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Historic 1994 influenza vaccine cohorts define breadth of antibody and B cell responses toward future influenza A and B viruses.

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Title: Historic 1994 influenza vaccine cohorts define breadth of antibody and B cell responses toward future influenza A and B viruses.
Authors: Nguyen THO; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia., Foo IJH; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia., Purcell RA; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia., Tan HX; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia., Deliyannis G; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia., Zhang W; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia., Carolan L; WHO Collaborating Centre for Reference and Research on Influenza, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia., Hadiprodjo AJ; WHO Collaborating Centre for Reference and Research on Influenza, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia., Huang HH; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia., Allen LF; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia., Hagen RR; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia., Aurelia LC; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia., McQuilten HA; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia., Rowntree LC; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia., Kedzierski L; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia., Wilks SH; Department of Electrical and Electronic Engineering, University of Melbourne, Melbourne, Victoria 3010, Australia.; Victorian Infectious Diseases Reference Laboratory, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia., McKay MR; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.; Department of Electrical and Electronic Engineering, University of Melbourne, Melbourne, Victoria 3010, Australia.; Victorian Infectious Diseases Reference Laboratory, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia., Tannock GA; Burnet Institute, Melbourne, Victoria 3004, Australia., Kent SJ; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.; Melbourne Sexual Health Centre and Department of Infectious Diseases, Alfred Health, Central Clinical School, Monash University, Melbourne, Victoria 3004, Australia., Laurie K; CSL Seqirus Ltd., Melbourne, Victoria 3000, Australia., Fox A; WHO Collaborating Centre for Reference and Research on Influenza, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.; Department of Infectious Diseases, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia., Rockman S; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.; CSL Seqirus Ltd., Melbourne, Victoria 3000, Australia., Brown LE; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.; Institute for Vaccine Research and Development, Hokkaido University, Sapporo, Hokkaido 060-0808, Japan., Chung AW; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia., Wheatley AK; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia., Kedzierska K; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.; Institute for Vaccine Research and Development, Hokkaido University, Sapporo, Hokkaido 060-0808, Japan.
Source: Science translational medicine [Sci Transl Med] 2026 Apr; Vol. 18 (843), pp. eaea8621. Date of Electronic Publication: 2026 Apr 01.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
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  Data: Historic 1994 influenza vaccine cohorts define breadth of antibody and B cell responses toward future influenza A and B viruses.
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  Data: <searchLink fieldCode="AU" term="%22Nguyen+THO%22">Nguyen THO</searchLink>; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Foo+IJH%22">Foo IJH</searchLink>; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Purcell+RA%22">Purcell RA</searchLink>; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Tan+HX%22">Tan HX</searchLink>; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Deliyannis+G%22">Deliyannis G</searchLink>; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Zhang+W%22">Zhang W</searchLink>; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Carolan+L%22">Carolan L</searchLink>; WHO Collaborating Centre for Reference and Research on Influenza, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Hadiprodjo+AJ%22">Hadiprodjo AJ</searchLink>; WHO Collaborating Centre for Reference and Research on Influenza, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Huang+HH%22">Huang HH</searchLink>; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Allen+LF%22">Allen LF</searchLink>; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Hagen+RR%22">Hagen RR</searchLink>; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Aurelia+LC%22">Aurelia LC</searchLink>; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.<br /><searchLink fieldCode="AU" term="%22McQuilten+HA%22">McQuilten HA</searchLink>; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Rowntree+LC%22">Rowntree LC</searchLink>; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Kedzierski+L%22">Kedzierski L</searchLink>; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Wilks+SH%22">Wilks SH</searchLink>; Department of Electrical and Electronic Engineering, University of Melbourne, Melbourne, Victoria 3010, Australia.; Victorian Infectious Diseases Reference Laboratory, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.<br /><searchLink fieldCode="AU" term="%22McKay+MR%22">McKay MR</searchLink>; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.; Department of Electrical and Electronic Engineering, University of Melbourne, Melbourne, Victoria 3010, Australia.; Victorian Infectious Diseases Reference Laboratory, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Tannock+GA%22">Tannock GA</searchLink>; Burnet Institute, Melbourne, Victoria 3004, Australia.<br /><searchLink fieldCode="AU" term="%22Kent+SJ%22">Kent SJ</searchLink>; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.; Melbourne Sexual Health Centre and Department of Infectious Diseases, Alfred Health, Central Clinical School, Monash University, Melbourne, Victoria 3004, Australia.<br /><searchLink fieldCode="AU" term="%22Laurie+K%22">Laurie K</searchLink>; CSL Seqirus Ltd., Melbourne, Victoria 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Fox+A%22">Fox A</searchLink>; WHO Collaborating Centre for Reference and Research on Influenza, Royal Melbourne Hospital, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.; Department of Infectious Diseases, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Rockman+S%22">Rockman S</searchLink>; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.; CSL Seqirus Ltd., Melbourne, Victoria 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Brown+LE%22">Brown LE</searchLink>; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.; Institute for Vaccine Research and Development, Hokkaido University, Sapporo, Hokkaido 060-0808, Japan.<br /><searchLink fieldCode="AU" term="%22Chung+AW%22">Chung AW</searchLink>; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Wheatley+AK%22">Wheatley AK</searchLink>; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.<br /><searchLink fieldCode="AU" term="%22Kedzierska+K%22">Kedzierska K</searchLink>; Department of Microbiology and Immunology, University of Melbourne, Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.; Institute for Vaccine Research and Development, Hokkaido University, Sapporo, Hokkaido 060-0808, Japan.
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