Spatially-guided metabolomics profiling of metabolic regions in human tumor tissues.

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Title: Spatially-guided metabolomics profiling of metabolic regions in human tumor tissues.
Authors: Lee JJ; Bioinformatics Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Zhang J; Singapore Phenome Center, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Chew SC; Programme in Translational and Clinical Liver Research, National Cancer Centre Singapore, Singapore, Singapore., Loong S; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore., Xu L; Singapore Phenome Center, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Kong JC; Bioinformatics Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Grigoryev F; Bioinformatics Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Chung AY; Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Surgery Academic Clinical Programme, Duke-NUS Medical School Singapore, Singapore, Singapore., Teo JY; Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Surgery Academic Clinical Programme, Duke-NUS Medical School Singapore, Singapore, Singapore., Cheow PC; Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Surgery Academic Clinical Programme, Duke-NUS Medical School Singapore, Singapore, Singapore., Bonney G; Division of Hepatobiliary & Pancreatic Surgery, Department of Surgery, University Surgical Cluster, National University Health System, Singapore, Singapore., Goh BKP; Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Surgery Academic Clinical Programme, Duke-NUS Medical School Singapore, Singapore, Singapore., Leow WQ; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore., Wang Y; Singapore Phenome Center, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore. yulan.wang@ntu.edu.sg.; Human Phenome Institute, Fudan University, Shanghai, China. yulan.wang@ntu.edu.sg., Loo LH; Bioinformatics Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. loolh@a-star.edu.sg., Chow PK; Programme in Translational and Clinical Liver Research, National Cancer Centre Singapore, Singapore, Singapore. pierce.chow@duke-nus.edu.sg.; Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore. pierce.chow@duke-nus.edu.sg.; Surgery Academic Clinical Programme, Duke-NUS Medical School Singapore, Singapore, Singapore. pierce.chow@duke-nus.edu.sg.
Source: Molecular systems biology [Mol Syst Biol] 2026 Jul; Vol. 22 (7), pp. 1132-1160. Date of Electronic Publication: 2026 Apr 01.
Publication Type: Journal Article
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101235389 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-4292 (Electronic) Linking ISSN: 17444292 NLM ISO Abbreviation: Mol Syst Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Spatially-guided metabolomics profiling of metabolic regions in human tumor tissues.
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  Data: <searchLink fieldCode="AU" term="%22Lee+JJ%22">Lee JJ</searchLink>; Bioinformatics Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Singapore Phenome Center, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Chew+SC%22">Chew SC</searchLink>; Programme in Translational and Clinical Liver Research, National Cancer Centre Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Loong+S%22">Loong S</searchLink>; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Xu+L%22">Xu L</searchLink>; Singapore Phenome Center, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Kong+JC%22">Kong JC</searchLink>; Bioinformatics Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Grigoryev+F%22">Grigoryev F</searchLink>; Bioinformatics Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Chung+AY%22">Chung AY</searchLink>; Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Surgery Academic Clinical Programme, Duke-NUS Medical School Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Teo+JY%22">Teo JY</searchLink>; Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Surgery Academic Clinical Programme, Duke-NUS Medical School Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Cheow+PC%22">Cheow PC</searchLink>; Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Surgery Academic Clinical Programme, Duke-NUS Medical School Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Bonney+G%22">Bonney G</searchLink>; Division of Hepatobiliary & Pancreatic Surgery, Department of Surgery, University Surgical Cluster, National University Health System, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Goh+BKP%22">Goh BKP</searchLink>; Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.; Surgery Academic Clinical Programme, Duke-NUS Medical School Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Leow+WQ%22">Leow WQ</searchLink>; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Singapore Phenome Center, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore. yulan.wang@ntu.edu.sg.; Human Phenome Institute, Fudan University, Shanghai, China. yulan.wang@ntu.edu.sg.<br /><searchLink fieldCode="AU" term="%22Loo+LH%22">Loo LH</searchLink>; Bioinformatics Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. loolh@a-star.edu.sg.<br /><searchLink fieldCode="AU" term="%22Chow+PK%22">Chow PK</searchLink>; Programme in Translational and Clinical Liver Research, National Cancer Centre Singapore, Singapore, Singapore. pierce.chow@duke-nus.edu.sg.; Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore. pierce.chow@duke-nus.edu.sg.; Surgery Academic Clinical Programme, Duke-NUS Medical School Singapore, Singapore, Singapore. pierce.chow@duke-nus.edu.sg.
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  Data: <searchLink fieldCode="JN" term="%22101235389%22">Molecular systems biology</searchLink> [Mol Syst Biol] 2026 Jul; Vol. 22 (7), pp. 1132-1160. <i>Date of Electronic Publication: </i>2026 Apr 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22EMBO+Press%22">EMBO Press </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101235389 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1744-4292 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217444292%22">17444292 </searchLink><i>NLM ISO Abbreviation: </i>Mol Syst Biol <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s44320-026-00205-w
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      – Code: eng
        Text: English
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        StartPage: 1132
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      – TitleFull: Spatially-guided metabolomics profiling of metabolic regions in human tumor tissues.
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            – D: 01
              M: 07
              Text: 2026 Jul
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