MEDLINE
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Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Emory University, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Nadig+N%22">Nadig N</searchLink>; Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Nakamura+MM%22">Nakamura MM</searchLink>; Antimicrobial Stewardship Program and Division of Infectious Diseases, Boston Children's Hospital, Boston, Massachusetts, USA.; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Oliveira+CR%22">Oliveira CR</searchLink>; Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Pearson+JC%22">Pearson JC</searchLink>; Department of Pharmacy, Brigham and Women's Hospital, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Riley+L%22">Riley L</searchLink>; New York-Presbyterian Hospital/Weill Cornell Medical Center, New York City, New York, USA.; Department of Obstetrics and Gynecology, Weill Cornell Medicine, New York City, New York, USA.<br /><searchLink fieldCode="AU" term="%22Shoham+S%22">Shoham S</searchLink>; Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Tebas+P%22">Tebas P</searchLink>; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Willis+Z%22">Willis Z</searchLink>; Department of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Wolf+J%22">Wolf J</searchLink>; Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Loveless+J%22">Loveless J</searchLink>; Clinical Affairs and Practice Guidelines, Infectious Diseases Society of America, Arlington, Virginia, USA.<br /><searchLink fieldCode="AU" term="%22Morgan+RL%22">Morgan RL</searchLink>; Department of Medicine, Case Western Reserve University, School of Medicine, Cleveland, Ohio, USA.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Falck-Ytter+Y%22">Falck-Ytter Y</searchLink>; Department of Medicine, Case Western Reserve University, School of Medicine, Cleveland, Ohio, USA.; Department of Medicine, VA Northeast Ohio Healthcare System, Cleveland, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Gandhi+RT%22">Gandhi RT</searchLink>; Harvard Medical School, Boston, Massachusetts, USA.; Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
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