Clinicopathologic and molecular predictors of survival in BRCA-deficient tubo-ovarian high-grade serous carcinoma.

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Title: Clinicopathologic and molecular predictors of survival in BRCA-deficient tubo-ovarian high-grade serous carcinoma.
Authors: Zwimpfer TA; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia. tibor.zwimpfer@petermac.org.; Department of Biomedicine, University of Basel, Basel, Switzerland. tibor.zwimpfer@petermac.org.; Gynecological Cancer Centre, University Hospital Basel, Basel, Switzerland. tibor.zwimpfer@petermac.org., Fereday S; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; The Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia., Pandey A; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Ariyaratne D; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Jayawardana MW; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; The Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia., Twomey L; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Laumont CM; Deeley Research Centre, BC Cancer, Victoria, BC, Canada., Kennedy CJ; Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, NSW, Australia.; Department of Gynaecological Oncology, Westmead Hospital, Sydney, NSW, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia., Bolithon A; School of Clinical Medicine, UNSW Medicine and Health, University of NSW Sydney, Sydney, NSW, Australia.; Adult Cancer Program, Lowy Cancer Research Centre, University of NSW Sydney, Sydney, New South Wales, 2052, Australia., Meagher NS; School of Clinical Medicine, UNSW Medicine and Health, University of NSW Sydney, Sydney, NSW, Australia.; The Daffodil Centre, The University of Sydney, a joint venture with Cancer Council NSW, Sydney, NSW, Australia., Milne K; Deeley Research Centre, BC Cancer, Victoria, BC, Canada., Hamilton P; Deeley Research Centre, BC Cancer, Victoria, BC, Canada., Alsop J; Department of Oncology, University of Cambridge, Cambridge, UK., Antoniou AC; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK., Au-Yeung G; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; The Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia., Beckmann MW; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg. University Hospital Erlangen, Erlangen, Germany., Berrington de Gonzalez A; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Bisinotto C; Department of Gynecology and Obstetrics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Blome F; Institute of Pathology and Neuropathology, Tuebingen University Hospital, Tuebingen, Germany., Bodelon C; Department of Population Science, American Cancer Society, Atlanta, GA, USA., Boros J; Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, NSW, Australia.; Department of Gynaecological Oncology, Westmead Hospital, Sydney, NSW, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia., Brand AH; Department of Gynaecological Oncology, Westmead Hospital, Sydney, NSW, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia., Carney ME; Department of Obstetrics and Gynecology, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, USA., Cazorla-Jiménez A; Pathology Department, Fundación Jiménez Díaz, Madrid, Spain., Chiu DS; British Columbia's Gynecological Cancer Research Team OVCARE, University of British Columbia, BC Cancer and Vancouver General Hospital, Vancouver, BC, Canada., Christie EL; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; The Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia., Chudecka-Głaz A; Department of Gynecological Surgery and Gynecological Oncology of Adults and Adolescents, Pomeranian Medical University, Szczecin, Poland., Coulson P; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Cushing-Haugen KL; Division of Public Health Sciences, Program in Epidemiology, Fred Hutchinson Cancer Center, Seattle, WA, USA., Cybulski C; Department of Comparative Biomedical Sciences, College of Veterinary Medicine, Mississippi State University, Starkville, MS, USA., Darcy KM; Department of Gynecologic Surgery and Obstetrics, Gynecologic Cancer Center of Excellence, Uniformed Services University of the Health Sciences, Walter Reed National Military Medical Center, Bethesda, MD, USA.; IHenry M Jackson Foundation for the Advancement of Military Medicine, nc, Bethesda, MD, USA., David C; Gynaecological Cancer Centre, Royal Hospital for Women, Randwick, NSW, Australia., Davidson T; NSW Health Pathology, Prince of Wales Hospital, Sydney, NSW, Australia.; School of Medicine, Western Sydney University, Penrith, NSW, Australia., Ekici AB; Institute of Human Genetics. Comprehensive Cancer Center Erlangen-EMN, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg FAU, Erlangen, Germany., Elishaev E; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Emons J; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg. University Hospital Erlangen, Erlangen, Germany., Engler T; Department of Women's Health, Tuebingen University Hospital, Tuebingen, Germany., Farrell R; Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.; Prince of Wales Private Hospital, Randwick, NSW, Australia., Fischer A; Institute of Pathology and Neuropathology, Tuebingen University Hospital, Tuebingen, Germany., García-Closas M; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Gentry-Maharaj A; MRC Clinical Trials Unit, Institute of Clinical Trials and Methodology, University College London, London, UK.; Department of Women's Cancer, Elizabeth Garrett Anderson Institute for Women's Health, University College London, London, UK., Ghatage P; Division of Gynecologic Oncology, Department of Oncology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada., Glasspool R; Beatson West of Scotland Cancer Centre and School of Cancer Sciences, University of Glasgow, Glasgow, UK., Harter P; Department of Gynecology and Gynecologic Oncology, Evangelische Kliniken Essen-Mitte, Essen, Germany., Hartkopf AD; Department of Women's Health, Tuebingen University Hospital, Tuebingen, Germany.; Department of Gynecology and Obstetrics, University Hospital of Ulm, Ulm, Germany., Hartmann A; Institute of Pathology, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany., Heikaus S; Center for Pathology, Evangelische Kliniken Essen-Mitte, Essen, Germany., Hernandez BY; University of Hawaii Cancer Center, Honolulu, HI, USA., Hettiaratchi A; The Health Precincts Biobank, UNSW Biospecimen Services, Mark Wainwright Analytical Centre, UNSW, Sydney, NSW, Australia., Heublein S; Department of Obstetrics and Gynecology, University Hospital Heidelberg, Heidelberg, Germany., Huntsman DG; Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC, Canada.; Department of Molecular Oncology, BC Cancer Research Centre, Vancouver, BC, Canada., Jimenez-Linan M; Department of Histopathology, Addenbrooke's Hospital, Cambridge, UK., Jones ME; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Kang E; Department of Surgery, Seoul National University Bundang Hospital, Seongnam, Republic of Korea., Kaznowska E; Department of Pathology, Institute of Medical Sciences, Medical College of Rzeszow University, Rzeszow, Poland., Kluz T; Department of Gynecology, Gynecology Oncology and Obstetrics, Institute of Medical Sciences, Medical College of Rzeszów University, Rzeszów, Poland., Kommoss FKF; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany., Konecny G; Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA., Kruitwagen RFPM; Department of Obstetrics and Gynecology, Maastricht University Medical Centre, Maastricht, the Netherlands.; GROW Ð School for Oncology and Reproduction, Maastricht University Medical Center, Maastricht, the Netherlands., Kwon J; Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC, Canada., Lambrechts D; Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium.; VIB Center for Cancer Biology, VIB Leuven, Belgium., Lee CH; Department of Pathology and Laboratory Medicine, University of Alberta, Edmonton, AB, Canada., Lester J; Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA., Leung SCY; British Columbia's Gynecological Cancer Research Team OVCARE, University of British Columbia, BC Cancer and Vancouver General Hospital, Vancouver, BC, Canada., Leung Y; Department of Gynaecological Oncology, King Edward Memorial Hospital, Subiaco, WA, Australia.; Division of Obstetrics and Gynaecology, Medical School, University of Western Australia, Crawley, WA, Australia., Linder A; Department of Obstetrics and Gynecology, Institute of Clinical Science, Sahlgrenska Center for Cancer Research, University of Gothenburg, Gothenburg, Sweden., Lissowska J; Department of Cancer Epidemiology and Prevention, M Sklodowska-Curie National Research Oncology Institute, Warsaw, Poland., Loverix L; Division of Gynecologic Oncology, Department of Gynecology and Obstetrics, Leuven Cancer Institute, Leuven, Belgium., Lubiński J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Mateoiu C; Department of Pathology, University of Gothenburg, Gothenburg, Sweden., McNeish IA; Division of Cancer and Ovarian Cancer Action Research Centre, Department Surgery & Cancer, Imperial College London, London, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK., Moubarak M; Department of Gynecology and Gynecologic Oncology, Evangelische Kliniken Essen-Mitte, Essen, Germany., Nelson GS; Division of Gynecologic Oncology, Department of Oncology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada., Nevins N; Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, NSW, Australia.; Department of Gynaecological Oncology, Westmead Hospital, Sydney, NSW, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia., Olawaiye AB; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Olbrecht S; Division of Gynecologic Oncology, Department of Gynecology and Obstetrics, Leuven Cancer Institute, Leuven, Belgium., Orsulic S; Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA., Osorio A; Genetics Service, Fundación Jiménez Díaz University Hospital and Health Research Institute, Universidad Autónoma de Madrid IIS-FJD, UAM, Madrid, Spain.; Centre for Biomedical Network Research on Rare Diseases CIBERER, Instituto de Salud Carlos III, Madrid, Spain., Quinn CM; The Health Precincts Biobank, UNSW Biospecimen Services, Mark Wainwright Analytical Centre, UNSW, Sydney, NSW, Australia., Mohan GR; Department of Gynaecological Oncology, King Edward Memorial Hospital, Subiaco, WA, Australia.; Department of Gynaecological Oncology, St John of God Subiaco Hospital, Subiaco, WA, Australia., Ray-Coquard I; Centre Leon Berard and University Claude Bernard Lyon 1, Lyon, France., Rodríguez-Antona C; Centre for Biomedical Network Research on Rare Diseases CIBERER, Instituto de Salud Carlos III, Madrid, Spain.; Pharmacogenomics and Tumor Biomarkers Group, Institute for Biomedical Research Sols-Morreale CSIC-UAM, Madrid, Spain., Roxburgh P; School of Cancer Sciences, University of Glasgow, Glasgow, UK., Ruebner M; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg. University Hospital Erlangen, Erlangen, Germany., Salfinger SG; Department of Gynaecological Oncology, St John of God Subiaco Hospital, Subiaco, WA, Australia., Samra S; Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, NSW, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.; Tissue Pathology and Diagnostic Oncology, Westmead Hospital, Sydney, NSW, Australia., Schoemaker MJ; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK., Sinn HP; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany., Sonke GS; Department of Medical Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands., Steele L; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA, USA., Stewart CJR; Division of Obstetrics and Gynaecology, Medical School, University of Western Australia, Crawley, WA, Australia., Talhouk A; British Columbia's Gynecological Cancer Research Team OVCARE, University of British Columbia, BC Cancer and Vancouver General Hospital, Vancouver, BC, Canada.; Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC, Canada., Tan A; Division of Obstetrics and Gynaecology, Medical School, University of Western Australia, Crawley, WA, Australia.; Gynaepath WA, Clinipath Sonic Healthcare, Osbourne Park, Australia., Tarney CM; Department of Gynecologic Surgery and Obstetrics, Gynecologic Cancer Center of Excellence, Uniformed Services University of the Health Sciences, Walter Reed National Military Medical Center, Bethesda, MD, USA., Taylor SE; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Van de Vijver KK; Department of Pathology, Ghent University Hospital, Cancer Research Institute Ghent CRIG, Ghent, Belgium.; Department of Pathology, Antwerp University Hospital, Antwerp, Belgium., van der Aa MA; Department of Research, Netherlands Comprehensive Cancer Organization IKNL, Utrecht, the Netherlands., Van Gorp T; Division of Gynaecological Oncology, Leuven Cancer Institute, University Hospital Leuven and KU Leuven, Leuven, Belgium., Van Nieuwenhuysen E; Division of Gynecologic Oncology, Department of Gynecology and Obstetrics, Leuven Cancer Institute, Leuven, Belgium., Van-Wagensveld L; Department of Obstetrics and Gynecology, Maastricht University Medical Centre, Maastricht, the Netherlands.; GROW Ð School for Oncology and Reproduction, Maastricht University Medical Center, Maastricht, the Netherlands.; Department of Research, Netherlands Comprehensive Cancer Organization IKNL, Utrecht, the Netherlands., Wahner-Hendrickson AE; Department of Oncology, Mayo Clinic, Rochester, MN, USA., Walter C; Department of Women's Health, Tuebingen University Hospital, Tuebingen, Germany., Wang C; Department of Quantitative Health Sciences, Division of Computational Biology, Mayo Clinic, Rochester, MN, USA., Welz J; Department of Gynecology and Gynecologic Oncology, Evangelische Kliniken Essen-Mitte, Essen, Germany., Wentzensen N; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Wilkens LR; University of Hawaii Cancer Center, Honolulu, HI, USA., Winham SJ; Department of Quantitative Health Sciences, Division of Computational Biology, Mayo Clinic, Rochester, MN, USA., Winterhoff B; Department of Obstetrics, Gynecology and Women's Health, University of Minnesota, Minneapolis, MN, USA., Anglesio MS; British Columbia's Gynecological Cancer Research Team OVCARE, University of British Columbia, BC Cancer and Vancouver General Hospital, Vancouver, BC, Canada.; Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC, Canada., Berchuck A; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC, USA., Candido Dos Reis FJ; Department of Gynecology and Obstetrics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Cohen PA; Department of Gynaecological Oncology, King Edward Memorial Hospital, Subiaco, WA, Australia.; Division of Obstetrics and Gynaecology, Medical School, University of Western Australia, Crawley, WA, Australia., Conrads TP; Department of Gynecologic Surgery and Obstetrics, Gynecologic Cancer Center of Excellence, Uniformed Services University of the Health Sciences, Walter Reed National Military Medical Center, Bethesda, MD, USA.; Women's Health Integrated Research Center, Women's Service Line, Inova Health System, Falls Church, VA, USA., Crowe P; School of Clinical Medicine, UNSW Medicine and Health, University of NSW Sydney, Sydney, NSW, Australia., Doherty JA; Huntsman Cancer Institute, Department of Population Health Sciences, University of Utah, Salt Lake City, UT, USA., Fasching PA; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg. University Hospital Erlangen, Erlangen, Germany., Fortner RT; Division of Cancer Epidemiology, German Cancer Research Center DKFZ, Heidelberg, Germany.; Department of Research, Cancer Registry of Norway, Norwegian Institute of Public Health, Oslo, Norway., García MJ; Genomic Biomarkers and Precision Oncology Group, Sols-Morreale Biomedical Research Institute IIBM, Consejo Superior de Investigaciones Cientficas & Universidad Autónoma de Madrid CSIC-UAM, Madrid, 28029, Spain., Gayther SA; Medicine, University of Texas Health, San Antonio, TX, USA., Goodman MT; Cancer Prevention and Control Program, Cedars-Sinai Cancer, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Gronwald J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Harris HR; Division of Public Health Sciences, Program in Epidemiology, Fred Hutchinson Cancer Center, Seattle, WA, USA.; Department of Epidemiology, University of Washington School of Public Health, Seattle, WA, USA., Heitz F; Department of Gynecology and Gynecologic Oncology, Evangelische Kliniken Essen-Mitte, Essen, Germany.; Center for Pathology, Evangelische Kliniken Essen-Mitte, Essen, Germany.; Department of Gynecology and Gynecological Oncology, HSK, Dr Horst-Schmidt Klinik, Wiesbaden, Wiesbaden, Germany., Horlings HM; Department of Pathology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek hospital, Amsterdam, the Netherlands., Karlan BY; Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA., Kelemen LE; Communicable Disease Epidemiology Section, South Carolina Department of Public Health, Columbia, SC, USA., Larry Maxwell G; Department of Gynecologic Surgery and Obstetrics, Gynecologic Cancer Center of Excellence, Uniformed Services University of the Health Sciences, Walter Reed National Military Medical Center, Bethesda, MD, USA.; Women's Health Integrated Research Center, Women's Service Line, Inova Health System, Falls Church, VA, USA., Menon U; MRC Clinical Trials Unit, Institute of Clinical Trials and Methodology, University College London, London, UK., Modugno F; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Epidemiology, University of Pittsburgh School of Public Health, Pittsburgh, PA, USA.; Women's Cancer Research Center, Magee-Womens Research Institute and Hillman Cancer Center, Pittsburgh, PA, USA., Neuhausen SL; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA, USA., Schildkraut JM; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA., Staebler A; Institute of Pathology and Neuropathology, Tuebingen University Hospital, Tuebingen, Germany., Sundfeldt K; Department of Obstetrics and Gynecology, Institute of Clinical Science, Sahlgrenska Center for Cancer Research, University of Gothenburg, Gothenburg, Sweden., Swerdlow AJ; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.; Division of Breast Cancer Research, The Institute of Cancer Research, London, UK., Vergote I; Division of Gynecologic Oncology, Department of Gynecology and Obstetrics, Leuven Cancer Institute, Leuven, Belgium., Wu AH; Department of Population Health and Public Health Sciences, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA., Brenton JD; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK., Pharoah PDP; Department of Computational Biomedicine, Cedars-Sinai Medical Center, West Hollywood, CA, USA., Pearce CL; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA., Pike MC; Department of Population Health and Public Health Sciences, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA.; Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA., Goode EL; Division of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA., Ramus SJ; School of Clinical Medicine, UNSW Medicine and Health, University of NSW Sydney, Sydney, NSW, Australia.; Adult Cancer Program, Lowy Cancer Research Centre, University of NSW Sydney, Sydney, New South Wales, 2052, Australia., Köbel M; Department of Pathology and Laboratory Medicine, Foothills Medical Center, University of Calgary, Calgary, AB, Canada., Nelson BH; Deeley Research Centre, BC Cancer, Victoria, BC, Canada.; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, Canada.; Department of Medical Genetics, University of British Columbia, Victoria, BC, Canada., DeFazio A; Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, NSW, Australia.; Department of Gynaecological Oncology, Westmead Hospital, Sydney, NSW, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.; The Daffodil Centre, The University of Sydney, a joint venture with Cancer Council NSW, Sydney, NSW, Australia., Friedlander ML; Gynaecological Cancer Centre, Royal Hospital for Women, Randwick, NSW, Australia.; Nelune Comprehensive Cancer Centre, Prince of Wales Hospital, Sydney, NSW, Australia.; Prince of Wales Clinical School, UNSW Medicine and Health, University of NSW Sydney, Sydney, NSW, Australia., Bowtell DDL; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; The Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia., Garsed DW; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia. Dale.Garsed@petermac.org.; The Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia. Dale.Garsed@petermac.org.
Source: Nature communications [Nat Commun] 2026 Apr 01; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 01.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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Items – Name: Title
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  Data: Clinicopathologic and molecular predictors of survival in BRCA-deficient tubo-ovarian high-grade serous carcinoma.
– Name: Author
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  Data: <searchLink fieldCode="AU" term="%22Zwimpfer+TA%22">Zwimpfer TA</searchLink>; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia. tibor.zwimpfer@petermac.org.; Department of Biomedicine, University of Basel, Basel, Switzerland. tibor.zwimpfer@petermac.org.; Gynecological Cancer Centre, University Hospital Basel, Basel, Switzerland. tibor.zwimpfer@petermac.org.<br /><searchLink fieldCode="AU" term="%22Fereday+S%22">Fereday S</searchLink>; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; The Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Pandey+A%22">Pandey A</searchLink>; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Ariyaratne+D%22">Ariyaratne D</searchLink>; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Jayawardana+MW%22">Jayawardana MW</searchLink>; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; The Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Twomey+L%22">Twomey L</searchLink>; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Laumont+CM%22">Laumont CM</searchLink>; Deeley Research Centre, BC Cancer, Victoria, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Kennedy+CJ%22">Kennedy CJ</searchLink>; Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, NSW, Australia.; Department of Gynaecological Oncology, Westmead Hospital, Sydney, NSW, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Bolithon+A%22">Bolithon A</searchLink>; School of Clinical Medicine, UNSW Medicine and Health, University of NSW Sydney, Sydney, NSW, Australia.; Adult Cancer Program, Lowy Cancer Research Centre, University of NSW Sydney, Sydney, New South Wales, 2052, Australia.<br /><searchLink fieldCode="AU" term="%22Meagher+NS%22">Meagher NS</searchLink>; School of Clinical Medicine, UNSW Medicine and Health, University of NSW Sydney, Sydney, NSW, Australia.; The Daffodil Centre, The University of Sydney, a joint venture with Cancer Council NSW, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Milne+K%22">Milne K</searchLink>; Deeley Research Centre, BC Cancer, Victoria, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Hamilton+P%22">Hamilton P</searchLink>; Deeley Research Centre, BC Cancer, Victoria, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Alsop+J%22">Alsop J</searchLink>; Department of Oncology, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Antoniou+AC%22">Antoniou AC</searchLink>; Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Au-Yeung+G%22">Au-Yeung G</searchLink>; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; The Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Beckmann+MW%22">Beckmann MW</searchLink>; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg. University Hospital Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Berrington+de+Gonzalez+A%22">Berrington de Gonzalez A</searchLink>; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Bisinotto+C%22">Bisinotto C</searchLink>; Department of Gynecology and Obstetrics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.<br /><searchLink fieldCode="AU" term="%22Blome+F%22">Blome F</searchLink>; Institute of Pathology and Neuropathology, Tuebingen University Hospital, Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22Bodelon+C%22">Bodelon C</searchLink>; Department of Population Science, American Cancer Society, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Boros+J%22">Boros J</searchLink>; Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, NSW, Australia.; Department of Gynaecological Oncology, Westmead Hospital, Sydney, NSW, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Brand+AH%22">Brand AH</searchLink>; Department of Gynaecological Oncology, Westmead Hospital, Sydney, NSW, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Carney+ME%22">Carney ME</searchLink>; Department of Obstetrics and Gynecology, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, USA.<br /><searchLink fieldCode="AU" term="%22Cazorla-Jiménez+A%22">Cazorla-Jiménez A</searchLink>; Pathology Department, Fundación Jiménez Díaz, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Chiu+DS%22">Chiu DS</searchLink>; British Columbia's Gynecological Cancer Research Team OVCARE, University of British Columbia, BC Cancer and Vancouver General Hospital, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Christie+EL%22">Christie EL</searchLink>; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; The Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Chudecka-Głaz+A%22">Chudecka-Głaz A</searchLink>; Department of Gynecological Surgery and Gynecological Oncology of Adults and Adolescents, Pomeranian Medical University, Szczecin, Poland.<br /><searchLink fieldCode="AU" term="%22Coulson+P%22">Coulson P</searchLink>; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Cushing-Haugen+KL%22">Cushing-Haugen KL</searchLink>; Division of Public Health Sciences, Program in Epidemiology, Fred Hutchinson Cancer Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Cybulski+C%22">Cybulski C</searchLink>; Department of Comparative Biomedical Sciences, College of Veterinary Medicine, Mississippi State University, Starkville, MS, USA.<br /><searchLink fieldCode="AU" term="%22Darcy+KM%22">Darcy KM</searchLink>; Department of Gynecologic Surgery and Obstetrics, Gynecologic Cancer Center of Excellence, Uniformed Services University of the Health Sciences, Walter Reed National Military Medical Center, Bethesda, MD, USA.; IHenry M Jackson Foundation for the Advancement of Military Medicine, nc, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22David+C%22">David C</searchLink>; Gynaecological Cancer Centre, Royal Hospital for Women, Randwick, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Davidson+T%22">Davidson T</searchLink>; NSW Health Pathology, Prince of Wales Hospital, Sydney, NSW, Australia.; School of Medicine, Western Sydney University, Penrith, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Ekici+AB%22">Ekici AB</searchLink>; Institute of Human Genetics. Comprehensive Cancer Center Erlangen-EMN, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg FAU, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Elishaev+E%22">Elishaev E</searchLink>; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Emons+J%22">Emons J</searchLink>; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg. University Hospital Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Engler+T%22">Engler T</searchLink>; Department of Women's Health, Tuebingen University Hospital, Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22Farrell+R%22">Farrell R</searchLink>; Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.; Prince of Wales Private Hospital, Randwick, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Fischer+A%22">Fischer A</searchLink>; Institute of Pathology and Neuropathology, Tuebingen University Hospital, Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22García-Closas+M%22">García-Closas M</searchLink>; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Gentry-Maharaj+A%22">Gentry-Maharaj A</searchLink>; MRC Clinical Trials Unit, Institute of Clinical Trials and Methodology, University College London, London, UK.; Department of Women's Cancer, Elizabeth Garrett Anderson Institute for Women's Health, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Ghatage+P%22">Ghatage P</searchLink>; Division of Gynecologic Oncology, Department of Oncology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Glasspool+R%22">Glasspool R</searchLink>; Beatson West of Scotland Cancer Centre and School of Cancer Sciences, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Harter+P%22">Harter P</searchLink>; Department of Gynecology and Gynecologic Oncology, Evangelische Kliniken Essen-Mitte, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Hartkopf+AD%22">Hartkopf AD</searchLink>; Department of Women's Health, Tuebingen University Hospital, Tuebingen, Germany.; Department of Gynecology and Obstetrics, University Hospital of Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Hartmann+A%22">Hartmann A</searchLink>; Institute of Pathology, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Heikaus+S%22">Heikaus S</searchLink>; Center for Pathology, Evangelische Kliniken Essen-Mitte, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Hernandez+BY%22">Hernandez BY</searchLink>; University of Hawaii Cancer Center, Honolulu, HI, USA.<br /><searchLink fieldCode="AU" term="%22Hettiaratchi+A%22">Hettiaratchi A</searchLink>; The Health Precincts Biobank, UNSW Biospecimen Services, Mark Wainwright Analytical Centre, UNSW, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Heublein+S%22">Heublein S</searchLink>; Department of Obstetrics and Gynecology, University Hospital Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Huntsman+DG%22">Huntsman DG</searchLink>; Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC, Canada.; Department of Molecular Oncology, BC Cancer Research Centre, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Jimenez-Linan+M%22">Jimenez-Linan M</searchLink>; Department of Histopathology, Addenbrooke's Hospital, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Jones+ME%22">Jones ME</searchLink>; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Kang+E%22">Kang E</searchLink>; Department of Surgery, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kaznowska+E%22">Kaznowska E</searchLink>; Department of Pathology, Institute of Medical Sciences, Medical College of Rzeszow University, Rzeszow, Poland.<br /><searchLink fieldCode="AU" term="%22Kluz+T%22">Kluz T</searchLink>; Department of Gynecology, Gynecology Oncology and Obstetrics, Institute of Medical Sciences, Medical College of Rzeszów University, Rzeszów, Poland.<br /><searchLink fieldCode="AU" term="%22Kommoss+FKF%22">Kommoss FKF</searchLink>; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Konecny+G%22">Konecny G</searchLink>; Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kruitwagen+RFPM%22">Kruitwagen RFPM</searchLink>; Department of Obstetrics and Gynecology, Maastricht University Medical Centre, Maastricht, the Netherlands.; GROW Ð School for Oncology and Reproduction, Maastricht University Medical Center, Maastricht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Kwon+J%22">Kwon J</searchLink>; Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Lambrechts+D%22">Lambrechts D</searchLink>; Laboratory for Translational Genetics, Department of Human Genetics, KU Leuven, Leuven, Belgium.; VIB Center for Cancer Biology, VIB Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Lee+CH%22">Lee CH</searchLink>; Department of Pathology and Laboratory Medicine, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Lester+J%22">Lester J</searchLink>; Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Leung+SCY%22">Leung SCY</searchLink>; British Columbia's Gynecological Cancer Research Team OVCARE, University of British Columbia, BC Cancer and Vancouver General Hospital, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Leung+Y%22">Leung Y</searchLink>; Department of Gynaecological Oncology, King Edward Memorial Hospital, Subiaco, WA, Australia.; Division of Obstetrics and Gynaecology, Medical School, University of Western Australia, Crawley, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Linder+A%22">Linder A</searchLink>; Department of Obstetrics and Gynecology, Institute of Clinical Science, Sahlgrenska Center for Cancer Research, University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Lissowska+J%22">Lissowska J</searchLink>; Department of Cancer Epidemiology and Prevention, M Sklodowska-Curie National Research Oncology Institute, Warsaw, Poland.<br /><searchLink fieldCode="AU" term="%22Loverix+L%22">Loverix L</searchLink>; Division of Gynecologic Oncology, Department of Gynecology and Obstetrics, Leuven Cancer Institute, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Lubiński+J%22">Lubiński J</searchLink>; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.<br /><searchLink fieldCode="AU" term="%22Mateoiu+C%22">Mateoiu C</searchLink>; Department of Pathology, University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22McNeish+IA%22">McNeish IA</searchLink>; Division of Cancer and Ovarian Cancer Action Research Centre, Department Surgery & Cancer, Imperial College London, London, UK.; School of Cancer Sciences, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Moubarak+M%22">Moubarak M</searchLink>; Department of Gynecology and Gynecologic Oncology, Evangelische Kliniken Essen-Mitte, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Nelson+GS%22">Nelson GS</searchLink>; Division of Gynecologic Oncology, Department of Oncology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Nevins+N%22">Nevins N</searchLink>; Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, NSW, Australia.; Department of Gynaecological Oncology, Westmead Hospital, Sydney, NSW, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Olawaiye+AB%22">Olawaiye AB</searchLink>; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Olbrecht+S%22">Olbrecht S</searchLink>; Division of Gynecologic Oncology, Department of Gynecology and Obstetrics, Leuven Cancer Institute, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Orsulic+S%22">Orsulic S</searchLink>; Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Osorio+A%22">Osorio A</searchLink>; Genetics Service, Fundación Jiménez Díaz University Hospital and Health Research Institute, Universidad Autónoma de Madrid IIS-FJD, UAM, Madrid, Spain.; Centre for Biomedical Network Research on Rare Diseases CIBERER, Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Quinn+CM%22">Quinn CM</searchLink>; The Health Precincts Biobank, UNSW Biospecimen Services, Mark Wainwright Analytical Centre, UNSW, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Mohan+GR%22">Mohan GR</searchLink>; Department of Gynaecological Oncology, King Edward Memorial Hospital, Subiaco, WA, Australia.; Department of Gynaecological Oncology, St John of God Subiaco Hospital, Subiaco, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Ray-Coquard+I%22">Ray-Coquard I</searchLink>; Centre Leon Berard and University Claude Bernard Lyon 1, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Rodríguez-Antona+C%22">Rodríguez-Antona C</searchLink>; Centre for Biomedical Network Research on Rare Diseases CIBERER, Instituto de Salud Carlos III, Madrid, Spain.; Pharmacogenomics and Tumor Biomarkers Group, Institute for Biomedical Research Sols-Morreale CSIC-UAM, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Roxburgh+P%22">Roxburgh P</searchLink>; School of Cancer Sciences, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Ruebner+M%22">Ruebner M</searchLink>; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg. University Hospital Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Salfinger+SG%22">Salfinger SG</searchLink>; Department of Gynaecological Oncology, St John of God Subiaco Hospital, Subiaco, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Samra+S%22">Samra S</searchLink>; Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, NSW, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.; Tissue Pathology and Diagnostic Oncology, Westmead Hospital, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Schoemaker+MJ%22">Schoemaker MJ</searchLink>; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Sinn+HP%22">Sinn HP</searchLink>; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Sonke+GS%22">Sonke GS</searchLink>; Department of Medical Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Steele+L%22">Steele L</searchLink>; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA, USA.<br /><searchLink fieldCode="AU" term="%22Stewart+CJR%22">Stewart CJR</searchLink>; Division of Obstetrics and Gynaecology, Medical School, University of Western Australia, Crawley, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Talhouk+A%22">Talhouk A</searchLink>; British Columbia's Gynecological Cancer Research Team OVCARE, University of British Columbia, BC Cancer and Vancouver General Hospital, Vancouver, BC, Canada.; Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Tan+A%22">Tan A</searchLink>; Division of Obstetrics and Gynaecology, Medical School, University of Western Australia, Crawley, WA, Australia.; Gynaepath WA, Clinipath Sonic Healthcare, Osbourne Park, Australia.<br /><searchLink fieldCode="AU" term="%22Tarney+CM%22">Tarney CM</searchLink>; Department of Gynecologic Surgery and Obstetrics, Gynecologic Cancer Center of Excellence, Uniformed Services University of the Health Sciences, Walter Reed National Military Medical Center, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Taylor+SE%22">Taylor SE</searchLink>; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Van+de+Vijver+KK%22">Van de Vijver KK</searchLink>; Department of Pathology, Ghent University Hospital, Cancer Research Institute Ghent CRIG, Ghent, Belgium.; Department of Pathology, Antwerp University Hospital, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22van+der+Aa+MA%22">van der Aa MA</searchLink>; Department of Research, Netherlands Comprehensive Cancer Organization IKNL, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Van+Gorp+T%22">Van Gorp T</searchLink>; Division of Gynaecological Oncology, Leuven Cancer Institute, University Hospital Leuven and KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Van+Nieuwenhuysen+E%22">Van Nieuwenhuysen E</searchLink>; Division of Gynecologic Oncology, Department of Gynecology and Obstetrics, Leuven Cancer Institute, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Van-Wagensveld+L%22">Van-Wagensveld L</searchLink>; Department of Obstetrics and Gynecology, Maastricht University Medical Centre, Maastricht, the Netherlands.; GROW Ð School for Oncology and Reproduction, Maastricht University Medical Center, Maastricht, the Netherlands.; Department of Research, Netherlands Comprehensive Cancer Organization IKNL, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Wahner-Hendrickson+AE%22">Wahner-Hendrickson AE</searchLink>; Department of Oncology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Walter+C%22">Walter C</searchLink>; Department of Women's Health, Tuebingen University Hospital, Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22Wang+C%22">Wang C</searchLink>; Department of Quantitative Health Sciences, Division of Computational Biology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Welz+J%22">Welz J</searchLink>; Department of Gynecology and Gynecologic Oncology, Evangelische Kliniken Essen-Mitte, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Wentzensen+N%22">Wentzensen N</searchLink>; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Wilkens+LR%22">Wilkens LR</searchLink>; University of Hawaii Cancer Center, Honolulu, HI, USA.<br /><searchLink fieldCode="AU" term="%22Winham+SJ%22">Winham SJ</searchLink>; Department of Quantitative Health Sciences, Division of Computational Biology, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Winterhoff+B%22">Winterhoff B</searchLink>; Department of Obstetrics, Gynecology and Women's Health, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Anglesio+MS%22">Anglesio MS</searchLink>; British Columbia's Gynecological Cancer Research Team OVCARE, University of British Columbia, BC Cancer and Vancouver General Hospital, Vancouver, BC, Canada.; Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Berchuck+A%22">Berchuck A</searchLink>; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Candido+Dos+Reis+FJ%22">Candido Dos Reis FJ</searchLink>; Department of Gynecology and Obstetrics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.<br /><searchLink fieldCode="AU" term="%22Cohen+PA%22">Cohen PA</searchLink>; Department of Gynaecological Oncology, King Edward Memorial Hospital, Subiaco, WA, Australia.; Division of Obstetrics and Gynaecology, Medical School, University of Western Australia, Crawley, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Conrads+TP%22">Conrads TP</searchLink>; Department of Gynecologic Surgery and Obstetrics, Gynecologic Cancer Center of Excellence, Uniformed Services University of the Health Sciences, Walter Reed National Military Medical Center, Bethesda, MD, USA.; Women's Health Integrated Research Center, Women's Service Line, Inova Health System, Falls Church, VA, USA.<br /><searchLink fieldCode="AU" term="%22Crowe+P%22">Crowe P</searchLink>; School of Clinical Medicine, UNSW Medicine and Health, University of NSW Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Doherty+JA%22">Doherty JA</searchLink>; Huntsman Cancer Institute, Department of Population Health Sciences, University of Utah, Salt Lake City, UT, USA.<br /><searchLink fieldCode="AU" term="%22Fasching+PA%22">Fasching PA</searchLink>; Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg. University Hospital Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Fortner+RT%22">Fortner RT</searchLink>; Division of Cancer Epidemiology, German Cancer Research Center DKFZ, Heidelberg, Germany.; Department of Research, Cancer Registry of Norway, Norwegian Institute of Public Health, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22García+MJ%22">García MJ</searchLink>; Genomic Biomarkers and Precision Oncology Group, Sols-Morreale Biomedical Research Institute IIBM, Consejo Superior de Investigaciones Cientficas & Universidad Autónoma de Madrid CSIC-UAM, Madrid, 28029, Spain.<br /><searchLink fieldCode="AU" term="%22Gayther+SA%22">Gayther SA</searchLink>; Medicine, University of Texas Health, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Goodman+MT%22">Goodman MT</searchLink>; Cancer Prevention and Control Program, Cedars-Sinai Cancer, Cedars-Sinai Medical Center, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gronwald+J%22">Gronwald J</searchLink>; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.<br /><searchLink fieldCode="AU" term="%22Harris+HR%22">Harris HR</searchLink>; Division of Public Health Sciences, Program in Epidemiology, Fred Hutchinson Cancer Center, Seattle, WA, USA.; Department of Epidemiology, University of Washington School of Public Health, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Heitz+F%22">Heitz F</searchLink>; Department of Gynecology and Gynecologic Oncology, Evangelische Kliniken Essen-Mitte, Essen, Germany.; Center for Pathology, Evangelische Kliniken Essen-Mitte, Essen, Germany.; Department of Gynecology and Gynecological Oncology, HSK, Dr Horst-Schmidt Klinik, Wiesbaden, Wiesbaden, Germany.<br /><searchLink fieldCode="AU" term="%22Horlings+HM%22">Horlings HM</searchLink>; Department of Pathology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek hospital, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Karlan+BY%22">Karlan BY</searchLink>; Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kelemen+LE%22">Kelemen LE</searchLink>; Communicable Disease Epidemiology Section, South Carolina Department of Public Health, Columbia, SC, USA.<br /><searchLink fieldCode="AU" term="%22Larry+Maxwell+G%22">Larry Maxwell G</searchLink>; Department of Gynecologic Surgery and Obstetrics, Gynecologic Cancer Center of Excellence, Uniformed Services University of the Health Sciences, Walter Reed National Military Medical Center, Bethesda, MD, USA.; Women's Health Integrated Research Center, Women's Service Line, Inova Health System, Falls Church, VA, USA.<br /><searchLink fieldCode="AU" term="%22Menon+U%22">Menon U</searchLink>; MRC Clinical Trials Unit, Institute of Clinical Trials and Methodology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Modugno+F%22">Modugno F</searchLink>; Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Epidemiology, University of Pittsburgh School of Public Health, Pittsburgh, PA, USA.; Women's Cancer Research Center, Magee-Womens Research Institute and Hillman Cancer Center, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Neuhausen+SL%22">Neuhausen SL</searchLink>; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, CA, USA.<br /><searchLink fieldCode="AU" term="%22Schildkraut+JM%22">Schildkraut JM</searchLink>; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Staebler+A%22">Staebler A</searchLink>; Institute of Pathology and Neuropathology, Tuebingen University Hospital, Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22Sundfeldt+K%22">Sundfeldt K</searchLink>; Department of Obstetrics and Gynecology, Institute of Clinical Science, Sahlgrenska Center for Cancer Research, University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Swerdlow+AJ%22">Swerdlow AJ</searchLink>; Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK.; Division of Breast Cancer Research, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Vergote+I%22">Vergote I</searchLink>; Division of Gynecologic Oncology, Department of Gynecology and Obstetrics, Leuven Cancer Institute, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Wu+AH%22">Wu AH</searchLink>; Department of Population Health and Public Health Sciences, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Brenton+JD%22">Brenton JD</searchLink>; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Pharoah+PDP%22">Pharoah PDP</searchLink>; Department of Computational Biomedicine, Cedars-Sinai Medical Center, West Hollywood, CA, USA.<br /><searchLink fieldCode="AU" term="%22Pearce+CL%22">Pearce CL</searchLink>; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Pike+MC%22">Pike MC</searchLink>; Department of Population Health and Public Health Sciences, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA.; Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Goode+EL%22">Goode EL</searchLink>; Division of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Ramus+SJ%22">Ramus SJ</searchLink>; School of Clinical Medicine, UNSW Medicine and Health, University of NSW Sydney, Sydney, NSW, Australia.; Adult Cancer Program, Lowy Cancer Research Centre, University of NSW Sydney, Sydney, New South Wales, 2052, Australia.<br /><searchLink fieldCode="AU" term="%22Köbel+M%22">Köbel M</searchLink>; Department of Pathology and Laboratory Medicine, Foothills Medical Center, University of Calgary, Calgary, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Nelson+BH%22">Nelson BH</searchLink>; Deeley Research Centre, BC Cancer, Victoria, BC, Canada.; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, Canada.; Department of Medical Genetics, University of British Columbia, Victoria, BC, Canada.<br /><searchLink fieldCode="AU" term="%22DeFazio+A%22">DeFazio A</searchLink>; Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, NSW, Australia.; Department of Gynaecological Oncology, Westmead Hospital, Sydney, NSW, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.; The Daffodil Centre, The University of Sydney, a joint venture with Cancer Council NSW, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Friedlander+ML%22">Friedlander ML</searchLink>; Gynaecological Cancer Centre, Royal Hospital for Women, Randwick, NSW, Australia.; Nelune Comprehensive Cancer Centre, Prince of Wales Hospital, Sydney, NSW, Australia.; Prince of Wales Clinical School, UNSW Medicine and Health, University of NSW Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Bowtell+DDL%22">Bowtell DDL</searchLink>; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; The Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Garsed+DW%22">Garsed DW</searchLink>; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia. Dale.Garsed@petermac.org.; The Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia. Dale.Garsed@petermac.org.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2026 Apr 01; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Apr 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41467-026-71134-3
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      – TitleFull: Clinicopathologic and molecular predictors of survival in BRCA-deficient tubo-ovarian high-grade serous carcinoma.
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      – PersonEntity:
          Name:
            NameFull: DeFazio A
      – PersonEntity:
          Name:
            NameFull: Friedlander ML
      – PersonEntity:
          Name:
            NameFull: Bowtell DDL
      – PersonEntity:
          Name:
            NameFull: Garsed DW
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 04
              Text: 2026 Apr 01
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 2041-1723
          Numbering:
            – Type: volume
              Value: 17
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Nature communications
              Type: main
ResultId 1