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Personalized fMRI-Guided TMS Targeting the Threat Neurocircuitry in PTSD: A Randomized Clinical Trial.

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Title: Personalized fMRI-Guided TMS Targeting the Threat Neurocircuitry in PTSD: A Randomized Clinical Trial.
Authors: van Rooij SJH; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta., Langhinrichsen-Rohling R; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta., Minton ST; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta., Hinojosa CA; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta.; Department of Psychology, University of New Mexico, Albuquerque., Lukemire J; Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta., Lipschutz R; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta., Hinrichs R; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta., Merrill N; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta., Ely TD; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta., Dahlgren K; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta., Sompolpong P; Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta., Job G; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta., Riva-Posse P; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta., Holtzheimer PE; National Center for PTSD, White River Junction, VT.; Departments of Psychiatry and Surgery, Geisel School of Medicine, Dartmouth College, Hanover, NH., Calhoun VD; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta.; Tri-institutional Center for Translational Research in Neuroimaging and Data Science, Georgia State, Georgia Tech, Emory, Atlanta., Camprodon JA; Department of Psychiatry, Harvard Medical School, Boston.; Division of Neuropsychiatry and Interventional Psychiatry, Mass General Brigham, Boston., Rauch SAM; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta.; Joseph Maxwell Cleland Atlanta VA Healthcare System, Atlanta., Kaslow NJ; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta., Ressler KJ; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta.; Department of Psychiatry, Harvard Medical School, Boston.; Division of Depression and Anxiety Disorders, McLean Hospital, Belmont, MA., Jovanovic T; Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit., McDonald WM; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta.
Source: The American journal of psychiatry [Am J Psychiatry] 2026 May 01; Vol. 183 (5), pp. 343-354. Date of Electronic Publication: 2026 Apr 02.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: American Psychiatric Association Country of Publication: United States NLM ID: 0370512 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-7228 (Electronic) Linking ISSN: 0002953X NLM ISO Abbreviation: Am J Psychiatry Subsets: MEDLINE
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  Data: Personalized fMRI-Guided TMS Targeting the Threat Neurocircuitry in PTSD: A Randomized Clinical Trial.
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  Data: <searchLink fieldCode="AU" term="%22van+Rooij+SJH%22">van Rooij SJH</searchLink>; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta.<br /><searchLink fieldCode="AU" term="%22Langhinrichsen-Rohling+R%22">Langhinrichsen-Rohling R</searchLink>; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta.<br /><searchLink fieldCode="AU" term="%22Minton+ST%22">Minton ST</searchLink>; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta.<br /><searchLink fieldCode="AU" term="%22Hinojosa+CA%22">Hinojosa CA</searchLink>; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta.; Department of Psychology, University of New Mexico, Albuquerque.<br /><searchLink fieldCode="AU" term="%22Lukemire+J%22">Lukemire J</searchLink>; Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta.<br /><searchLink fieldCode="AU" term="%22Lipschutz+R%22">Lipschutz R</searchLink>; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta.<br /><searchLink fieldCode="AU" term="%22Hinrichs+R%22">Hinrichs R</searchLink>; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta.<br /><searchLink fieldCode="AU" term="%22Merrill+N%22">Merrill N</searchLink>; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta.<br /><searchLink fieldCode="AU" term="%22Ely+TD%22">Ely TD</searchLink>; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta.<br /><searchLink fieldCode="AU" term="%22Dahlgren+K%22">Dahlgren K</searchLink>; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta.<br /><searchLink fieldCode="AU" term="%22Sompolpong+P%22">Sompolpong P</searchLink>; Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta.<br /><searchLink fieldCode="AU" term="%22Job+G%22">Job G</searchLink>; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta.<br /><searchLink fieldCode="AU" term="%22Riva-Posse+P%22">Riva-Posse P</searchLink>; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta.<br /><searchLink fieldCode="AU" term="%22Holtzheimer+PE%22">Holtzheimer PE</searchLink>; National Center for PTSD, White River Junction, VT.; Departments of Psychiatry and Surgery, Geisel School of Medicine, Dartmouth College, Hanover, NH.<br /><searchLink fieldCode="AU" term="%22Calhoun+VD%22">Calhoun VD</searchLink>; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta.; Tri-institutional Center for Translational Research in Neuroimaging and Data Science, Georgia State, Georgia Tech, Emory, Atlanta.<br /><searchLink fieldCode="AU" term="%22Camprodon+JA%22">Camprodon JA</searchLink>; Department of Psychiatry, Harvard Medical School, Boston.; Division of Neuropsychiatry and Interventional Psychiatry, Mass General Brigham, Boston.<br /><searchLink fieldCode="AU" term="%22Rauch+SAM%22">Rauch SAM</searchLink>; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta.; Joseph Maxwell Cleland Atlanta VA Healthcare System, Atlanta.<br /><searchLink fieldCode="AU" term="%22Kaslow+NJ%22">Kaslow NJ</searchLink>; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta.<br /><searchLink fieldCode="AU" term="%22Ressler+KJ%22">Ressler KJ</searchLink>; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta.; Department of Psychiatry, Harvard Medical School, Boston.; Division of Depression and Anxiety Disorders, McLean Hospital, Belmont, MA.<br /><searchLink fieldCode="AU" term="%22Jovanovic+T%22">Jovanovic T</searchLink>; Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit.<br /><searchLink fieldCode="AU" term="%22McDonald+WM%22">McDonald WM</searchLink>; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta.
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  Data: <searchLink fieldCode="JN" term="%220370512%22">The American journal of psychiatry</searchLink> [Am J Psychiatry] 2026 May 01; Vol. 183 (5), pp. 343-354. <i>Date of Electronic Publication: </i>2026 Apr 02.
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