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Generation of a novel Dysferlin microdeletion knock-in mouse model mimicking muscular dystrophy-like pathology.

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Title: Generation of a novel Dysferlin microdeletion knock-in mouse model mimicking muscular dystrophy-like pathology.
Authors: Chen YL; Center for Precision Medicine and Genomics, Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.; Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan., Lin WN; Graduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University, New Taipei City, Taiwan.; Center for Health Research and Innovation, Fu Jen Catholic University, New Taipei City, Taiwan., Pan PY; Graduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University, New Taipei City, Taiwan., Ku WC; School of Medicine, College of Medicine, Fu Je Catholic University, New Taipei City, Taiwan., Wang P; School of Medicine, College of Medicine, Fu Je Catholic University, New Taipei City, Taiwan., Yip PK; School of Medicine, College of Medicine, Fu Je Catholic University, New Taipei City, Taiwan.; Division of Neurology, Cardinal Tien Hospital, New Taipei City, Taiwan., Tsui KC; School of Medicine, College of Medicine, Fu Je Catholic University, New Taipei City, Taiwan.; Department of Medical Research, Cathay General Hospital, Taipei, Taiwan.; Division of Infectious Diseases, Department of Internal Medicine, Cathay General Hospital, Taipei, Taiwan., Wu YN; Center for Health Research and Innovation, Fu Jen Catholic University, New Taipei City, Taiwan. 133838@mail.fju.edu.tw.; School of Medicine, College of Medicine, Fu Je Catholic University, New Taipei City, Taiwan. 133838@mail.fju.edu.tw., Lin YH; Graduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University, New Taipei City, Taiwan. 084952@mail.fju.edu.tw.; Center for Health Research and Innovation, Fu Jen Catholic University, New Taipei City, Taiwan. 084952@mail.fju.edu.tw.
Source: Scientific reports [Sci Rep] 2026 Apr 01; Vol. 16 (1). Date of Electronic Publication: 2026 Apr 01.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Generation of a novel Dysferlin microdeletion knock-in mouse model mimicking muscular dystrophy-like pathology.
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  Data: <searchLink fieldCode="AU" term="%22Chen+YL%22">Chen YL</searchLink>; Center for Precision Medicine and Genomics, Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.; Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+WN%22">Lin WN</searchLink>; Graduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University, New Taipei City, Taiwan.; Center for Health Research and Innovation, Fu Jen Catholic University, New Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Pan+PY%22">Pan PY</searchLink>; Graduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University, New Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ku+WC%22">Ku WC</searchLink>; School of Medicine, College of Medicine, Fu Je Catholic University, New Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+P%22">Wang P</searchLink>; School of Medicine, College of Medicine, Fu Je Catholic University, New Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yip+PK%22">Yip PK</searchLink>; School of Medicine, College of Medicine, Fu Je Catholic University, New Taipei City, Taiwan.; Division of Neurology, Cardinal Tien Hospital, New Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsui+KC%22">Tsui KC</searchLink>; School of Medicine, College of Medicine, Fu Je Catholic University, New Taipei City, Taiwan.; Department of Medical Research, Cathay General Hospital, Taipei, Taiwan.; Division of Infectious Diseases, Department of Internal Medicine, Cathay General Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+YN%22">Wu YN</searchLink>; Center for Health Research and Innovation, Fu Jen Catholic University, New Taipei City, Taiwan. 133838@mail.fju.edu.tw.; School of Medicine, College of Medicine, Fu Je Catholic University, New Taipei City, Taiwan. 133838@mail.fju.edu.tw.<br /><searchLink fieldCode="AU" term="%22Lin+YH%22">Lin YH</searchLink>; Graduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University, New Taipei City, Taiwan. 084952@mail.fju.edu.tw.; Center for Health Research and Innovation, Fu Jen Catholic University, New Taipei City, Taiwan. 084952@mail.fju.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2026 Apr 01; Vol. 16 (1). <i>Date of Electronic Publication: </i>2026 Apr 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101563288 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2045-2322 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220452322%22">20452322 </searchLink><i>NLM ISO Abbreviation: </i>Sci Rep <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41598-026-46635-2
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        Text: English
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              Text: 2026 Apr 01
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